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An elderly patient with Graves’s disease presenting with hypercalcemia and Gitelman syndrome – A diagnostic challenge

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dc.contributor.author Senevirathne, S.
dc.contributor.author Luke, D.
dc.contributor.author Perera, H.M.M.
dc.date.accessioned 2022-09-12T08:25:46Z
dc.date.available 2022-09-12T08:25:46Z
dc.date.issued 2022
dc.identifier.citation Journal of the Postgraduate Institute of Medicine.2022;9(2):E183 1–4. en_US
dc.identifier.issn 2362-0323
dc.identifier.uri http://repository.kln.ac.lk/handle/123456789/25249
dc.description.abstract A 76-year-old patient with diabetes mellitus, hypertension presented with proximal muscle weakness and diarrhea. She was diagnosed with Graves’disease. She had hypokalemia, metabolic alkalosis, hypomagnesemia, hypercalcemia, hyperkaluria and hypercalciuria. High urine potassium was thought to be due to Gitelman syndrome while high urine calcium excretion settled with normalization of serum calcium. Her serum phosphate, vitamin D level were normal, PTH was suppressed. Screening for myeloma and solid organ malignancies were negative. Plasma renin and aldosterone levels were normal. One month after treatment, she reached normocalcemia and after one year her metabolic abnormalities reversed. The presence of both hypercalcemia and Gitelman syndrome at the same time mimicked Bartter syndrome. Normalization of serum calcium and urine calcium excretion with treatment of thyrotoxicosis lead to the correct diagnosis. en_US
dc.language.iso en en_US
dc.publisher Postgraduate Institute of Medicine University of Colombo en_US
dc.subject Graves’ disease en_US
dc.subject Hypercalcemia en_US
dc.subject Gitelman’s syndrome en_US
dc.title An elderly patient with Graves’s disease presenting with hypercalcemia and Gitelman syndrome – A diagnostic challenge en_US
dc.type Article en_US


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