Medicine

 

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  • Kilpeläinen, T. O.; Bentley, A. R.; Noordam, R.; Sung, Y. J.; Schwander, K.; Winkler, T. W.; Jakupović, H.; Chasman, D. I.; Manning, A.; Ntalla, I.; Aschard, H.; Brown, M. R.; de Las Fuentes, L.; Franceschini, N.; Guo, X.; Vojinovic, D.; Aslibekyan, S.; Feitosa, M. F.; Kho, M.; Musani, S. K.; Richard, M.; Wang, H.; Wang, Z.; Bartz, T. M.; Bielak, L. F.; Campbell, A.; Dorajoo, R.; Fisher, V.; Hartwig, F. P.; Horimoto, A. R. V. R.; Li, C.; Lohman, K. K.; Marten, J.; Sim, X.; Smith, A. V.; Tajuddin, S. M.; Alver, M.; Amini, M.; Boissel, M.; Chai, J. F.; Chen, X.; Divers, J.; Evangelou, E.; Gao, C.; Graff, M.; Harris, S. E.; He, M.; Hsu, F. C.; Jackson, A. U.; Zhao, J. H.; Kraja, A. T.; Kühnel, B.; Laguzzi, F.; Lyytikäinen, L. P.; Nolte, I. M.; Rauramaa, R.; Riaz, M.; Robino, A.; Rueedi, R.; Stringham, H. M.; Takeuchi, F.; van der Most, P. J.; Varga, T. V.; Verweij, N.; Ware, E. B.; Wen, W.; Li, X.; Yanek, L. R.; Amin, N.; Arnett, D. K.; Boerwinkle, E.; Brumat, M.; Cade, B.; Canouil, M.; Chen, Y. I.; Concas, M. P.; Connell, J.; de Mutsert, R.; de Silva, H. J.; de Vries, P. S.; Demirkan, A.; Ding, J.; Eaton, C. B.; Faul, J. D.; Friedlander, Y.; Gabriel, K. P.; Ghanbari, M.; Giulianini, F.; Gu, C. C.; Gu, D.; Harris, T. B.; He J, J.; Heikkinen, S.; Heng, C. K.; Hunt, S. C.; Ikram, M. A.; Jonas, J. B.; Koh, W. P.; Komulainen, P.; Krieger, J. E.; Kritchevsky, S. B.; Kutalik, Z.; Kuusisto, J.; Langefeld, C. D.; Langenberg, C.; Launer, L. J.; Leander, K.; Lemaitre, R. N.; Lewis, C. E.; Liang, J.; Lifelines Cohort Study; Liu, J.; Mägi, R.; Manichaikul, A.; Meitinger, T.; Metspalu, A.; Milaneschi, Y.; Mohlke, K. L.; Mosley, T. H.; Murray, A. D.; Nalls, M. A.; Nang, E. K.; Nelson, C. P.; Nona, S.; Norris, J. M.; Nwuba, C. V.; O'Connell, J.; Palmer, N. D.; Papanicolau, G. J.; Pazoki, R.; Pedersen, N. L.; Peters, A.; Peyser, P. A.; Polasek, O.; Porteous, D. J.; Poveda, A.; Raitakari, O. T.; Rich, S. S.; Risch, N.; Robinson, J. G.; Rose, L. M.; Rudan, I.; Schreiner, P. J.; Scott, R. A.; Sidney, S. S.; Sims, M.; Smith, J. A.; Snieder, H.; Sofer, T.; Starr, J. M.; Sternfeld, B.; Strauch, K.; Tang, H.; Taylor, K. D.; Tsai, M. Y.; Tuomilehto, J.; Uitterlinden, A. G.; van der Ende, M. Y.; van Heemst, D.; Voortman, T.; Waldenberger, M.; Wennberg, P.; Wilson, G.; Xiang, Y. B.; Yao, J.; Yu, C.; Yuan, J. M.; Zhao, W.; Zonderman, A. B.; Becker, D. M.; Boehnke, M.; Bowden, D. W.; de Faire, U.; Deary, I. J.; Elliott, P.; Esko, T.; Freedman, B. I.; Froguel, P.; Gasparini, P.; Gieger, C.; Kato, N.; Laakso, M.; Lakka, T. A.; Lehtimäki, T.; Magnusson, P. K. E.; Oldehinkel, A. J.; Penninx, B. W. J. H.; Samani, N. J.; Shu, X. O.; van der Harst, P.; Van Vliet-Ostaptchouk, J. V.; Vollenweider, P.; Wagenknecht, L. E.; Wang, Y. X.; Wareham, N. J.; Weir, D. R.; Wu, T.; Zheng, W.; Zhu, X.; Evans, M. K.; Franks, P. W.; Gudnason, V.; Hayward, C.; Horta, B. L.; Kelly, T. N.; Liu, Y.; North, K. E.; Pereira, A. C.; Ridker, P. M.; Tai, E. S.; van Dam, R. M.; Fox, E. R.; Kardia, S. L. R.; Liu, C. T.; Province, M. A.; Mook-Kanamori, D. O.; Redline, S.; van Duijn, C. M.; Rotter, J. I.; Kooperberg, C. B.; Gauderman, W. J.; Psaty, B. M.; Rice, K.; Munroe, P. B.; Fornage, M.; Cupples, L. A.; Rotimi, C. N.; Morrison, A. C.; Rao, D. C.; Loos, R. J. F. (Nature Publications, 2019)
    Many genetic loci affect circulating lipid levels, but it remains unknown whether lifestyle factors, such as physical activity, modify these genetic effects. To identify lipid loci interacting with physical activity, we ...
