YARIS - 2019

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Effects of therapeutic purgation procedure on renal function and serum electrolytes level
(Young Ayurveda Researchers' and Innovators' Symposium (YARIS – 2019), Institutional Research Committee, Gampaha Wickramarachchi Ayurveda Institute, University of Kelaniya, Yakkala, Sri Lanka, 2019) Alagiyawanna, A.M.A.N.N.; Dissanayake, K.G.C.
Therapeutic purgation is one among the Panchakarma therapies, which eliminates excessive vitiated Dosha mostly the Pitta Dosha from the body through the anal route. Under normal circumstances, if a patient suffers from diarrhea, there is certainly the loss of electrolytes from the body resulting in weakness, development of cramps due to dehydration and sometimes low blood pressure and renal failure. However, if purgation is induced through Virechana therapy and if features of proper Virechana occur, no such symptoms will occur. After purgation, if there is an electrolyte imbalance or deformity in renal function, it needs to be evaluated and the levels are to be compared before and after Virechana therapy. The present study was designed to determine the effect of therapeutic purgation procedure on renal function and serum electrolytes level. All the patients were selected from the IPD of Gampaha Wickramarachchi Ayurveda Hospital, Yakkala. Simple random sampling method was used to select the patients. 16 patients were selected according to the selection criteria. Before starting the treatment procedure Renal function test report and Serum electrolytes level report were taken from testing a blood sample of each patient. Deepana pachana drugs were given for 03 days and then the internal oleation started. Internal oleation continued for 05 days. Sudation was given in the evening of last day of internal oleation and morning and evening of the following day. Pitta uthkleshaka diet was given as the dinner. The following morning purgative drugs were given. After 02 days of proper purgation therapy required tests were done. A follow up was done after one month. Research group resulted significant change in blood urea, serum creatinine levels and serum electrolytes levels. Thus, the purgation therapy has a significant effect on renal function and serum electrolytes levels
Effects of therapeutic purgation procedure on liver function and electrical activity of heart
(Young Ayurveda Researchers' and Innovators' Symposium (YARIS – 2019), Institutional Research Committee, Gampaha Wickramarachchi Ayurveda Institute, University of Kelaniya, Yakkala, Sri Lanka, 2019) Gamage, H.P.
Communicable diseases are a main health problem in the present world. Diseases of heart and liver are most common among them. Therefore, this study was conducted to determine the effect of therapeutic purgation on liver function and the electrical activity of the heart. Therapeutic purgation eliminates excessive vitiated dosha, mostly the Pitta dosha from the body through the anal route. After purgation, if there is a deformity in liver function or electrical activity of heart, it needs to be evaluated and the levels are to be compared before and after purgation therapy. In the present study, all the patients were selected from the IPD of Gampaha Wickramarachchi Ayurveda Hospital, Yakkala. Simple random sampling method was used to select the patients. 16 patients were selected according to the selection criteria. Before starting the treatment procedure liver function test report and electrocardiogram were taken from each patient. Deepana-Pachana drugs were given for 03 days and then the internal oleation started. Internal oleation continued for 05 days. Sedation was given in the evening of the last day of internal oleation and on the following day morning purgative drugs were given. After 02 days of proper purgation therapy, required tests were done. A follow up was done after one month of proper purgation. The patients showed significant reduction in liver function tests (SGOT, SGPT and Serum bilirubin). But in this study, significant changes of electrical activity of the heart were not presented. Thus, the therapeutic purgation could be recommended for the management of liver diseases, specially for fatty liver when purgation is appropriate
Evaluation of effects of herbal formula mentioned in “Aushada Samgraha” in the management of Suryavartha
(Young Ayurveda Researchers' and Innovators' Symposium (YARIS – 2019), Institutional Research Committee, Gampaha Wickramarachchi Ayurveda Institute, University of Kelaniya, Yakkala, Sri Lanka, 2019) De Silva, W.C.S.
Suryavartha is the commonest clinical condition which is directly related with the position of the sun in the sky. The symptomatology of Suryavartha reveals its close resemblance with that of frontal sinusitis. This study aimed at finding the efficacy of a herbal formula oil including Dashamoola, thila thaila and Cow’s milk. Assessment of the effect of treatment was done on the basis of relief of those subjective and objective parameters of Suryavartha under a grading system. Twenty four patients had engaged in this study and eight patients were instructed to use herbal formula oil and another eight patients were given internal medicine and the others were given both research oil and internal medicine. Observations were recorded after one month. According to SPSS data analyzed P value in the comparison between before and after treatment of Group A, B and C, for all parameters P values were less than 0.05 of Group A and B. But in group C, P value is less than 0.05 only for headache and nasal discharge before and after treatments. According to the clinical study in all groups there is an improvement of reducing the symptoms after 4 weeks of treatment period. But there is a marked improvement of reducing symptoms in the group which was given both research oil and internal medicine. The improvement of reducing symptoms in the group which was given research oil is better than the group which was given only internal medicine. It can be concluded that herbal formula is more effective with the internal medicine in the management of Suryavartha.
