Digital Repository

Changing phenotype of IBD in Sri Lanka

Show simple item record

dc.contributor.author Niriella, M.A. en_US
dc.contributor.author Kodisinghe, S.K. en_US
dc.contributor.author Dinamithra, N.P. en_US
dc.contributor.author Rajapakshe, N. en_US
dc.contributor.author Nanayakkara, S.D. en_US
dc.contributor.author Luke, H.P.D.P. en_US
dc.contributor.author Silva, K.T.M. en_US
dc.contributor.author Dassanayake, A.S. en_US
dc.contributor.author de Silva, A.P. en_US
dc.contributor.author Navarathne, N.M.M. en_US
dc.contributor.author de Silva, H.J. en_US
dc.date.accessioned 2017-10-11T05:33:35Z en_US
dc.date.available 2017-10-11T05:33:35Z en_US
dc.date.issued 2016 en_US
dc.identifier.citation Sri Lanka Medical Association, 129th Anniversary International Medical Congress. 2016: 182 en_US
dc.identifier.issn 0009-0895 en_US
dc.identifier.uri http://repository.kln.ac.lk/handle/123456789/17815 en_US
dc.description Poster Presentation Abstract (PP 55), 129th Anniversary International Medical Congress, Sri Lanka Medical Association, 25-27 July 2016 Colombo, Sri Lanka en_US
dc.description.abstract INTRODUCTION: Inflammatory bowel disease (IBD) is increasing in Asia Pacific, with recent changes in phenotype reported from some countries. METHOD: Patients with histologically proven IBD [ulcerative colitis(UC), Crohn’s disease(CD), unclassified(U)], diagnosed between January 2006-December 2010 (Group 1) and January 2011-December 2015 (Group 2), who had regular follow up, were included from Colombo North Teaching Hospital and National Hospital of Sri Lanka (two main referral centers). The two groups were compared with regard to phenotype of IBD (subgroups, severity, age at diagnosis, duration of symptoms, extra-intestinal manifestations (EIM) at diagnosis, cigarette smoking, family history, and highest therapy during follow up). RESULTS: 304 patients were included [Group 1: UC-72(74.2%), CD-25(25.8%); Group 2: UC-113(54.6%), CD-90(43.5%), U-4(1.9%)]. There were more females in Group 2 for UC and CD. Median age at diagnosis was similar for UC but higher for CD in Group 2 compared to Group 1.The median duration of symptoms to diagnosis was not different for UC and CD in the two groups. In both groups, left sided colitis (E2) predominated for UC and Ileo-colonic disease (L3) and non-stricturing, non-penetrating (B1) disease predominated for CD. There was no difference in degree of severity, rate of complications, pattern of EIM, smoking history at presentation, family history or highest therapy during follow up for either disease in the two groups (Table 1). CONCLUSIONS: During the 10 years, there seems to be a recent increase in the proportion of CD among IBD patients. However, there were no major changes in disease phenotype for UC or CD. en_US
dc.language.iso en_US en_US
dc.publisher Sri Lanka Medical Association en_US
dc.subject Inflammatory Bowel Diseases en_US
dc.title Changing phenotype of IBD in Sri Lanka en_US
dc.type Conference Abstract en_US


Files in this item

Files Size Format View

There are no files associated with this item.

This item appears in the following Collection(s)

  • Conference Papers
    Papers presented at local and international conferences by the Staff of the Faculty of Medicine

Show simple item record

Search Digital Repository


Browse

My Account