Significance of polymorphonuclear leucocytes with drumstic in malaria positive and normal patient in Ekiti State South Western, Nigeria

Abstract

Introduction: Malaria is estimated to cause about millions cases with high death rate recorded annually. Sickle cell, B blood group and duff blood antigens have selective advantage against malaria infection caused by Plasmodium falciparum and vivax respectively. Objective: To study the effect of Polymorphonuclear Leucocytes with Drumstic (PMND) in immunity to malaria infection Methodology: Three selected local government areas in South West Nigeria were sampled. When the results obtained with the malaria negative female population compared with malaria positive population by subjected to Chi-square statistical analysis to verify whether the observed results has significant difference. Results: The percentage of normal individual female positive for PMND was 4% while none of the male patient screened was positive for PMND. When the results obtained with the malaria negative female population compared with malaria positive population by subjected to Chi-square statistical analysis to verify whether the observed results has significant difference. The result shown that there was no significant difference (X2 (α = 0.05) (1)< X2 cal) as the value positive for PMND in malaria positive compare with malaria negative female patient was only 5.26%. Discussion: This study shows that PMND have no immunity role to play in malaria infection.