Evaluation of the clinical efficacy of Śāriwothphalādi lepa in the management of migraine
(Young Ayurveda Researchers' and Innovators' Symposium (YARIS – 2019), Institutional Research Committee, Gampaha Wickramarachchi Ayurveda Institute, University of Kelaniya, Yakkala, Sri Lanka, 2019) Vithana, V.K.V.N.; Kasthurirathna, K.T.S.C.
Headaches are classified as primary and secondary. Migraine is the most common of primary headache disorders. Migraine disorders are further classified into migraine without aura, migraine with aura, familial or sporadic hemiplegic migraine, and basilar-type migraine. Complications of migraines include chronic migraine, status migrainous, persistent aura without infarction, migrainous infarction, and migraine-triggered seizures. Migraine has different symptoms; it may be different from person to person. This study aimed at finding the efficacy of an herbal formula lepa including Hemidesmus indicus, Nymphaea lotus L., Saussurea lappa, Glycyrrhiza glabra L. which was a safe and effective external mode of therapy for migraine without side effects. Throbbing, pulsating pain, photophobia, phonophobia, nausea & vomiting, visual disturbance, tinnitus and duration of headache were assessment criteria & assessment of the effect of treatment was done on the basis of relief of the subjective and objective parameters of migraine under a grading system. Thirty patients had engaged in this study. All were advised to avoid the other treatments for migraine & apply the lepa on pained area, when they feel migraine. Observations were recorded after six months. While considering the P value of symptoms, P value <0.05 for throbbing, pulsating pain, photophobia, phonophobia, visual disturbance, duration of headache. So Śariwothphaladi lepa is effective on these five symptoms. But P value>0.05 for nausea and vomiting, tinnitus. So it is not effective on these two symptoms. According to pharmacodynamics action, it has Pitta shamaka and Kapha wardaka property. So it has deep sleepy condition after using Śariwothphaladi lepa. It is helpful to reduce symptoms of migraine quickly. According to the study Śariwothphaladi lepa has given effect for reducing the symptoms of migraine. Finally, it was confirmed that Śariwothphaladi lepa is effective in the management of migraine.
Evaluation of the efficacy of leech application in the management of immature cataract
(Young Ayurveda Researchers' and Innovators' Symposium (YARIS – 2019), Institutional Research Committee, Gampaha Wickramarachchi Ayurveda Institute, University of Kelaniya, Yakkala, Sri Lanka, 2019) Uyanege, P.P.
Visual disorders have been represented the most complex problem in the field of ophthalmology and has been of great interest since the dawn of human life on this earth. While immature cataract is a physiological anomaly of accommodation, which is very common and almost occurs to all persons around 40 years of age, it cannot accommodate the near object distinctly due to loss of plasticity of the lens due to aging process. Our ancient text known as Susruthasamhitha has given much attention to these types of eye disorders. While describing the Drishtigatha Rogas he elaborately described the Patalas and its pathological disorders leading to immature cataract. This is for the 1st time, the treatment modality in the management of immature cataract is taken for research work. In the clinical study 28 eyes of patients were selected and divided in to two groups. Leech application was done to group A and Anjana therapy was done to group B. Subjective and objective criteria were used as parameters to assess the improvement. From the observations and results which were received from this study , it can be concluded that Group A, was provided better results in the symptoms of sameepastha/ durastha Avyaktha darshana ,Vihwaladarshana, Dwidhadarshana, headache and eye strain .The treatment given to group B, has been positive for symptoms of Sameepastha / durastha Avyakhtha darshana, dwidhadarshana and headache. Leech therapy is effective for symptoms of Vihwaladarshana and eye strain than Anjana therapy. Treatments given for all 2 groups were successful for visual acuity (distant vision, near vision), Lenticular Opacity and red reflex. In nutshell, both treatments are in significant level when considering p - value. When comparing p - value of the treatments p value of the Anjana therapy is more significant than the Leech therapy
Evaluation of the herbal formula mentioned in Rajaushadhanidhiya in the management of Pityriasis Versicolor
(Young Ayurveda Researchers' and Innovators' Symposium (YARIS – 2019), Institutional Research Committee, Gampaha Wickramarachchi Ayurveda Institute, University of Kelaniya, Yakkala, Sri Lanka, 2019) Nilmini, R.R.P.S.; Dissanayake, K.G.C.
