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Geographic information system (GIS) mapping of lymphatic filariasis endemic areas of Gampaha District, Sri Lanka based on epidemiological and entomological screening

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dc.contributor.author Wijegunawardana, N.D.A.D. en_US
dc.contributor.author Gunawardene, Y.I.N.S. en_US
dc.contributor.author Manamperi, A. en_US
dc.contributor.author Senarathne, H. en_US
dc.contributor.author Abeyewickreme, W. en_US
dc.date.accessioned 2014-10-29T09:40:11Z
dc.date.available 2014-10-29T09:40:11Z
dc.date.issued 2012 en_US
dc.identifier.citation The Southeast Asian Journal of Tropical Medicine and Public Health. 2012; 43(3): pp.557-66 en_US
dc.identifier.uri http://www.tm.mahidol.ac.th/seameo/2012-43-3/03-J09-014_15.pdf
dc.identifier.uri http://repository.kln.ac.lk/handle/123456789/2214
dc.description Indexed in MEDLINE
dc.description.abstract The objective of this study was to develop a site directed geographic information system (GIS) map of lymphatic filariasis (LF) in Gampaha District, Sri Lanka as a guide for targeted control activities. Epidemiological and entomological screening of LF was carried out in nine pre-identified endemic areas in Gampaha District, using night blood screening and pool-screening PCR-ELISA. In total, 1,073 subjects (286 children, 787 adults) from 9 sites were examined. Positive cases were detected at 2 sites, with prevalence rates of 0.5% (Hekiththa) and 3.4% (Peliyagoda); the prevalence of microfilaria (mf) among adult Culex quinquefasciatus mosquitoes surveyed was 30%. The overall prevalence of mosquitoes with L1-L2 larvae of W. bancrofti ranged from 0% to 8.31% using dissection and point estimates of infection prevalence, and ranged from 0 to 32.4% using PCR-ELISA. The largest number of human cases was found at altitudes of 2.5-3.5 min highly populated areas, where transmission appears to have taken place. Questionnaires indicated that limited community awareness of LF may be a reason for the fairly static infection prevalent among the local population. The GIS mapping of LF cases shows a considerable prevalence of LF and marked variability by geographic site in Gampaha.
dc.publisher SEAMEO Regional Tropical Medicine and Public Health Project en_US
dc.subject Filariasis en_US
dc.title Geographic information system (GIS) mapping of lymphatic filariasis endemic areas of Gampaha District, Sri Lanka based on epidemiological and entomological screening en_US
dc.type Article en_US
dc.identifier.department Molecular Medicine Unit en_US
dc.identifier.department Parasitology en_US
dc.creator.corporateauthor SEAMEO Regional Tropical Medicine and Public Health Project en_US


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