  • de Vries, P. S.; Brown, M. R.; Bentley, A. R.; Sung, Y. J.; Winkler, T. W.; Ntalla, I.; Schwander, K.; Kraja, A. T.; Guo, X.; Franceschini, N.; Cheng, C. Y.; Sim, X.; Vojinovic, D.; Huffman, J. E.; Musani, S. K.; Li, C.; Feitosa, M. F.; Richard, M. A.; Noordam, R.; Aschard, H.; Bartz, T. M.; Bielak, L. F.; Deng, X.; Dorajoo, R.; Lohman, K. K.; Manning, A. K.; Rankinen, T.; Smith, A. V.; Tajuddin, S. M.; Evangelou, E.; Graff, M.; Alver, M.; Boissel, M.; Chai, J. F.; Chen, X.; Divers, J.; Gandin, I.; Gao, C.; Goel, A.; Hagemeijer, Y.; Harris, S. E.; Hartwig, F. P.; He, M.; Horimoto, A. R. V. R.; Hsu, F. C.; Jackson, A. U.; Kasturiratne, A.; Komulainen, P.; Kühnel, B.; Laguzzi, F.; Lee, J. H.; Luan, J.; Lyytikäinen, L. P.; Matoba, N.; Nolte, I. M.; Pietzner, M.; Riaz, M.; Said, M. A.; Scott, R. A.; Sofer, T.; Stancáková, A.; Takeuchi, F.; Tayo, B. O.; van der Most, P. J.; Varga, T. V.; Wang, Y.; Ware, E. B.; Wen, W.; Yanek, L. R.; Zhang, W.; Zhao, J. H.; Afaq, S.; Amin, N.; Amini, M.; Arking, D. E.; Aung, T.; Ballantyne, C.; Boerwinkle, E.; Broeckel, U.; Campbell, A.; Canouil, M.; Charumathi, S.; Chen, Y. I.; Connell, J. M.; de Faire, U.; de Las Fuentes, L.; de Mutsert, R.; de Silva, H. J.; Ding, J.; Dominiczak, A. F.; Duan, Q.; Eaton, C. B.; Eppinga, R. N.; Faul, J. D.; Fisher, V.; Forrester, T.; Franco, O. H.; Friedlander, Y.; Ghanbari, M.; Giulianini, F.; Grabe, H. J.; Grove, M. L.; Gu, C. C.; Harris, T. B.; Heikkinen, S.; Heng, C. K.; Hirata, M.; Hixson, J. E.; Howard, B. V.; Ikram, M. A.; InterAct Consortium; Jr. Jacobs, D. R.; Johnson, C.; Jonas, J. B.; Kammerer, C. M.; Katsuya, T.; Khor, C. C.; Kilpeläinen, T. O.; Koh, W. P.; Koistinen, H. A.; Kolcic, I.; Kooperberg, C.; Krieger, J. E.; Kritchevsky, S. B.; Kubo, M.; Kuusisto, J.; Lakka, T. A.; Langefeld, C. D.; Langenberg, C.; Launer, L. J.; Lehne, B.; Lemaitre, R. N.; Li, Y.; Liang, J.; Liu, J.; Liu, K.; Loh, M.; Louie, T.; Mägi, R.; Manichaikul, A. W.; McKenzie, C. A.; Meitinger, T.; Metspalu, A.; Milaneschi, Y.; Milani, L.; Mohlke, K. L.; Jr. Mosley, T. H.; Nelson, C. P.; Mukamal, K. J.; Nalls, M. A.; Nauck, M.; Sotoodehnia, N.; O'Connell, J. R.; Palmer, N. D.; Pazoki, R.; Pedersen, N. L.; Peters, A.; Peyser, P. A.; Polasek, O.; Poulter, N.; Raffel, L. J.; Raitakari, O. T.; Reiner, A. P.; Rice, T. K.; Rich, S. S.; Robino, A.; Robinson, J. G.; Rose, L. M.; Rudan, I.; Schmidt, C. O.; Schreiner, P. J.; Scott, W. R.; Sever, P.; Shi, Y.; Sidney, S.; Sims, M.; Smith, B. H.; Smith, J. A.; Snieder, H.; Starr, J. M.; Strauch, K.; Tan, N.; Taylor, K. D.; Teo, Y. Y.; Tham, Y. C.; Uitterlinden, A. G.; van Heemst, D.; Vuckovic, D.; Waldenberger, M.; Wang, L.; Wang, Y.; Wang, Z.; Wei, W. B.; Williams, C.; Sr Wilson, G.; Wojczynski, M. K.; Yao, J.; Yu, B.; Yu, C.; Yuan, J. M.; Zhao, W.; Zonderman, A. B.; Becker, D. M.; Boehnke, M.; Bowden, D. W.; Chambers, J. C.; Deary, I. J.; Esko, T.; Farrall, M.; Franks, P. W.; Freedman, B. I.; Froguel, P.; Gasparini, P.; Gieger, C.; Horta, B. L.; Kamatani, Y.; Kato, N.; Kooner, J. S.; Laakso, M.; Leander, K.; Lehtimäki, T.; Lifelines Cohort, Groningen,; The Netherlands (Lifelines Cohort