Medicine

 

This repository contains the published and unpublished research of the Faculty of Medicine by the staff members of the faculty

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  • Bundy, D.A.P.; Appleby, L.J.; Bradley, M.; Croke, K.; Hollingsworth, T.D.; Pullan, R.; Turner, H.C.; de Silva, N. (London : Academic Press, 2018)
    For more than 100 years, countries have used mass drug administration as a public health response to soil-transmitted helminth infection. The series of analyses published as Disease Control Priorities is the World Bank's ...
  • Sung, Y.J.; Winkler, T.W.; de Las Fuentes, L.; Bentley, A.R.; Brown, M.R.; Kraja, A.T.; Schwander, K.; Ntalla, I.; Guo, X.; Franceschini, N.; Lu, Y.; Cheng, C.Y.; Sim, X.; Vojinovic, D.; Marten, J.; Musani, S.K.; Li, C.; Feitosa, M.F.; Kilpelainen, T.O.; Richard, M.A.; Noordam, R.; Aslibekyan, S.; Aschard, H.; Bartz, T.M.; Dorajoo, R.; Liu, Y.; Manning, A.K.; Rankinen, T.; Smith, A.V.; Tajuddin, S.M.; Tayo, B.O.; Warren, H.R.; Zhao, W.; Zhou, Y.; Matoba, N.; Sofer, T.; Alver, M.; Amini, M.; Boissel, M.; Chai, J.F.; Chen, X.; Divers, J.; Gandin, I.; Gao, C.; Giulianini, F.; Goel, A.; Harris, S.E.; Hatwig, F.P.; Horimoto, A.R.V.R.; Hsu, F.C.; Jackson, A.U.; Kahonen, M.; Kasturiratne, A.; Kuhnel, B.; Leander, K.; Lee, W.J.; Lin, K.H.; an Luan, J.; McKenzie, C.A.; Meian, H.; Nelson, C.P.; Rauramaa, R.; Schupf, N.; Scott, R.A.; Sheu, W.H.H.; Stancakova, A.; Takeuchi, F.; van der Most, P.J.; Varga, T.V.; Wang, H.; Wang, Y.; Ware, E.B.; Weiss, S.; Wen, W.; Yanek, L.R.; Zhang, W.; Zhao, J.H.; Afag, S.; Alfred, T.; Amin, N.; Arking, D.; Aung, T.; Barr, R.G.; Bielak, L.F.; Boerwincle, E.; Bottinger, E.P.; Braund, P.S.; Brody, J.A.; Broeckel, U.; Cabrera, C.P.; Cade, B.; Caizheng, Y.; Campbell, A.; Canouil, M.; Chakravarti, A.; CHARGE Neurology Working Group; Chauhan, G.; Christensen, K.; Cocca, M.; COGENT-Kidney Consortium; Collins, F.S.; Connel, J.M.; de Mutsert, R.; de Silva, H.J.; Debette, S.; Dorr, M.; Duan, Q.; Eaton, C.B.; Ehret, G.; Evangelou, E.; FAul, J.D.; Fisher, V.A.; Forouhi, N.G.; Franco, O.H.; Friedlander, Y.; Gao, H.; GIANT Consortium; Gigante, B.; Graff, M.; Gu, C.C.; Gu, D.; Gupta, P.; Hagenaars, S.P.; Harris, T.B.; He, J.; Heikkinen, S.; Heng, C.K.; Hirata, M.; Hofman., A.; Howard, B.V.; Hunt, S.; Irvin, M.R.; Jia, Y.; Joehanes, R.; Justice, A.E.; Katsuya, T.; Kaufman, J,; Kerrison, N.D.; Khor, C.C.; Koh, W.P.; Koistinen, H.A.; Komulainen, P.; Kooperberg, C.; Krieger, J.E.; Kubo, M.; Kuusisto, J.; Lanefeld, C.D.; Langenberg, C.; Launer, L.J.; Lehne, B.; Lewis, C.E.; Li, Y.; Lifelines Cohort Study; Lim, S.H.; Lin, S.; Liu, C.T.; Liu, J.; Liu, J.; Liu, K.; Liu, Y.; Loh, M.; Lohmann, K.K.; Long, J.; Louie, T.; Magi, R.; Mahajan, A.; Meitinger, T.; Metspalu, A.; Milani, L.; Momozawa, Y.; Morris, A.P.; Mosley, T.H.Jr.; Munson, P.; Murray, A.D.; Nalls, M.A.; Nasri, U.; Norris, J.M.; North, K.; Ogunniyi, A.; Padmanabhan, S.; Palmas, W.R.; Palmer, N.D.; Pankow, J.S.; Pedersen, N.L.; Peters, A.; Peyser, P.A.; Polasek, O.; Raitakari, O.T.; Renstrom, F.; Rice, T.K.; Ridker, P.M.; Robino, A.; Robinson, J.G.; Rose, L.M.; Rudan, I.; Salako, B.L.; Sandow, K.; Schmidt, C.O.; Schreiner, P.J.; Scott, W.R.; Seshadri, S.; Sever, P.; Sitlani, C.M.; Smith, J.A.; Snieder, H.; Starr, J.M.; Strauch, K.; Tang, H.; Taylor, K.D.; Teo, Y.Y.; Tham, Y.C.; Uitterlineden, A.G.; Waldenberger, M.; Wang, L.; Wang, Y.X.; Wei, W.B.; Williams, C.; Wilson, G.; Wojczynski, M.K.; Yao, J.; Yuan, J.M.; Zonderman, A.B.; Becker, D.M.; Boehnke, M.; Bowden, D.W.; Chambers, J.C.; Chen, Y.I.; de