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Short and medium term glycaemic control after pancreaticoduodenectomy

Show simple item record Siriwardana, R.C. en Bandara, L.M.P.M. en Atulugama, N. en Gunetilleke, M.B. en_US Ekanayake, C.S. en 2017-02-01T06:19:09Z en 2017-02-01T06:19:09Z en 2016 en_US
dc.identifier.citation Sri Lanka Journal of Surgery. 2016; 34(4): 11–15 en_US
dc.identifier.issn 2279-2201 en_US
dc.identifier.uri en_US
dc.description.abstract Introduction: Perioperative outcomes of pancreaticoduodenectomy (PD) have improved over the years. Glycaemic control in longterm survivors is a matter of concern. Materials and methods: 48 surviving patients of 66 patients who underwent Whipple surgery from 2011 to 2015 were evaluated. Patients with recurrences, who had chemotherapy within three months and patients who had not completed a minimum six months follow-up were excluded. 25 patients were selected. Patients' demographic data, HbA1c level, fasting blood sugar level, physical activity index and waist to hip ratio were calculated. Volume of the pancreatic specimen was calculated. Non diabetics underwent oral glucose tolerance test (OGTT). Results: There were 6 (24%) pre-existing diabetics, 3 new onset diabetics and two patients with impaired glucose tolerance (20%). Median preoperative BMI, body fat distribution, calculated median pancreatic volumes resected or underlying pancreatic pathology did not differ in diabetic and non-diabetic groups. In non-diabetics, HbA1c level or two hour OGTT did not associate with age, preoperative BMI, waist to hip ratio and resected pancreatic volumes. Conclusion: Significant proportion of patients develop diabetes immediately after PD. Reliable prediction of this group pre-operatively is difficult due to many interacting, confounding factors. They need close monitoring in immediate perioperative period. en_US
dc.language.iso en_US en_US
dc.publisher College of Surgeons of Sri Lanka en_US
dc.subject glycaemic control en_US
dc.title Short and medium term glycaemic control after pancreaticoduodenectomy en_US
dc.type Article en_US

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