dc.contributor.author |
Smyth, P.P. |
en_US |
dc.contributor.author |
Wijeyaratne, C.N. |
en_US |
dc.contributor.author |
Kaluarachi, W.N. |
en_US |
dc.contributor.author |
Smith, D.F. |
en_US |
dc.contributor.author |
Premawardena, L.D.K.E. |
en_US |
dc.contributor.author |
Parkes, A.B. |
en_US |
dc.contributor.author |
Jayasinghe, A. |
en_US |
dc.contributor.author |
de Silva, D.G.H. |
en_US |
dc.contributor.author |
Lazarus, J.H. |
en_US |
dc.date.accessioned |
2014-10-29T09:23:10Z |
|
dc.date.available |
2014-10-29T09:23:10Z |
|
dc.date.issued |
2005 |
en_US |
dc.identifier.citation |
Thyroid. 2005; 15(5): pp.474-7 |
en_US |
dc.identifier.issn |
1050-7256 (Print) |
en_US |
dc.identifier.issn |
1557-9077 (Electronic) |
en_US |
dc.identifier.uri |
http://repository.kln.ac.lk/handle/123456789/1683 |
|
dc.description |
Indexed in MEDLINE |
|
dc.description.abstract |
Thyroid antibodies were measured sequentially in 25 pregnant women from a Sri Lankan population. A high prevalence of antithyroidantibodies, particularly antithyroglobulin antibodies (TgAb) had previously been demonstrated in female schoolchildren drawn from this population. In the present study TgAb were detected in 36.8% of nonpregnant controls while thyroid peroxidase antibody (TPOAb) positivity was present in 26.3%. The prevalence of both antibodies in the pregnancy study group showed a progressive decline compared to nonpregnant controls throughout gestation becoming undetectable in the third trimester. The results are consistent with an immunosuppressive effect of pregnancy in a population in whom high thyroid autoantibody titers may have resulted from a recent salt iodization program. |
en_US |
dc.publisher |
Mary Ann Liebert Publishers |
en_US |
dc.title |
Sequential studies on thyroid antibodies during pregnancy |
en_US |
dc.type |
Article |
en_US |
dc.identifier.department |
Paediatrics |
en_US |
dc.creator.corporateauthor |
American Thyroid Association |
en_US |
dc.description.note |
Indexed in MEDLINE |
en_US |