Faire, U.; Deary, I.J.; Esco, T.; Farrall, M.; Forrester, T.; Franks, P.W.; Freedman, B.I.; Froguel, P.; Gasparini, P.; Gieger, C.; Horta, B.L.; Hung, Y.J.; Jonas, J.B.; Kato, N.; Kooner, J.S.; Laakso, M.; Lehtimaki, T.; Liang, K.W.; Magnusson, P.K.E.; Newman, A.B.; Oldehinkel, A.J.; Pereira, A.C.; Redline, S.; Rettig, R.; Samani, N.J.; Scott, J.; Shu, X.O.; van der Harst, P.; Wagenknecht, L.E.; Wareham, N.J.; Watkins, H.; Weir, D.R.; Wickremasinghe, A.R.; Wu, T.; Zheng, W.; Kamatani, Y.; Laurie, C.C.; Bouchard, C.; Cooper, R.S.; Evans, M.K.; Gudnason, V.; Kardia, S.L.R.; Kritchevsky, S.B.; Levy, D.; O'Connell, J.R.; Psaty, B.M.; van Dam, R.M.; Sims, M.; Arnett, D.K.; Mook-Kanamori, D.O.; Kelly, T.N.; Fox, E.R.; Hayward, C.; Fornage, M.; Rotimi, C.N.; Province, M.A.; van Dujin, C.M.; Tai, E.S.; Wong, T.Y.; Loos, R.J.F.; Reiner, A.P.; Rotter, J.I.; Zhu, X.; Bierut, L.J.; Gauderman, W.J.; Caulfield, M.J.; Elliott, P.; Rice, K.; Munroe, P.B.; Morrison, A.C.; Cupples, L.A.; Rao., D.C.; Chasman, D.I. (University of Chicago Press, 2018)
    Genome-wide association analysis advanced understanding of blood pressure (BP), a major risk factor for vascular conditions such as coronary heart disease and stroke. Accounting for smoking behavior may help identify BP ...
  • Ranasinghe, N.; Devanarayana, N.M.; Rajindrajith, S.; Perera, M.S.; Nishanthinie, S.; Warnakulasuriya, T.; de Zoysa, P.T. (BioMed Central, 2018)
    BACKGROUND: Chronic abdominal pain is a common worldwide problem and known to be associated with psychological problems. This study evaluated the association between abdominal pain-predominant functional gastrointestinal ...
  • Siriwardhana, D.D.; Hardoon, S.; Rait, G.; Weerasinghe, M.C.; Walters, K.R. (BMJ Publishing Group Ltd, 2018)
    OBJECTIVE: To systematically review the research conducted on prevalence of frailty and prefrailty among community-dwelling older adults in low-income and middle-income countries (LMICs) and to estimate the pooled prevalence ...
  • Karuppiah, D.; Cooray, M.S.A.; Somasundaram, N.; Ediriweera, D.S. (2018)
    INTRODUCTION: Cushing’s syndrome (CS) may be unrecognized in patients with diabetes. There is no consensus on routine screening for CS in patients with type 2 diabetes (T2DM). Aim of the study was to evaluate the prevalence ...
  • Carter, P.; Alifrangis, C.; Cereser, B.; Chandrasinghe, P.; Belluz, L.D.B.; Herzog, T.; Levitan, J.; Moderau, N.; Schwartzberg, L.; Tabassum, N.; Wen, J.; Krell, J.; Stebbing, J. (Impact Journals, 2018)
    We evaluated the effect of tailoring treatments based on predictions informed by tumor molecular profiles across a range of cancers, using data from Caris Life Sciences. These included breast carcinoma, colorectal ...
  • Rajindrajith, S.; Zeevenhooven, J.; Devanarayana, N.M.; Perera, B.J.C.; Benninga, M.A. (Taylor & Francis, 2018)
    Chronic abdominal pain is a common problem in pediatric practice. The majority of cases fulfill the Rome IV criteria for functional abdominal pain disorders (FAPDs). At times, these disorders may lead to rather serious ...
