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The Effect of acyclovir on the acute and latent murine gammaherpesvirus-68 infection of mice
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| dc.contributor.author | Sunil-Chandra, N.P. | |
| dc.contributor.author | Efstathiou, S. | |
| dc.contributor.author | Nash, A.A. | |
| dc.date.accessioned | 2017-09-14T14:27:50Z | |
| dc.date.available | 2017-09-14T14:27:50Z | |
| dc.date.issued | 1994 | |
| dc.identifier.citation | Antiviral Chemistry and Chemotherapy. 1994; 5(6): 290-296 | en_US |
| dc.identifier.issn | 0956-3202 (Print) | |
| dc.identifier.issn | 2040-2066 (Electronic) | |
| dc.identifier.issn | 0956-3202 (Linking) | |
| dc.identifier.other | 10.1177/095632029400500502 | en |
| dc.identifier.uri | http://repository.kln.ac.lk/handle/123456789/17469 | |
| dc.description.abstract | Mice inoculated intranasally with murine gammaherpesvirus-68 were used to evaluate the efficacy of acyclovir (ACV) in the treatment of acute and latent infections. Effectiveness was measured by infectious virus assay of the lung (site of active replication) and infectious centre assay of spleen cells (site of latency). Intraperitoneal administration of ACV at 6-h intervals starting soon after inoculation was more effective in reducing infectious virus in the lung than was treatment with 12-hourly injections commencing 3 days post-infection. | en_US |
| dc.language.iso | en_US | en_US |
| dc.publisher | Sage Publishing | en_US |
| dc.relation.uri | http://journals.sagepub.com/doi/abs/10.1177/095632029400500502 | en |
| dc.subject.mesh | Gammaherpesvirinae | |
| dc.subject.mesh | Gammaherpesvirinae-pathogenicity | |
| dc.subject.mesh | Gammaherpesvirinae-physiology | |
| dc.subject.mesh | Gammaherpesvirinae-drug effects | |
| dc.subject.mesh | Herpesviridae Infections-virology | |
| dc.subject.mesh | Herpesviridae Infections | |
| dc.subject.mesh | Herpesviridae-drug effects | |
| dc.subject.mesh | Herpesviridae-pathogenicity | |
| dc.subject.mesh | Virus Latency | |
| dc.title | The Effect of acyclovir on the acute and latent murine gammaherpesvirus-68 infection of mice | en_US |
| dc.type | Article | en_US |
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Journal/Magazine Articles
Articles published in local and international journals by the Staff of the Faculty of Medicine