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The incidence and risk factors of postpartum diabetes in women from Bangladesh, India and Sri Lanka (South Asia) with prior gestational diabetes mellitus: Results from the LIVING study

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dc.contributor.author Gupta, Y.
dc.contributor.author Kapoor, D.
dc.contributor.author Lakshmi, J.K.
dc.contributor.author Praveen, D.
dc.contributor.author Santos, J.A.
dc.contributor.author Billot, L.
dc.contributor.author Naheed, A.
dc.contributor.author de Silva, H.A.
dc.contributor.author Gupta, I.
dc.contributor.author Farzana, N.
dc.contributor.author John, R.
dc.contributor.author Ajanthan, S.
dc.contributor.author Bhatla, N.
dc.contributor.author Desai, A.
dc.contributor.author Pathmeswaran, A.
dc.contributor.author Prabhakaran, D.
dc.contributor.author Teede, H.
dc.contributor.author Zoungas, S.
dc.contributor.author Patel, A.
dc.contributor.author Tandon, N.
dc.contributor.author LIVING Collaborative Group
dc.date.accessioned 2023-09-19T08:46:18Z
dc.date.available 2023-09-19T08:46:18Z
dc.date.issued 2023
dc.identifier.citation Diabetes Research and Clinical Practice.2023;204:110893 en_US
dc.identifier.issn 0168-8227 (Print)
dc.identifier.issn 1872-8227 (Electronic)
dc.identifier.uri http://repository.kln.ac.lk/handle/123456789/26535
dc.description Indexed in MEDLINE. en_US
dc.description.abstract AIM: To study, the incidence and risk factors for postpartum diabetes (DM), in women with gestational diabetes mellitus (GDM) from South Asia (Bangladesh, India and Sri Lanka), followed for nearly two years after delivery. METHODS: Women with prior GDM diagnosed using IADPSG criteria were invited at 19 centres across Bangladesh, India and Sri Lanka for an oral glucose tolerance test (OGTT) following childbirth, and were enrolled in a randomized controlled trial. The glycaemic category (outcome) was defined from an OGTT based on American Diabetes Association criteria. RESULTS: Participants (n = 1808) recruited had a mean ± SD age of 31.0 ± 5.0 years. Incident DM was identified, between childbirth and the last follow-up, in 310 (17.1 %) women [incidence 10.75/100 person years], with a median follow-up duration of 1.82 years after childbirth. Higher age, lower education status, higher prior pregnancy count, prior history of GDM, family history of DM, and postpartum overweight/obese status were significantly associated with incident DM. Women in Bangladesh had a higher cumulative incidence of DM [16.49/100 person years] than in Sri Lanka [12.74/100 person years] and India [7.21/100 person years]. CONCLUSIONS: A high incidence of DM was found in women with prior GDM in South Asia, with significant variation between countries. Women from Bangladesh had a significantly higher pregnancy count, family history of DM and overweight/obese status, despite having significantly lower age, which could be responsible for their higher rates of DM. Registration of this study: The study was registered with the Clinical Trials Registry of India (CTRI/2017/06/008744), Sri Lanka Clinical Trials Registry (SLCTR/2017/001), and ClinicalTrials.gov (NCT03305939). en_US
dc.language.iso en en_US
dc.publisher Elsevier en_US
dc.subject Diabetes en_US
dc.subject Gestational diabetes en_US
dc.subject Postpartum en_US
dc.subject Risk factors en_US
dc.subject South Asia. en_US
dc.subject Women en_US
dc.title The incidence and risk factors of postpartum diabetes in women from Bangladesh, India and Sri Lanka (South Asia) with prior gestational diabetes mellitus: Results from the LIVING study en_US
dc.type Article en_US


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