  • Rodrigo, R.; Allen, A.; Manamperi, A.; Perera, L.; Fisher, C.A.; Allen, S.; Weatherall, D.J.; Premawardhena, A. (Academic Press, 2018)
    Iron deficiency complicates the use of red cell indices to screen for carriers of haemoglobin variants in many populations. In a cross sectional survey of 7526 secondary school students from 25 districts of Sri Lanka, 1963 ...
  • Jayamanne, C.; Fernando, L.; Mettananda, S. (BioMed Central, 2018)
    BACKGROUND: Foot drop is a disabling clinical condition with multiplicity of causes, which requires detailed evaluation to identify the exact aetiology. Here, we report an extremely rare cause of foot drop in a child, which ...
  • Morales-Roselló, J.; Dias, T.; Khalil, A.; Fornes-Ferrer, V.; Ciammella, R.; Gimenez Roca, L.; Perales-Marín, A.; Thilaganathan, B. (John Wiley & Sons, 2018)
    OBJECTIVE: The main aim of this study was to investigate the influence of ethnicity, fetal gender and placental dysfunction on birth weight (BW) in term fetuses of South Asian and Caucasian origin. METHODS: This was a ...
  • Somarathne, M.B.C.L.; Gunawardena, Y.I.N.S.; Chandrasekharan, N.V.; Dassanayake, R.S. (Academic Press, 2018)
    Despite the differences of the host, parasitic nematodes may share commonalities in their parasitizing genes. Setaria digitata novel protein (SDNP) is such an entity which is parasitic nematode-specific and having sequence ...
  • Ediriweera, D.S.; Dilina, N.; Saparamadu, V.; Fernando, I.; Kurukulasuriya, B.; Fernando, D.; Kurera, J. (Biomed Central, 2018)
    OBJECTIVE: Aspirin is a commonly used medicine for primary and secondary prevention of cardiovascular diseases. It is an acidic medicine associated with gastric irritation and acid reflux, which in turn can lead to low ...
  • Mettananda, S.; Higgs, D.R. (Elsevier Health Science, 2018)
    Thalassemia is a disorder of hemoglobin characterized by reduced or absent production of one of the globin chains in human red blood cells with relative excess of the other. Impaired synthesis of β-globin results in ...
  • Weerasinghe, M.; Konradsen, F.; Eddleston, M.; Pearson, M.; Jayamanne, S.; Gunnell, D.; Hawton, K.; Agampodi, S. (BioMed Central, 2018)
    BACKGROUND: In South Asia, up to 20% of people ingesting pesticides for self-poisoning purchase the pesticide from a shop with the sole intention of self-harm. Individuals who are intoxicated with alcohol and/or non-farmers ...
  • Carter, P.; Alifrangis, C.; Cereser, B.; Chandrasinghe, P.; Del Bel Belluz, L.; Fotopoulou, C.; Frilling, A.; Herzog, T.; Moderau, N.; Tabassum, N.; Krell, J.; Stebbing, J. (Impact Journals, 2017)
    Tumor molecular profiling has enabled selection of targeted therapies in a host of solid tumors. Here we used a retrospective clinical cohort, to evaluate the benefit of tailoring treatments for female genital tract ...
  • Udayanga, L.; Gunathilaka, N.; Iqubal, M.C.M.; Pahalagedara, K.; Amarasinghe, U.S.; Abeyewickreme, W. (BioMed Central, 2018)
    BACKGROUND: Socio-economic, demographic factors and Knowledge Attitude Practices (KAPs) have been recognized as critical factors that influence the incidence and transmission of dengue epidemics. However, studies that ...
  • de Silva, S.T.; Niriella, M.A; Kasturiratne, A.; Kottahachchi, D.; Ranawaka, U.K.; Dasanayaka, A.; de Silva, A.P.; Pathmeswaran, P.; Wickremasinghe, R.; Kato, N.; de Silva, J. (European Association for the Study of Diabetes, 2017)
    BACKGROUND AND AIMS In 2007, we reported a 38.9% prevalence of metabolic syndrome (MetS) in an urban, adult population. Published data on incident MetS from South Asia is lacking. This study investigated the incidence and ...
  • Dias, T.; Niriella, M.; de Silva, S.; Motha, C.; Palihawadana, T.S.; Ediiweera, D.; de Silva, J. (Wiley Publishing, 2017)
    OBJECTIVES: Metabolic syndrome (MetS) has been recognised as a risk factor for malignancies. The aim of this study was to evaluate the association of MetS and risk of endometrial carcinoma (EC), by measuring endometrial ...
  • Pieris, V.; Dias, T.; Palihawadana, T.S.; de Silva, J. (Wiley Publishing, 2016)
    OBJECTIVES : To describe the variations in endometrial thickness and the ovarian volume among peri and postmenopausal women. METHODS : A cross-sectional analysis was done in a study population of a longitudinal study. This ...
  • Fernando, M.P.; Perera, P.J.; Muthukumarana, O.J.; Uyangoda, K. (Sri Lanka Medical Association, 2017)
    No Abstract Available

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