Study); Magnusson, P. K. E.; Penninx, B.; Pereira, A. C.; Rauramaa, R.; Samani, N. J.; Scott, J.; Shu, X. O.; van der Harst, P.; Wagenknecht, L. E.; Wang, Y. X.; Wareham, N. J.; Watkins, H.; Weir, D. R.; Wickremasinghe, A. R.; Zheng, W.; Elliott, P.; North, K. E.; Bouchard, C.; Evans, M. K.; Gudnason, V.; Liu, C. T.; Liu, Y.; Psaty, B. M.; Ridker, P. M.; van Dam, R. M.; Kardia, S. L. R.; Zhu, X.; Rotimi, C. N.; Mook-Kanamori, D. O.; Fornage, M.; Kelly, T. N.; Fox, E. R.; Hayward, C.; van Duijn, C. M.; Tai, E. S.; Wong, T. Y.; Liu, J.; Rotter, J. I.; Gauderman, W. J.; Province, M. A.; Munroe, P. B.; Rice, K.; Chasman, D. I.; Cupples, L. A.; Rao, D. C.; Morrison, A. C. (School of Hygiene and Public Health of Johns Hopkins University,Baltimore., 2019)
    An individual's lipid profile is influenced by genetic variants and alcohol consumption, but the contribution of interactions between these exposures has not been studied. We therefore incorporated gene-alcohol interactions ...
  • Hettiarachchi, S.; Kitnasamy, G.; Gopi, D. (Taylor & Francis, 2019)
    PURPOSE:Parental perceptions are key to the uptake of augmentative and alternative communication (AAC) devices for their children with complex communication needs. This study aimed to explore the perceptions of parents in ...
  • Legido-Quigley, H.; Naheed, A.; de Silva, H. A.; Jehan, I.; Haldane, V.; Cobb, B.; Tavajoh, S.; Chakma, N.; Kasturiratne, A.; Siddiqui, S.; Jafar, T. H. (Public Library of Science:San Francisco, CA ., 2019)
    Hypertension is the leading risk factor for cardiovascular disease and leading cause of premature death globally. In 2008, approximately 40% of adults were diagnosed with hypertension, with more than 1.5 billion people ...
  • Mettananda, S.; Pathiraja, H.; Peiris, R.; Wickramarathne, N.; Bandara, D.; de Silva, U.; Mettananda, C.; Premawardhena, A. (John Wiley, 2019)
    BACKGROUND: Regular blood transfusion therapy still remains the cornerstone in the management of β-thalassemia. Although recommendations are clear for patients with β-thalassemia major, uniform transfusion guidelines are ...
  • Amarasena, H. L. P.; Silva, F. H. D. S.; Tilakaratna, P. M. Y. I.; Jayamanne, S. F.; Ranawaka, U. K. (BioMed Central,London, 2019)
    BACKGROUND:Melioidosis is an infection caused by Burkholderia pseudomallei, which is more prevalent in the tropics and leads to significant morbidity and mortality. It characteristically produces widespread caseous lesions ...
  • Pinto, M. D. P.; Pathiraja, P. D. M.; Ariyarathne, M. H. J. (The College of Surgeons of Sri Lanka, 2011)
    INTRODUCTION: Breast cancer is the most frequently diagnosed life-threatening cancer in women and the leading cause of cancer death among women worldwide. There is no national breast cancer screening programme yet in Sri ...
  • Pinto, M. D. P.; Fernando, R.; Pathmeswaran, A.; Premathilake, M.; Fernando, T.; Edirisinghe, D.; Bandara, D.; Athulugama, N.; Abeysinghe, S. (The College of Surgeons of Sri Lanka, 2011)
    OBJECTIVE: To assess the relationship between dietary goitrogens and the prevalence of goiter. METHODS:A descriptive cross-sectional study on the prevalence of goitre was conducted involving all areas of the ...
