Digital Repository
The Impact of empirical hydrocortisone therapy on clinical outcomes in dengue fever: A retrospective chart review
- UoK Repository Home
- →
- Medicine
- →
- Journal/Magazine Articles
- →
- View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.
| dc.contributor.author | de Mel, S. | en |
| dc.contributor.author | Thilakawardana, B.U. | |
| dc.contributor.author | de Mel, P. | |
| dc.contributor.author | de Silva, A.P. | |
| dc.contributor.author | de Mel, C. | |
| dc.contributor.author | Chandrasena, L. | |
| dc.contributor.author | Seneviratne, S.L. | |
| dc.contributor.author | Abeysuriya, V. | |
| dc.date.accessioned | 2020-06-26T05:39:15Z | |
| dc.date.available | 2020-06-26T05:39:15Z | |
| dc.date.issued | 2020 | |
| dc.identifier.citation | Transactions of the Royal Society of Tropical Medicine and Hygiene. 2020;114(8): 632-634. | en_US |
| dc.identifier.issn | 0035-9203 (Print) | |
| dc.identifier.issn | 1878-3503 (Electronic) | |
| dc.identifier.issn | 0035-9203 (Linking) | |
| dc.identifier.uri | http://repository.kln.ac.lk/handle/123456789/21132 | |
| dc.description | Indexed in MEDLINE | en_US |
| dc.description.abstract | BACKGROUND: The role of steroids in dengue infection (DI) remains uncertain. METHODS: A retrospective chart review was conducted on patients ≥18 y of age diagnosed with DI based on positivity for dengue non-structural antigen 1 or immunoglobulin M between October 2017 and November 2018. RESULTS: Hydrocortisone was administered to 106 of 406 patients. DI with warning signs occurred in nine patients (9.5%) in the steroid cohort and eight patients (2.5%) in the non-steroid group. The incidence of severe DI, bleeding and admission duration were similar between the groups. CONCLUSIONS: Our study shows no significant benefit of empirical steroids in DI. KEYWORDS: clinical outcomes; corticosteroids; dengue. | en_US |
| dc.language.iso | en_US | en_US |
| dc.publisher | Oxford University Press | en_US |
| dc.subject | Dengue-drug therapy | en |
| dc.subject | Severe Dengue | |
| dc.subject | Hydrocortisone | |
| dc.subject | Retrospective Studies | |
| dc.subject | Cohort Studies | en |
| dc.title | The Impact of empirical hydrocortisone therapy on clinical outcomes in dengue fever: A retrospective chart review | en_US |
| dc.type | Article | en_US |
Files in this item
This item appears in the following Collection(s)
-
Journal/Magazine Articles
Articles published in local and international journals by the Staff of the Faculty of Medicine