Citation:Dewasurendra, D.M.W., Peiris, K.P.P., Karunarathna, E.D.C. and Sudesh, A.D.H. (2017). Microbiological study of an indigenous mouth wash (Gandusha) used in periodontal diseases. Salakya Sandipani, Department of Shalya Shalakya,Gampaha Wickramarachchi Ayurveda Institute,University of Kelaniya,Sri Lanka.p 128.
Date:2017
Abstract:
Mouth wash (Gandusha) is clinically effective in the management of periodontal diseases. This
study is an in-vitro analysis on determining the antimicrobial efcacy of this drug using standard
Antimicrobial Sensitivity Test against a fungal culture isolated from a patient. The test was
performed according to the Well diffusion method having 6mm diameter wells on Sabouraud
Dextrose Agar (SDA). Each well was loaded with the test drug mixed in 20μl of sterile distilled
water and uconazole 2.5mg / ml was used as the positive control. According to the results, the
test drug showed an average Inhibition Zone Diameter (IZD) of 19mm while the positive control
showed IZD of 15mm. Therefore, it can be stated that the test drug is more effective than the
positive control and the isolated culture is sensitive to the test drug as it had shown an IZD of
19mm while it is intermediate sensitive for the positive control as 15mm comes under
Intermediate sensitive range (15-18mm). These results support the claim that the indigenous
mouth wash (Gandusha) is effective in the management of periodontal diseases.
