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Anaemia due to chronic kidney disease: A cross-sectional analysis from a tertiary referral centre in Sri Lanka

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dc.contributor.author Lakmini, S.
dc.contributor.author Dilhani, N.
dc.contributor.author Luke, W. A. N. V.
dc.contributor.author de Silva, S.
dc.date.accessioned 2023-08-31T05:04:28Z
dc.date.available 2023-08-31T05:04:28Z
dc.date.issued 2023
dc.identifier.citation Journal of the Ceylon College of Physicians.2023;54(1):28–33. en_US
dc.identifier.issn 0379-802X
dc.identifier.uri http://repository.kln.ac.lk/handle/123456789/26526
dc.description Not Indexed en_US
dc.description.abstract INTRODUCTION: Anaemia is a common complication of chronic kidney disease (CKD) that adversely affects cardiovascular health and quality of life. Data on anaemia in Sri Lankan CKD patients is scarce. OBJECTIVES: This study was conducted to assess the prevalence, associations, and treatment response of anaemia in a cohort of patients with CKD. METHODOLOGY: A descriptive cross-sectional study was conducted among consecutive, consenting adult patients with stable CKD attending clinics and wards of the University Medical Unit, Colombo North Teaching Hospital, Ragama. RESULTS: Of 149 patients with CKD (males 57.7%), 70.5% had diabetes, 83.9% had hypertension and 37.6% had ischemic heart disease. Anaemia was present in 90.6% of females and 93% of males. The severity of anaemia was significantly (p=<.05) associated with female gender, advancing CKD stage, diabetes, chronic liver cell disease, being on dialysis, and increasing degree of proteinuria. Of 91 patients investigated for the cause of anaemia, 60.4% had iron deficiency with anaemia of chronic disease, while 27.5% had anaemia of chronic disease based on the blood picture. Of 88 patients with haemoglobin <10g/dl, only 45.4% were on erythropoietin and 56.8% had received blood transfusions. 76.1% of the anaemic patients had hemoglobin below 10g/dL at follow-up despite treatment. CONCLUSIONS: Anaemia was highly prevalent in the CKD cohort with a significant number requiring transfusions. Patients continued to have anaemia despite being treated with nutritional supplements and erythropoietin. en_US
dc.language.iso en en_US
dc.publisher Ceylon College of Physicians en_US
dc.subject Anaemia en_US
dc.subject Chronic kidney disease en_US
dc.subject Iron deficiency en_US
dc.subject erythropoietin en_US
dc.title Anaemia due to chronic kidney disease: A cross-sectional analysis from a tertiary referral centre in Sri Lanka en_US
dc.type Article en_US


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