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Case report of an infant with congenital mesoblastic nephroma leading to pulmonary metastasis

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dc.contributor.author Athapathu, A.S.
dc.contributor.author Wijayawardhana, S.M.
dc.contributor.author Meegoda, J.
dc.contributor.author Gunaratne, S.A.
dc.contributor.author Somathilaka, M.
dc.contributor.author Chang, K.T.E.
dc.contributor.author Wickramasinghe, P.
dc.date.accessioned 2023-12-28T04:04:53Z
dc.date.available 2023-12-28T04:04:53Z
dc.date.issued 2023
dc.identifier.citation SAGE Open Medical Case Reports.2023;11:2050313X231220826 en_US
dc.identifier.issn 2050-313X (Electronic)
dc.identifier.uri http://repository.kln.ac.lk/handle/123456789/27158
dc.description Not Indexed in MEDLINE en_US
dc.description.abstract Congenital mesoblastic nephroma is considered a tumour with favourable clinical behaviour with only few reported cases of metastases. We report an infant who underwent complete resection and later developed pulmonary metastasis. Ten-month-old baby girl initially presented at 3 weeks of age with macroscopic haematuria, hypertension and a lumbar mass. Contrast-enhanced computed tomography revealed a tumour arising from the left kidney without local invasion or metastasis. She underwent left nephrectomy. Immunohistochemistry confirmed a cellular type of congenital mesoblastic nephroma. At 10 months, she presented with difficulty in breathing. Contrast-enhanced computed tomography revealed an opacity in the right hemi-thorax. Histology of lung mass was suggestive of deposits from the previously excised mesoblastic nephroma. She developed a right-sided haemothorax and succumbed. This case report highlights the fact that even though congenital mesoblastic nephromas are considered tumours with favourable clinical behaviour, they can present later with distant metastasis. Therefore, clinicians need to be aware of this rare malignant potential and adhere to meticulous follow-up protocols. en_US
dc.language.iso en en_US
dc.publisher Sage Publishing en_US
dc.subject Congenital mesoblastic nephroma en_US
dc.subject infantile tumour en_US
dc.subject lung metastasis en_US
dc.subject malignant potential en_US
dc.title Case report of an infant with congenital mesoblastic nephroma leading to pulmonary metastasis en_US
dc.type Article en_US


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