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Ambulatory blood pressure levels in individuals with uncontrolled clinic hypertension across Bangladesh, Pakistan, and Sri Lanka

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dc.contributor.author Zhu, A.
dc.contributor.author Ostbye, T.
dc.contributor.author Naheed, A.
dc.contributor.author de Silva, H.A.
dc.contributor.author Jehan, I.
dc.contributor.author Gandhi, M.
dc.contributor.author Chakma, N.
dc.contributor.author Kasturiratne, A.
dc.contributor.author Samad, Z.
dc.contributor.author Jafar, T.H.
dc.date.accessioned 2024-03-11T09:18:50Z
dc.date.available 2024-03-11T09:18:50Z
dc.date.issued 2024
dc.identifier.citation Journal of Clinical Hypertension(Greenwich).2024;26(4):391-404.(Epub 2024 Mar 7.) en_US
dc.identifier.issn 1524-6175 (Print)
dc.identifier.issn 1751-7176 (Electronic)
dc.identifier.uri http://repository.kln.ac.lk/handle/123456789/27701
dc.description Indexed in MEDLINE en_US
dc.description.abstract Hypertension is a leading risk factor for cardiovascular disease in South Asia. The authors aimed to assess the cross-country differences in 24-h ambulatory, daytime, and nighttime systolic blood pressure (SBP) among rural population with uncontrolled clinic hypertension in Bangladesh, Pakistan, and Sri Lanka. The authors studied patients with uncontrolled clinic hypertension (clinic BP ≥ 140/90 mmHg) who underwent ambulatory blood pressure monitoring (ABPM) during the baseline assessment as part of a community-based trial. The authors compared the distribution of ABPM profiles of patients across the three countries, specifically evaluating ambulatory SBP levels with multivariable models that adjusted for patient characteristics. Among the 382 patients (mean age, 58.3 years; 64.7% women), 56.5% exhibited ambulatory hypertension (24-h ambulatory BP ≥ 130/80 mmHg), with wide variation across countries: 72.6% (Bangladesh), 50.0% (Pakistan), and 51.0% (Sri Lanka; P < .05). Compared to Sri Lanka, adjusted mean 24-h ambulatory, daytime, and nighttime SBP were higher by 12.24 mmHg (95% CI 4.28-20.20), 11.96 mmHg (3.87-20.06), and 12.76 mmHg (4.51-21.01) in Bangladesh, separately. However, no significant differences were observed between Pakistan and Sri Lanka (P > .05). Additionally, clinic SBP was significantly associated with 24-h ambulatory (mean 0.38, 95% CI 0.28-0.47), daytime (0.37, 0.27-0.47), and nighttime SBP (0.40, 0.29-0.50) per 1 mmHg increase. The authors observed substantial cross-country differences in the distribution of ABPM profiles among patients with uncontrolled clinic hypertension in rural South Asia. The authors findings indicated the need to incorporate 24-h BP monitoring to mitigate cardiovascular risk, particularly in Bangladesh. en_US
dc.language.iso en en_US
dc.publisher Wiley en_US
dc.subject South Asia en_US
dc.subject Ambulatory blood pressure monitor en_US
dc.subject Uncontrolled clinic hypertension en_US
dc.title Ambulatory blood pressure levels in individuals with uncontrolled clinic hypertension across Bangladesh, Pakistan, and Sri Lanka en_US
dc.type Article en_US


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