Browsing Journal/Magazine Articles by Author "Premawansa, S."

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Changes in full blood count parameters in leptospirosis: a prospective study

de Silva, N.L.; Niloofa, M.; Fernando, N.; Karunanayake, L.; Rodrigo, C.; de Silva, H.J.; Premawansa, S.; Handunnetti, S.M.; Rajapakse, S. (BioMed Central, 2014)

BACKGROUND: Leptospirosis presents diagnostic challenges to clinicians, in settings where other acute febrile illness are prevalent. The patterns of serial changes in haematological parameters in leptospirosis has not been ...
Development of an in-house ELISA as an alternative method for the serodiagnosis of leptospirosis

Niloofa, R.; Karunanayake, L.; de Silva, H.J.; Premawansa, S.; Rajapakse, S.; Handunnetti, S. (Elsevier, 2021)

BACKGROUND: Leptospirosis is most often clinically diagnosed and a laboratory test with high diagnostic accuracies is required. METHODOLOGY: IgM and IgG-ELISAs using Leptospira antigens were established and evaluated in ...
Diagnosis of leptospirosis: comparison between microscopic agglutination test, IgM-ELISA and IgM rapid immunochromatography test

Niloofa, R.; Fernando, N.; de Silva, N.L.; Karunanayake, L.; Wickramasinghe, H.; Dikmadugoda, N.; Premawansa, G.; Wickremasinghe, A.R.; de Silva, H.J.; Premawansa, S.; Rajapakse, S.; Handunnetti, S. (Public Library of Science, 2015)

BACKGROUND: Leptospirosis is diagnosed on clinical grounds, and confirmed by microscopic agglutination test (MAT). IgM-ELISA (Serion-Virion) and immunochromatography test (Leptocheck-WB) are two immunodiagnostic assays ...
A Diagnostic scoring model for Leptospirosis in resource limited settings

Rajapakse, S.; Weeratunga, P.; Niloofa, R.; Fernando, N.; de Silva, N.L.; Rodrigo, C.; Maduranga, S.; Nandasiri, N.; Premawansa, S.; Karunanayake, L.; de Silva, H.J.; Handunnetti, S. (Public Library of Science, 2016)

Leptospirosis is a zoonotic infection with significant morbidity and mortality. The clinical presentation of leptospirosis is known to mimic the clinical profile of other prevalent tropical fevers. Laboratory confirmation ...
Effect of antimicrobial agents on inflammatory cytokines in acute Leptospirosis

Fernando, N.; de Silva, R.; Hadunnetti, S.M.; Karunanayake, L.; de Silva, N.L.; de Silva, H.J.; Rajapakse, S.; Premawansa, S. (American Society for Microbiology, 2018)

The aim of this study was to assess the inflammatory cytokine response and possible association with antimicrobial treatment with penicillin, ceftriaxone, and doxycycline in acute leptospirosis. In the early acute stage, ...
High levels of serum angiopoietin 2 and angiopoietin 2/1 ratio at the critical stage of Dengue Hemorrhagic Fever in patients and association with clinical and biochemical parameters

Mapalagamage, M.; Handunnetti, S.M.; Wickremasinghe, A.R.; Premawansa, G.; Thillainathan, S.; Fernando, T.; Kanapathippillai, K.; de Silva, A.D.; Premawansa, S. (American Society for Microbiology., 2020)

ABSTRACT:Longitudinal changes of serum angiopoietin 1 (Ang-1) and angiopoietin 2 (Ang-2) associated with endothelial stability in dengue patients with different disease stages were studied. Serum Ang-1 and Ang-2 levels ...
Is Total Serum Nitrite and Nitrate (NOx) