• Synthesis of DPA based NNN donor ligands having piperidinyl groups and their platinum complexes towards potent anti-cancer applications 

  Peiris, P. A. L.; Perera, N. T. (Institute of Chemistry Ceylon Adamantane House, Rajagiriya, Sri Lanka., 2020)

  Dipicolylamine (dpa) moiety has received much attention due to its coordination versatility. Our objective is to incorporate piperidinyl groups into the dpa system due to possibility of the piperidinyl group to target ...
• Synthesis of platinum complexes with N^N- sulphonamide ligands towards fluorescence imaging applications 

  Hettige, I. L.; Perera, N.T. (Institute of Chemistry Ceylon Adamantane House, Rajagiriya, Sri Lanka., 2020)

  Ethylenediamine has been used as the backbone to synthesize the novel Pt-N^N complexes. The outstanding binding ability of ethylenediamine allows it to be used in the synthesis of hydrophilic ligand systems, by substituting ...
• Novel fluorescence sensors for determination of Fe3+ in biological systems using sulfonamide derivatives of dipicolylamine ligands 

  Vitharana, K. V. N. N.; Perera, N. T.; Cooray, A.; Deraniyagala, S. P. (Institute of Chemistry Ceylon Adamantane House, Rajagiriya, Sri Lanka., 2020)

  Since fluorescence techniques are highly demanded area in biological species detection, the main objective of this research was to develop real-time, ratiometric fluorescence sensors which can be used for iron cation ...
• Determination of total phenolic content (TPC) of Nymphaea nouchali and Nymphaea pubescens by Folin Ciocalteu method 

  Sundaram, T. M.; Napagoda, M. T.; Wijesekera, K. D.; Wijayaratne, Gaya Bandara (Institute of Chemistry Ceylon Adamantane House, Rajagiriya, Sri Lanka., 2020)

  Nymphaea nouchali (Nil Manel) and Nymphaea pubescens (Olu) are aquatic plants, and have a long history of use as food and folk medicine in many countries. Many phenolic compounds isolated from these two plant species ...
• Phenolic and flavonoid contents and antioxidant activity of methanolic extract of Durio zibethinus Murr. Peels 

  Perera, M. P. J.; Rajapakse, C. S. K. (Institute of Chemistry Ceylon Adamantane House, Rajagiriya, Sri Lanka., 2020)

  Durio zibethinus (durian), known as the King of fruits is one of the most important seasonal fruits in tropical Asia. Even though the edible parts of durian are known to be rich in bioactive compounds, less research has ...
• Detailed evaluation of methylated and acetylated products of cinnamon leaf oil against Aedes aegypti 

  Medagedara, H. K.; Paranagama, P. A.; Gunaratna, Medha J. (Institute of Chemistry Ceylon Adamantane House, Rajagiriya, Sri Lanka., 2020)

  Aedes aegypti is a known vector of several viruses including Yellow fever, Dengue, Chikungunya and Zika virus. Two potential Aedes aegypti mosquito repellents; methyl eugenol and acetyl eugenol were semi-synthesized using ...
• Isolation of cysteine-rich peptides from the deep-sea marine sponge Stryphnus fortis and determination of its antimicrobial effect 

  Kosgahakumbura, K. N. M. L. N; Hettiarachchi, C. M; Jayasinghe, R. P. P. K.; Cárdenas, P.; Gunasekera, S. (Institute of Chemistry Ceylon Adamantane House, Rajagiriya, Sri Lanka., 2020)

  Cysteine-rich peptides are a promising resource for a wide range of pharmacological applications such as development of drug leads and as scaffolds for potential oral drug delivery due to their stable disulfide framework. ...
• Nephelium lappaceum L. peels as a source of phytochemicals with antioxidant and α-amylase inhibitory activities 

  Binuwangi, A. K. D. M.; Rajapakse, C. S. K. (Institute of Chemistry Ceylon Adamantane House, Rajagiriya, Sri Lanka., 2020)

  Nephelium lappaceum L. (Rambutan) is a popular seasonal fruit native to Southeast Asia, enriched in varieties of phytochemicals including vitamins and secondary metabolites. This fruit is consumed fresh, canned, or as a ...
• Development of an herbal drink using Sri Lankan varieties of Sesbania grandiflora and Citrofortunella microcarpa and its antioxidant activity 

  Cooray, P. P. D; Wickramasinghe, P. D. S. U (Institute of Chemistry Ceylon Adamantane House, Rajagiriya, Sri Lanka., 2020)

  A Majority of individuals prefer ready-to-serve (RTS) beverages over preparing herbal drinks due to the busy lifestyle. The current study was focused on the development of a ready-to-serve herbal drink using the pulp of ...
• Exploring bioactive compounds in the endolichenic fungus, Xylaria feejeensis, inhabiting the lichen, Graphis librata, collected from Negombo lagoon, Sri Lanka 

  Gunawardhana, M. H. A. Y.; Wickramarachchi, P. A. S. R.; Weerasinghe, W. R. H.; Paranagama, P. A. (Institute of Chemistry Ceylon Adamantane House, Rajagiriya, Sri Lanka., 2020)

  The accelerating pharmaceutical problem of bacteria growing resistant to existing antibiotics forces the scientific community to search for new antibacterial compounds for antibiotic drug development. Literature reveals ...
• Development of a herbal fairness cream using four medicinal plants 