  • Liyanage, C.; Nawaratne, M.; Pathirana, A.; Gunasekara, D.; iPranahewa, L.; Prasad, R.; Wijeratne, T.; Bogammana, M.; Wijesooriya, R.; Siriwardhana, R. (The College of Surgeons of Sri Lanka, 2012)
    INTRODUCTION: Hllar-Cholangio-carcinomas (HCC) are aggressive tumours with a dismal prognosis. The general tendency amongst all specialities is to palliate them. As response to adjuvant therapy is marginal we have ...
  • Liyanage, C.; Keragala, T.; Femandopulle, N.; Nawaratne, N. M. M. (The College of Surgeons of Sri Lanka, 2012)
    INTRODUCTION: Periampullary duodenal diverticuli (PDD) are extra luminal mucosal out pouching of duodenum arising adjacent to or containing the ampulla of Vater or intraluminal portion of CBD . Juxta-papillary duodenal ...
  • Markar, S. (The College of Surgeons of Sri Lanka, 2012)
    INTRODUCTION: The aim of this study was to compare management approaches and clinical outcomes of acute appendicitis in Sri Lanka and the United Kingdom. MATERIALS AND METHODS: Data was collected prospectively from 200 ...
  • Keragala, T. S.; Deen, K. I.; Liyanage, C. A. H. (The College of Surgeons of Sri Lanka, 2011)
    INTRODUCTION:Effective clinical handover ensures continuity of patient care. There is little evidence regarding clinical handovers in the Sri Lankan setting assesses the effect of standardised pro-forma on clinical data ...
  • Chandrasinghe, P. C.; Ediriweera, E. P. D. S.; Kumarage, S. K.; Deen, K. I. (The College of Surgeons of Sri Lanka, 2012)
    INTRODUCTION: Serum albumin is a marker of nutrition and inflammation. It has recently emerged as a predictor of outcome after surgery for rectal cancer. Our aim was to evaluate if pre-operative serum albumin would predict ...
  • Sabaratnam, V. Y.; Deen, K. I.; Kim, J. H. (The College of Surgeons of Sri Lanka and SAARC Surgical Care Society, 2003)
    INTRODUCTION: Management of left colon obstruction either by primary anastomosis or by diversion almost always requires decompression and lavage of the colon. This will facilitate colonic mobilization primary anastomosis, ...
  • Siriwardana, P. N.; Rathnayaka, G.; Deen, K. I. (The College of Surgeons of Sri Lanka and SAARC Surgical Care Society, 2003)
    INTRODUCTION: The quality of a histopathology report in CRC will determine prognosis and the need for adjuvant therapy. OBJECTIVE: To evaluate the completeness of pathology reports in colorectal cancer.METHODS: ...
  • Hewavisenthi, S. J.; Obrien, J.; Powe, D.; Zaitoun, A. M. (The College of Surgeons of Sri Lanka and SAARC Surgical Care Society, 2003)
    INTRODUTION: The growth and development of tumours depend on the balance between cell proliferation and cell death apoptosis. Since the adenoma - carcinoma sequence is well established in colorectal ...
  • Sabaratnam, V. Y.; Ariyaratne, M. H. J. (The College of Surgeons of Sri Lanka and SAARC Surgical Care Society, 2003)
    INTRODUCTION: Flexible cystoscopy is performed as an out patient procedure. OBJECTIVE: To audit the our experience of out patient flexible cystoscopy. Methods: Patients presenting with lower urinary symptoms (haematuria, ...
  • De Silva, M.; Selliah, S.; Thabrew, I. (The College of Surgeons of Sri Lanka and SAARC Surgical Care Society, 2003)
    INTRODUCTION: Although alcohol abuse is a common cause of pancreatic calcification in the west, a non-alcoholic form called Tropical caicific Pancreatitis (TCP) is recognized in Asian countries.OBJECTIVE: ...
  • Siva, S.; De Silva, M.; Thabrew, I. (The College of Surgeons of Sri Lanka and SAARC Surgical Care Society, 2003)
    INTRODUCTION: Presence of calcification in the pancreas confirms the diagnosis of Chronic Pancreatitis. In the developing countries, a non alcoholic form referred to as Tropical Calcific Pancreatitis ...
  • Sabaratnam, V. Y.; Rathnayake, G.; Deen, K. I. (The College of Surgeons of Sri Lanka and SAARC Surgical Care Society, 2003)
    INTRODUCTION: Traditionally, suture rectopexy has been combined with sigmoid resection for rectal prolapse to prevent postoperative constipation. Furthermore, preservation of lateral ligaments will not result in ...

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