Pityriasis versicolor is a common skin condition that produces well demarcated round or oval macules on the trunk, neck, and upper arms where the density of sebaceous glands is high. These lesions often appear as hyper-pigmented patches on lighter skin types and hypo-pigmented patches on darker or tanned skin and can vary in color. There are many treatments in Ayurveda, to relieve Pityriasis versicolor. The formula used for the present study is an external application, mentioned in Rajaushadhanidhiya; however, the effects are not scientifically proven. The present study aimed at finding the efficacy of this herbal formula composed of Ipomoea obscura, Curcuma longa, Cassia fistula, Phylenthes emblica. Thirty patients were recruited for this study and fifteen patients were advised to apply herbal formula and for others Nimbhadilepa for one month without other treatments for Pityriasis versicolor. The size, colour, clinical form, itching of affected areas were graded by the researchers before and after the treatment. Data were analyzed using Statistical Package for the Social Sciences (SPSS) and Microsoft Excel. A significant reduction (p value <0.05) in size, itching, colour and clinical form of affected areas was observed after the treatment in Test group. Although P value<0.05 in size and itching of affected areas, P value>0.05 in colour and clinical form in control group. It can be concluded that the tested herbal formula has a better effect than Nimbhadilepa on reducing the symptoms of Pityriasis versicolor.
The effect of selected Yoga postures in the management of obesity and overweight with special reference to Body Mass Index
(Young Ayurveda Researchers' and Innovators' Symposium (YARIS – 2019), Institutional Research Committee, Gampaha Wickramarachchi Ayurveda Institute, University of Kelaniya, Yakkala, Sri Lanka, 2019) Ekanayake, E.M.C.K.; Dissanayake, K.G.C.
In world, more than half of adults and just below 20% children are overweight or obese. Yoga can improve strength and flexibility and may help control physiological variables such as blood pressure, lipids, respiration, heart rate and metabolic rate to improve overall exercise capacity. It is hypothesized that overweight and obesity can be managed by practicing selected Yoga. This study was focused on evaluation of the effects of yogic practice on overweight and obesity. Thirty overweight and obese patients were selected according to the inclusion and exclusion criteria from Gampaha Wickramarachchi Ayurveda Teaching Hospital. Body Mass Index, Waist hip ratio, Pulse rate, Skin fold thickness, Blood Pressure were estimated before the study. Overweight and obesity were assessed by using Body Mass Index (BMI). The patients were treated with seven types of Yoga asana, pranayama and meditation and prescribed dietary management during the period of 1 month. After the study, calculated p value for Body Mass Index is 0.00, which is less than 0.01. H0 was rejected at 1% significant level. Calculated p value for Waist hip ration is 0.00 which is less than 0.01. H0 was rejected at 1% significant level. Calculated p value for Pulse rate is 0.001, which is less than 0.01. H0 was rejected at 1% significant level. Calculated p value for Skin fold thickness is 0.00, which is less than 0.01. H0 was rejected at 1% significant level. Calculated p value for Systolic blood pressure is 0.01, which is equal to 0.01. H0 was rejected at 1% significant level. Calculated p value for Diastolic blood pressure is 0.01, which is equal to 0.01. H0 was rejected at 1% significant level. Therefore, there is a significant difference between above mentioned parameters before and after doing Yoga. Thus, the selected Yoga postures could be recommended in the management of overweight and obesity
Evaluation of the effects of herbal formula mentioned in “Rajaushadhanidhiya” in the management of cracked feet
(Young Ayurveda Researchers' and Innovators' Symposium (YARIS – 2019), Institutional Research Committee, Gampaha Wickramarachchi Ayurveda Institute, University of Kelaniya, Yakkala, Sri Lanka, 2019) Ekneligoda, R.V.
