Assessing the synaptic transmission speed (ms) and action potential frequency (Hz) of water in relation to its behaviour in theoretical and computational neuroscience field
| dc.contributor.author | Adiaha, M. S. | |
| dc.date.accessioned | 2025-11-24T08:01:14Z | |
| dc.date.issued | 2025 | |
| dc.description.abstract | The study quantified water concentration (%) effects on synaptic transmission speed (ms) and action potential (AP) frequency (Hz) in silico. NEURON-simulated pyramidal neuron under controlled water levels (40–100%) was undertaken. Linear regression (SciPy) was applied to analyzed relationships. The result indicated that synaptic delay increased linearly with water reduction: slope = -0.012 ms/% (R²=0.99, F(1,2)=172.5, p <0.01). AP frequency decreased linearly: slope = -0.225 Hz/% (R² = 0.99, F(1,2) = 452.3, p <0.01). Mean ± SEM at 70% water: synaptic delay = 1.43±0.129 ms; AP frequency = 39.75±2.07 Hz. The study concluded that; water concentration directly governs neural signaling velocity and firing rates with near-perfect linear predictability. | |
| dc.identifier.citation | Adiaha, M. S. (2025). Assessing the synaptic transmission speed (ms) and action potential frequency (Hz) of water in relation to its behaviour in the theoretical and computational neuroscience field. Journal of Multidisciplinary and Translational Research (JMTR), 10(1), 25–32. https://doi.org/10.4038/jmtr.v10i1.97 | |
| dc.identifier.uri | http://repository.kln.ac.lk/handle/123456789/30579 | |
| dc.publisher | Journal of Multidisciplinary and Translational Research (JMTR) | |
| dc.subject | Water | |
| dc.subject | computational neuroscience | |
| dc.subject | theoretical neuroscience | |
| dc.subject | synaptic transmission | |
| dc.subject | ion transport | |
| dc.subject | neural networks | |
| dc.title | Assessing the synaptic transmission speed (ms) and action potential frequency (Hz) of water in relation to its behaviour in theoretical and computational neuroscience field | |
| dc.type | Article |