  Wimalasekera, H. N.; Paranagama, P. A.; Harapathdeniya, S. (Institute of Chemistry Ceylon Adamantane House, Rajagiriya, Sri Lanka., 2020)

  There are reports in the public domain which state that artificially synthesized fairness creams have shown side effects on humans. The purpose of a fairness cream is to get a fairer skin by blocking harmful Ultraviolet ...
• Sodium alginate gel beads with slow-release fertilizer from sea weeds and biostimulants of paddy growth 

  Vadivel, M.; Azees, R. Abdul; Paramabathan, R.; Norrudeen, A. Mohamed; Karthik, N.; Packiaraja, L.; Mohaideen, J. Abbas (Institute of Chemistry Ceylon Adamantane House, Rajagiriya, Sri Lanka., 2020)

  Marine algal seaweed species are often regarded as an underutilized bio resource; many have been used as a source of food, industrial raw materials, and in therapeutic and botanical applications for centuries. Moreover, ...
• Transcriptomic analysis of cyclotides in Sri Lankan Viola betonicifolia 

  Rajendran, Sanjeevan; Slazak, Blazej; Mohotti, Supun; Göransson, Ulf; Hettiarachchi, C. M.; Gunasekera, Sunithi (Institute of Chemistry Ceylon Adamantane House, Rajagiriya, Sri Lanka., 2020)

  Plants belong to Violaceae family are known to contain stable bioactive cyclic peptides known as cyclotides. Eight species of Violaceae plants can be found in Sri Lanka: three from genus Rinorea, three from genus Viola ...
• Association between high sensitivity C-reactive protein and body compositions among community dwelling healthy adults; a cross-sectional study among South East Asians 

  Silva, Eranga Harshani; Wickramatilake, Chandima Madhu; Lekamwasam, Sarath; Mudduwa, L. K. V.; Ubayasiri, Ranjuka Arushana (Institute of Chemistry Ceylon Adamantane House, Rajagiriya, Sri Lanka., 2020)

  High sensitivity C-reactive protein (Hs-CRP) is a predictor of future vascular events. Although studies have shown that Hs-CRP is linked with body fat content, data among South East Asians are inconsistent and sparse. ...
• Cytotoxic effect of a resorcinolic lipid isolated from Mangifera zeylanica in a human cancer cell panel 

  Rathnayaka, Rajitha K.; Samarakoon, Sameera R.; Ediriweera, M. K.; Tennekoon, K. H.; Adhikari, A.; Gunasekara, Dinara S. (Institute of Chemistry Ceylon Adamantane House, Rajagiriya, Sri Lanka., 2020)

  Cancer remains a leading cause of death worldwide. Surgery, chemotherapy, radiotherapy, hormonal therapy and immunotherapy are considered as treatment options for cancer. Plants have played a vital role as a source of ...
• Determination of water quality and suitability in a chronic kidney disease of unknown etiology (CKDu) prevalence area, Sri Lanka 

  Botheju, W. S. M.; Liyanage, Janitha A. (Institute of Chemistry Ceylon Adamantane House, Rajagiriya, Sri Lanka., 2020)

  Chronic Kidney Disease of unknown etiology (CKDu) is a global health obstacle that is presenting as kidney disease in patients who do not show common causative factors, such as diabetes or hypertension. Although the ...
• Bioaccumulation of nephrotoxic metals in rice grains (Oryza sativa) in a CKDu hotspot in Sri Lanka via soil analysis 

  Dayananda, M. D. N. R.; Liyanage, Janitha A. (Institute of Chemistry Ceylon Adamantane House, Rajagiriya, Sri Lanka., 2020)

  Accumulation of nephrotoxic metals in edible crops and associated soil is a major international concerns today which results food safety issues and adverse health risks like CKDu. Soils are considered to be an excellent ...
• Qualitative analysis of heavy metal adsorption by the green synthesized silver nanoparticles 

  Ramanayake, R. A. D. J.; Wickramarachchi, P. A. S. R. (Institute of Chemistry Ceylon Adamantane House, Rajagiriya, Sri Lanka., 2020)

  Silver nanoparticles (AgNPs) have attracted high research interest because of their important applications in antimicrobial, catalysis, and water treatment plants. They display totally new and enhanced properties compared ...
• Effect of a herbal capsule of Coccinia grandis (L.) Voigt (Cucurbitaceae) on lipid profile in patients with newly diagnosed type 2 diabetes mellitus 

  Wasana, K. G. P.; Attanayake, A. P.; Weerarathna, T. P.; Jayatilaka, K. A. P. W. (Institute of Chemistry Ceylon Adamantane House, Rajagiriya, Sri Lanka., 2020)

  Herbal antidiabetic agents have been popular among general population due to their historical usage along with the exceptional therapeutic efficacy. The present study was aimed to determine the effect of a newly developed ...
• The development of novel photodegradable linear low-density polyethylene (LLDPE) and investigation of the antibacterial properties 

  Kandambi, D. P. H.; Mudiyanselage, T. Kuruwita; Udawatte, C. S. (Institute of Chemistry Ceylon Adamantane House, Rajagiriya, Sri Lanka., 2020)

  Plastic does not decompose easily under natural conditions and the need for degradable polyethylene has become an important area of research. In this study, the suitability of using cinnamaldehyde, in its natural and ...

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