Cracked feet are characterized by yellowing of skin on the heel, hard skin growth, cracked and peeling skin and sometimes causing deep fissures that can be painful or bleed. Cracked feet can be correlated with “Padadari”. This study aimed at finding the efficacy of herbal formula mentioned in “Rajaushadhnidhiya” for cracked feet. So far no known scientific study has been conducted to evaluate the effect of herbal oil which is made by using Cocos nucifera and Euphorbia antiquorum in treatment of cracked feet. In clinical study thirty patients were selected and randomly divided into two groups. The research group was treated by applying herbal oil over the cracked area of heel after washing with hot water in the morning and evening for 14 consecutive days. The control group was given no any application. The responses to the treatments were evaluated by using a specially prepared grading scale for the clinical features. The results showed significant reduction in number of cracks, depth of cracks, roughness, dryness, pain and itching of the feet in the research group. The research group showed p = 0.001 for number of cracks in the feet, p = 0.004 for the depth of cracks in feet, p = 0.000 for the roughness of the feet, p = 0.000 for the dryness of the feet, p = 0.001 for the pain in the feet and p = 0.334 for the itching of the feet. None of the patients experienced the aggravation of symptoms or any hypersensitivity reactions. So it can be concluded that the herbal oil is effective in managing cracked feet.
A post-treatment assessment on the quality of life of Prameha (Diabetic) patients; a study conducted at Prameha clinic in Bandaranaike Memorial Ayurveda Research Institute
(Young Ayurveda Researchers' and Innovators' Symposium (YARIS – 2019), Institutional Research Committee, Gampaha Wickramarachchi Ayurveda Institute, University of Kelaniya, Yakkala, Sri Lanka, 2019) Wasana, P.D.L.; Dilupa, M.K.N.; Madusanka, B.P.R.; Wijekumara, A.B.A.T.; Herath, H.M.N.P.; Asna, M.S.F.; Weerapana, W.; Mendis, R.; Kahingala, P.; Hewagamage, P.; Attanayake, S.
According to Ayurveda, Prameha refers to the passing of urine, qualified by prefix “Pra”, the excess in both frequency and quantity .The name Prameha is self-explanatory, which means “Prabhuthamutrata” (excessive urination) and “Avilamutratha” (Turbid urine). There are twenty types of Prameha. All types of urinary abnormalities are developed to Madhumeha, unless treated in early diagnosis and it becomes incurable. Diabetes mellitus resembles with Prameha in signs and symptoms. Diabetes is multifactorial disease which emerges as an irreversible outcome of a combination of metabolic and modifiable risk factors and is one of the leading non communicable diseases (NCDs) that affects morbidity, mortality and disability in the world. Diabetes is divided into 2 major subgroups as, Type I Diabetes mellitus (Insulin Deficiency) and Type II Diabetes mellitus (Insulin Resistant). It is mainly driven by unhealthy diets, insufficient physical activities, obesity and overweight. Quality of life is the general well-being of individuals and societies, outlining negative and positive features of life. It observes life satisfaction, including everything from physical health, family, education, employment, wealth, safety, security, freedom, religious beliefs, finance and the environment. This study was designed to identify the quality of life of Prameha patients who received Ayurveda treatment at Prameha Clinic in Bandaranaike Memorial Ayurveda Research Institute, Navinna, Sri Lanka. Cross- descriptive research (prospective study) was carried out at Prameha Clinic in this institute and accessed by 50 Prameha (diabetic) patients with SF 36 stranded questionnaire distributed among those who received treatment only under Ayurveda drug modalities. According to data analysis of the variables of general health, limitations of activities, physical health, emotional health problems, social activities, pain and energy and emotions the null hypothesis was rejected and the alternative hypothesis was accepted at the significant level p<0.05. It can be concluded that there was an improvement of quality of life of the subjected patients.
Antibacterial activity of Maha Thuwāla Thaila against laboratory specimens of Staphylococcus aureus: an experimental study
(Young Ayurveda Researchers' and Innovators' Symposium (YARIS – 2019), Institutional Research Committee, Gampaha Wickramarachchi Ayurveda Institute, University of Kelaniya, Yakkala, Sri Lanka, 2019) Thiwanthika, U.A.C.; Vitharana, P.
Ayurveda and indigenous herbal preparations are used in the treatment of various types of infectious wounds. They are composed of many herbs which naturally contain anti-microbial compounds. They can be effectively used against bacterial and fungal infections. Maha Thuwāla Thaila is a medicine for external application which is mostly used in indigenous medicine in Sri Lanka to cure chronic wounds, cut-injury wounds, orthopedic wounds and burned wounds. In addition, this oil preparation is clinically used in orthopedic treatment (Sandi Baghna Cikitsa) to cure Sandi Baghna. It consists of many herbs, oils, spices and minerals which have a number of anti-bacterial and anti-fungal compounds. Generally, all types of skin wounds are colonized by various types of bacteria. Common among these bacteria types is Staphylococcus aureus which is considered the classic opportunist bacteria which takes advantage of broken skin or other entry sites to cause an infection. But efficacy of this oil against Staphylococcus aureus in wounds is not scientifically evaluated. The purpose of this study was to evaluate tthe ant-bacterial activity of Maha Thuwāla Thaila against the laboratory specimen of Staphylococcus aureus by using Anti-bacterial Susceptibility Test (ABST). In this study Amoxicillin (5 mg/ml) was used as a positive control. The tested oil sample has shown 8.83 mm mean inhibitory zone diameter while positive control showed 39.33 mm of mean diameter. This result concludes that the tested samples of Maha Thuwāla Thaila showed less significant anti-bacterial activity against the laboratory specimens of Staphylococcus aureus bacteria under these laboratory conditions
Management of Acne vulgaris (Mukha dushika) with Ayurveda treatment modality: A case study
(Young Ayurveda Researchers' and Innovators' Symposium (YARIS – 2019), Institutional Research Committee, Gampaha Wickramarachchi Ayurveda Institute, University of Kelaniya, Yakkala, Sri Lanka, 2019) Wasana, P.D.L.; Dharmavijaya, P.K.H.
