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Disseminated tuberculosis presenting as meningitis and spondylodiscitis in an immunocompetent adult

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dc.contributor.author Arumugam, J.
dc.contributor.author de Silva, S.
dc.date.accessioned 2023-10-06T06:30:44Z
dc.date.available 2023-10-06T06:30:44Z
dc.date.issued 2023
dc.identifier.citation Asian Pacific Journal of Tropical Medicine.2023;16(6):284-286 en_US
dc.identifier.issn 19957645
dc.identifier.uri http://repository.kln.ac.lk/handle/123456789/26722
dc.description Not Indexed en_US
dc.description.abstract Rationale: Disseminated tuberculosis involves the central nervous system in up to a third of cases. However, meningitis and spondylodiscitis due to miliary tuberculosis rarely occur together, particularly in the immuno-competent population. Patient concerns: A 37-year-old immunocompetent male presented with altered level of consciousness for one week and lower back pain with evening pyrexia for one month. Examination revealed spastic paraplegia and left hemiparesis. Diagnosis: Disseminated tuberculosis presenting with meningitis and spondylodiscitis. Interventions: Category I anti-tuberculous therapy with a tapering regimen of intravenous dexamethasone was administered. Outcomes: There was clinical improvement after nine months of treatment. Lessons: Tuberculosis may present with atypical clinical manifestations. Contrast enhanced computed tomography scan or magnetic resonance imaging combined with histopathological features, a high index of suspicion and clinical improvement with anti-tuberculous treatment can confirm the diagnosis in the absence of microbiological evidence, especially in extrapulmonary tuberculosis. en_US
dc.language.iso en en_US
dc.publisher Medknow Publications en_US
dc.subject Disseminated tuberculosis en_US
dc.subject Immunocompetent en_US
dc.subject Spondylodiscitis en_US
dc.subject Meningitis en_US
dc.subject Miliary tuberculosis en_US
dc.title Disseminated tuberculosis presenting as meningitis and spondylodiscitis in an immunocompetent adult en_US
dc.type Article en_US


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