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A Comparative study on medical comorbidities among children with autism spectrum disorder and controls in a children’s hospital.

Show simple item record Chandradasa, M. en_US Rohanachandra, Y. en_US Dahanayake, D. en_US Hettiarachchi, D. en_US Gunathilake, M. en_US Fernando, R. en_US Wijetunge, S. en_US 2017-10-03T10:09:23Z en_US 2017-10-03T10:09:23Z en_US 2017 en_US
dc.identifier.citation Sri Lanka Journal of Child Health.2017;46(3):262–266 en_US
dc.identifier.issn 2386-110X en_US
dc.identifier.uri en_US
dc.description Indexed in Scopus, Not in MEDLINE/PUBMED en
dc.description.abstract INTRODUCTION: Autism spectrum disorder (ASD) is a neurodevelopmental disorder, in which medical disorders are known to occur higher than in the general paediatric population. This may indicate either that the neurodevelopmental disorder is acting as a risk factor or sharing a common pathophysiological mechanism with the medical disorder. We could not access any publications focusing on medical comorbidities in autism from Sri Lanka. OBJECTIVE: To compare the prevalence and types of medical comorbidities between children with ASD and outpatient controls presenting to a children’s hospital in Sri Lanka. METHOD: This was an observational analytical study using a case control design. Seventy three consecutive new enrolments diagnosed as ASD at the child psychiatric services of Lady Ridgeway Hospital were recruited to the study group. An age and gender matched group of children presenting to the outpatient department with minor physical problems were recruited as the comparison group. The presence of a medical disorder was determined retrospectively by perusal of medical records. RESULTS: The prevalence of febrile seizures, epilepsy, bronchial asthma, atopic dermatitis and recurrent gastrointestinal symptoms in the child were higher in the ASD group compared to the control group. The differences of the rates between groups for bronchial asthma and recurrent gastrointestinal symptoms were statistically significant. Also, pregnancy induced hypertension and gestational diabetes mellitus in the mother was higher in ASD group. CONCLUSIONS: The probability of co-occurrence of certain medical disorders is significantly higher in children with ASD (neurological, respiratory, gastrointestinal and dermatological disorders) in comparison to controls. en_US
dc.language.iso en_US en_US
dc.publisher Sri Lanka College of Paediatricians en_US
dc.subject Autism Spectrum Disorder en_US
dc.subject.mesh Neurodevelopmental Disorders en_US
dc.subject.mesh Child en_US
dc.subject.mesh Comorbidity
dc.title A Comparative study on medical comorbidities among children with autism spectrum disorder and controls in a children’s hospital. en_US
dc.type Article en_US

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