Acne is a common skin disease especially in adolescents and young adults. Significant psychosocial effects such as depression and poor personality development have been linked with acne. Various causative factors as well as physical and psychological factors have been contributed towards acne. Various treatment methods of acne including surgery, laser treatments, antibiotics and topical applications and cosmetics products with chemicals are associated with many side effects. In Ayurveda, acne resembles as Mukha dusika and also has broad management procedure including external and internal treatment with congenial diet and lifestyle (Pathyapathya). A 27 years old female patient presented in OPD at Gampaha Wickramarachchi Ayurveda Teaching Hospital, Yakkala with the complaint of pimples on bilateral face associated with pain for 3years. The patient was prescribed poly herbal formulated decoction including Shreshta Nimba, Gayathri Thriphala, Ushiran Chandanan, Shatawari Gopakanya for each in 14 days and Khaishor Guggulu, Thriphala vati in required dose for each in 30 days respectively as internal administration. As an external application, purification of face with juice of Nimba leaves and wet turmeric and application of the paste of Dashangalepa powder mixed with king coconut water, rose water were done respectively each in 14 days. In addition, Pathyapathya was prescribed. After two months of treatment period, pimples were reduced from severe to mild stage. It was observed 100% relief of reduction of pain. According to above data, it was found that there was a significant difference between before and after treatments. Based on the above finding, it can be concluded that the treatment protocol is effective for Acne Vulgaris (Mukha dushika).
Preparation and standardization of Thirasthawalu Churna
(Young Ayurveda Researchers' and Innovators' Symposium (YARIS – 2019), Institutional Research Committee, Gampaha Wickramarachchi Ayurveda Institute, University of Kelaniya, Yakkala, Sri Lanka, 2019) Fernando, K.A.B.; Wijayabandara, J.; Welivitigoda, C.; Jeewanthi, J.A.H.; Kumara, J.M.U.M.; Kumara, M.D.K.A.; Nilanika, C.; Ahila, A.
The world is witnessing an unprecedented growth in the usage of herbal products. Sri Lanka is also a mother hub for natural herbs based science. Herbal drug technology is used for converting botanical into medicines, and for standardization and quality control with proper integration of modern scientific techniques and traditional knowledge. WHO Specific guidelines are used for the assessment of the safety, efficacy, quality and purity throughout all phases of its cycle for global harmonization. An overview was done covering the different techniques involved in standardization of crude or finished compound drugs so far as macroscopic, microscopic, physical, chemical and biological methods. Standardization of the individual ingredients help to be responsible for the desired pharmacological effect. The study initiated with the preparation and standardization of the Thirasthawalu Churna. Thirasthawalu Churna was mentioned in Ola leaves manuscript No - 564. The herbal preparation consists of Perumkayam, Vadakaha, Rathnetul, Viyali Inguru, Asamodagam, Aralu, Suwadakottan and Thirasthavalu as ingredients and recommended in the treatment of Kusapilika (Abdominal cancer). The organoleptic characters such as color, taste, odor, smell and consistency for Aralu and Thirasthawalu were evaluated. Physicochemical parameters were determined as per WHO guidelines and reported as total ash, acid insoluble ash, moisture, pH, water soluble extractive, ethanol soluble extractive and Thin Layer Chromatography (TLC) developed for different solvent systems. Detection of TLC finger print profiles were carried under UV light at the wavelength of 254nm and 366nm and also color of the spots were recorded after derivate with Ethanol sulphuric acid regent. The procedures developed in the present study will serve as a protocol for the herbal preparation which minimizes batch to batch variation with assure safety, efficacy, quality and acceptability as an herbal that is used in Kusa pilika and Grahani. Further studies are needed to ensure standardization of other ingredients
Evaluation of the deodorant action of Nagakesara
(Young Ayurveda Researchers' and Innovators' Symposium (YARIS – 2019), Institutional Research Committee, Gampaha Wickramarachchi Ayurveda Institute, University of Kelaniya, Yakkala, Sri Lanka, 2019) Hazari, F.S.; Jayasinghe, J.M.P.R.K.
