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Yellow oleander poisoning in Sri Lanka: outcome in a secondary care hospital

Show simple item record Fonseka, M.M.D. en_US Seneviratne, S.L. en_US de Silva, C.E. en_US Gunatilake, S.B. en_US de Silva, H.J. en_US 2014-10-29T09:19:32Z 2014-10-29T09:19:32Z 2002 en_US
dc.identifier.citation Human and Experimental Toxicology. 2002; 21(6): pp.293-295 en_US
dc.identifier.issn 0960-3271 (Print) en_US
dc.identifier.issn 1477-0903 (Electronic) en_US
dc.description Indexed in MEDLINE
dc.description.abstract Cardiac toxicity after self-poisoning from ingestion of yellow oleander seeds is common in Sri Lanka. We studied all patients with yellow oleanderpoisoning (YOP) admitted to a secondary care hospital in north central Sri Lanka from May to August 1999, with the objective of determining theoutcome of management using currently available treatment. Patients with bradyarrhythmias were treated with intravenous boluses of atropine and intravenous infusions of isoprenaline. Temporary cardiac pacing was done for those not responding to drug therapy. During the study period 168 patients with YOP were admitted to the hospital (male:female = 55:113). There were six deaths (2.4%), four had third-degree heart block and two died of undetermined causes. They died soon after delayed admission to the hospital before any definitive treatment could be instituted. Of the remaining 162 patients, 90 (55.6%) patients required treatment, and 80 were treated with only atropine and/or isoprenaline while 10 required cardiac pacing in addition. Twenty-five (14.8%) patients had arrhythmias that were considered life threatening (second-degree heart block type II, third-degree heart block and nodal bradycardia). All patients who were treated made a complete recovery. Only a small proportion of patients (17%) admitted with YOP developed life-threatening cardiac arrhythmias. Treatment with atropine and isoprenaline was safe and adequate in most cases en_US
dc.publisher SAGE Publishing en_US
dc.subject Poisoning en_US
dc.subject Heart Block-chemically induced en_US
dc.subject Thevetia-poisoning en_US
dc.subject Cause of Death en_US
dc.subject Retrospective Studies en_US
dc.title Yellow oleander poisoning in Sri Lanka: outcome in a secondary care hospital en_US
dc.type Article en_US
dc.identifier.department Medicine en_US
dc.creator.corporateauthor British Toxicology Society en_US

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