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Chronic renal failure in North Central Province of Sri Lanka: an environmentally induced disease

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dc.contributor.author Wanigasuriya, K. P. en_US
dc.contributor.author Peiris-John, R. J. en_US
dc.contributor.author Wickremasinghe, R. en_US
dc.contributor.author Hittarage, A. en_US
dc.date.accessioned 2014-10-29T09:25:29Z
dc.date.available 2014-10-29T09:25:29Z
dc.date.issued 2007 en_US
dc.identifier.citation Transactions of the Royal Society of Tropical Medicine and Hygiene. 2007; 101(10): pp.1013-17 en_US
dc.identifier.issn 0035-9203 (Print) en_US
dc.identifier.issn 1878-3503 (Electronic) en_US
dc.identifier.uri http://repository.kln.ac.lk/handle/123456789/1816
dc.description Indexed in MEDLINE
dc.description.abstract This study was conducted to determine the aetiology of chronic renal failure (CRF) in the North Central Province of Sri Lanka. Patients (n=183) with CRF of unknown aetiology were compared with controls (n=200) who had no evidence of chronic renal dysfunction. Exposure to possible risk factors were determined by an interviewer-administered questionnaire. Being a farmer (P<0.001), using pesticides (P<0.001), drinking well water (P<0.001), a family history of renal dysfunction (P=0.001), use of ayurvedic treatment (P<0.001) and a history of snake bite (P<0.001) were risk factors for CRF of unknown aetiology. Using logistic regression analysis, a family history of chronic renal disease, taking ayurvedic treatment and history of snake bite were found to be significant predictors for CRF of unknown aetiology. There is evidence to support an environmental aetiology to CRF in Sri Lanka.
dc.publisher Oxford University Press en_US
dc.title Chronic renal failure in North Central Province of Sri Lanka: an environmentally induced disease en_US
dc.type Article en_US
dc.identifier.department Public Health en_US
dc.creator.corporateauthor Royal Society of Tropical Medicine and Hygiene en_US


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