Sweating is a natural process that our body goes through each and every day. The purpose of sweating is to cool the body down and remove toxins. But heavy sweating causes problems or distress. It is caused by spicy foods, hard works, caffeine, mental issues and hereditary. Because of the above etiological factors, the body temperature rises and the sympathetic nerve stimulates the sweat glands to produce excessive secretion which leads to clinical manifestations like disruption of normal activities, wet palms, hands, arm pits, frequent sweating, noticeable sweating that soaks that we clothing, skin problems, stained cloths and body odor. A clinical study was designed to evaluate the deodorant action of Nagakeshara (mesuaferrea). The study was carried out on 60 patients of both sexes between 16 - 40 years with complaints of frequent sweating, noticeable sweating that soaks to the cloths, odor formation and color change in axillary region. Two groups were selected and the test group was used to test the deodorant action of the Nagakeshara and ghee (Lepa A). Control group was used to test the action of the ghee (Lepa B). The study was carried out for 21 days. According to the results in present study, it could be concluded that short term administration of the drug has shown significant effect decreasing the severity of the disease.
Evaluation of the antibacterial effect of Acronychia pedunculata fresh extract against Staphylococcus aureus: a study in vitro
(Young Ayurveda Researchers' and Innovators' Symposium (YARIS – 2019), Institutional Research Committee, Gampaha Wickramarachchi Ayurveda Institute, University of Kelaniya, Yakkala, Sri Lanka, 2019) Muthukuda, M.A.C.L
In vitro antibacterial activity of fresh extracts of stem bark, leaves and combined sample of Acronychia pedunculata found in Sri Lanka were investigated against Staphylococcus aureus (ATCC 25923) and found the Minimum Inhibitory Concentration. Kirby Baurer Well diffusion method of antibacterial Susceptibility Testing was used to determine antibacterial activity of each fresh extract. Dilution series for Minimum Inhibitory Concentration were prepared. Amoxacillin and distilled water were used as positive and negative control respectively. Zone diameters were interpreted and data were statistically analyzed. The results showed that there was antibacterial effect of each sample. The highest zone diameter was observed for the combined sample; fresh extracts of stem bark and leaves (11.67mm). This could be due to the synergetic activity of each compound from each plant material used in this study. Fresh extracts of stem bark showed the second most (11mm) and fresh extracts of leaves the least (9mm). As fresh extracts of stem bark and leaves of Acronychia pedunculata (combined sample) showed the highest activity, dilution series from that sample were prepared. The minimum inhibitory concentration of combined sample for the growth of Staphylococcus aureus was 10-2 mg/ml. This could be further investigated for more gram positive and negative bacterial and fungal species. It is worth to investigate each extract individually using various chromatographic techniques and identify the active ingredients separately.
Comparative study of the effect and efficacy of Sesame oil and Ghee on the blood lipid level
(Young Ayurveda Researchers' and Innovators' Symposium (YARIS – 2019), Institutional Research Committee, Gampaha Wickramarachchi Ayurveda Institute, University of Kelaniya, Yakkala, Sri Lanka, 2019) Amarasinghe, K.A.I.; Dissanayake, K.G.C.
In Ayurveda treatments there is a purification method name as purgation mainly aimed at reducing Pitta Dosha in which Dosha is expelled out through the anal passage. Before the purgation therapy Snehapana is done. Generally sesame oil and ghee oil are used in Snehapana. When applying oil internally, blood lipid level can be changed. Various researches have been already carried out on blood lipid level, yet there is a lacuna in the management of blood lipid level. Therefore, this study was undertaken to examine and compare sesame oil and ghee oil on the blood lipid level in the body after the purgation therapy. Hence in the present clinical study, 16 patients were selected and divided into 2 groups. The sesame oil was given to group A and ghee oil was given to group B. All the patients were investigated for total cholesterol level, HDL, Triglyceride, LDL, VLDL and total cholesterol / HDL ratio before and after treatment. According to data, when sesame oil was applied, patient’s total cholesterol, HDL, LDL mean value decreased but ghee oil applied patient’s mean values increased after the treatment. But triglyceride mean value increased after the treatment of both oils. But there was not a significant treatment effect. When considering the overall results of this study, according to the mean value sesame oil can be applied to increased blood lipid level patients but ghee cannot be used
Review on Sri Lankan traditional medical system on fracture healing
(Young Ayurveda Researchers' and Innovators' Symposium (YARIS – 2019), Institutional Research Committee, Gampaha Wickramarachchi Ayurveda Institute, University of Kelaniya, Yakkala, Sri Lanka, 2019) Fernando, K.A.B; Morawaka, A.P.
Sri Lanka has its own indigenous scheme of traditional medicine which is called “Hela Wedakama”. This system has been practiced for many centuries and most of treatments used by native practitioners that have been verbally transmitted or sometimes written in Ola-leaf manuscripts. Traditional treatments for fractures were called by different names such as “Handi Wedakama” or “Kedum Bindum Wedakama” which have a speedy curability with good reputation. Morawaka traditional medical system was very popular for traditional orthopedic medicine with effective treatment modalities. Hence, an attempt was made to review on Morawaka traditional medical system in Sri Lanka for bone fracture healing. Various types of paththu like Inguru paththuwa, Kurundu paththuwa, Vasavasi pththuwa, Ketakela paththuwa, Tiktabin paththuwa and Kalukudu paththuwa have been commonly used for effective healing of fractures. Specific mallum, thavili and oils were used as other external applications for fracture healing in addition to internal medicines of decoctions with specific pathyapathya. Ayurveda properties were analyzed in the raw materials used for fracture healing in this traditional medical system. Vrana shodana, vrana ropana, wedanasthapana, shothahara, bagna sandana, sthambana and raktha wardaka effects were more prominent modes of action in the raw materials with main pharmacodynamic action of vata-kapa pacifying that promotes the fracture healing process. The treatment modalities for bone fractures used by this traditional medical system were very effective with high quality. Further studies are needed to be undertaken to strengthen the knowledge based on traditional medicines with its effective promotion in the health care system
Evaluation of the effect and efficacy of herbal powder preparation derived from ‘Thalpathe Piliyam’ in the management of type II Diabetes mellitus
(Young Ayurveda Researchers' and Innovators' Symposium (YARIS – 2019), Institutional Research Committee, Gampaha Wickramarachchi Ayurveda Institute, University of Kelaniya, Yakkala, Sri Lanka, 2019) Harshamali, K.A.D.T.; Sakunthala, H.S.
Diabetes Mellitus is a metabolic disorder of multiple etiology characterized by chronic hyperglycemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action or both. The effects of Diabetes Mellitus include long-term damage, dysfunction and failure of various organs (WHO, 1999). It is a chronic disease caused by inherited and acquired deficiency in production of insulin by the pancreas or by the ineffectiveness of the insulin produced. Such a deficiency results in increased concentrations of glucose in the blood, which in turn damage many of the body’s systems, especially the blood vessels and nerves. (WHO, 2013) This study was designed to determine the effect and efficacy of selected herbal formulation mentioned in “Thalpathe Piliyam” in the management of type II Diabetes. All patients were selected from medical clinic of Gampaha Wickramarachchi Ayurveda Teaching Hospital according to the inclusion and exclusion criteria. The selected patients were assigned into two groups (group A and B) consisting of 30 patients for each group. The patients of group A were treated with the powder of selected herbal formula and dietary management during the period of 1 month. Patients of group B were treated with allopathic medicine and dietary management during the period of 1 month. After 1 month, the patients of group A and group B showed significant reduction in fasting blood sugar and blood pressure and heart rate. Thus, the powder of selected formulation could be recommended in the management of type II Diabetes
Determination of metal content in Rasna Sapthaka Kwatha
(Young Ayurveda Researchers' and Innovators' Symposium (YARIS – 2019), Institutional Research Committee, Gampaha Wickramarachchi Ayurveda Institute, University of Kelaniya, Yakkala, Sri Lanka, 2019) Abeysingha, W.A.M.U.S.; Nilmini, R.R.P.S.; Rajapakse, C.S.K.; Weerasooriya, W.M.B.
Rasna sapthaka kwatha is a widely used Ayurvedic decoction. Medicinal plants that are the ingredients of this decoction are collected from different habitats of the country. The decoction can be contaminated with metals during the growing, collecting, and storing of the raw material and also during the processing of this product. Hence, the evaluation of metal concentration in pharmaceutically available decoction is of utmost significance. Therefore, the main objective of this research was to determine the concentration of Al, Cr, Cd, Cu, and Pb in decoction samples of Rasna sapthaka kwatha collected from different areas of Sri Lanka. Ten samples of decoction were randomly collected from Anuradhapura, Kurunegala, Kandy, Polonnaruwa, Thambuththegama, Galadiulwewa and Gampaha. Atomic Absorption Spectrometry was used to detect the metal concentration. Wet digestion was carried out prior to the analysis. The mean concentration value of Al, Cd, Cr and Cu were 1.010ppm, 0.232 ppm, 0.387 ppm and 0.155 ppm respectively. Pb was below the detected level of the instrument. Al, Cd, Cr and Cu contents in decoction samples were found in the range of 0.39-2.208 ppm, 0.18-0.348 ppm, 0.33-0.462 ppm, and 0.042-0.408 ppm respectively. Results revealed that the mean values of metal concentration of tested samples were below the recorded WHO permissible level of metals in herbal medicine.
Efficacy of a prepared traditional lepa for the management of Amavata sandi shotha
(Young Ayurveda Researchers' and Innovators' Symposium (YARIS – 2019), Institutional Research Committee, Gampaha Wickramarachchi Ayurveda Institute, University of Kelaniya, Yakkala, Sri Lanka, 2019) Prabash, K.G.D.; Wickramarachchi, W.J.
Amavata is a disease caused by vitiation of Vata by Ama, which is the product of incomplete digestion and metabolism. Agni in Ayurveda includes the digestive processes of gastrointestinal tract as well as the metabolic processes in tissues. Ama could therefore be produced by flawed digestion in gastrointestinal tract or in the tissues by defective metabolic process. Ama thus produced is said to circulate and block the vessel of the joints and get deposited there causing inflammation by producing symptoms such as pain, moving discomfort, swelling and morning stiffness in small and big joints, making a person lame. Various drug trails were already carried out on Amavata, yet there is a lacuna in the management of Ama vata. Therefore this study was undertaken to examine the efficacy of a prepared traditional lepa in the management of Amavata sandi shotha. Hence, in the present clinical study, 30 patients were selected and divided into 2 groups, Group A and B. Group A was given Sarshapa oil and group B the test group was given, traditional lepa. The collected data was recorded according to the age, sex and a paired sample t – test was applied for the clinical assessment of the subjective parameters. During treatment no side effects were noted. According to the analysis all P- values of the test group in the comparison of before and after treatment in full duration were less than 0.05 (P - values before and after treatment on pain (0.000), moving discomfort (0. 000), edema (0. 000), redness (0.012), burning sensation (0.000), ESR (0.010) and Rheumatoid Factor 0.025). The results obtained were significant statistically in traditional lepa. Therefore, the study confirms that the traditional lepa is effective in the management of Amavata sandishotha
Efficacy of Ayurvedic formula mentioned in Susrutasamhitha in the management of Kalithya
(Young Ayurveda Researchers' and Innovators' Symposium (YARIS – 2019), Institutional Research Committee, Gampaha Wickramarachchi Ayurveda Institute, University of Kelaniya, Yakkala, Sri Lanka, 2019) Dharshika, A.K.D.; Wickramarachchi, W.J.
Hair loss becomes one of the common problems in society. Falling hair is one of the diseases of head region, known as “Kalithya” in Ayurveda. There are varieties of reasons for hair loss, including autoimmune diseases, stress, poor nutrition, some medications, mineral deficiency, pollution, severe illness, excessive styling, pregnancy, hereditary and even poor hair care, while wearing helmets and caps can also increase the risk of hair loss. Today more and more people are turning toward the Ayurveda to find a solution for hair loss. Ayurveda believes that hair fall control is very much associated with the body type and also the stability of both body and mind structure of the person. To overcome Kalithya there are many treatments modalities described in Ayurveda texts, like Shirolepa, Shiroabyanga, Shirodhara, Shirovasthi etc. In this study, shirolepa was considered as the treatment modality. Application of medicated paste on the scalp is known as Shirolepa. Most of the shiro lepa are not scientifically evaluated. This formula is one of them mentioned in Susrutasamhitha. Equal quantities of Karanda (Pongamia pinnata) leaves, juice of Kapitta (Limonia acidissima L.) and Kasisa purified using Bhrungaraja (Eclipta alba) decoction were used to make the herbal paste. In the clinical study 20 patients were selected in age between 20-50 years, irrespective of their religion, occupation and habits. They were randomly divided in to two groups. Group A was treated with shiro lepa and group B was treated with Brungamalaka Thaila (traditional effective Thaila for scalp). All of them completed the treatments accurately and the follow up study continued up to one month after treatments. After considering the results, it can be concluded that herbal paste is more effective in fallen hair, itching condition, hair dandruff and hair color except regrowth of the hair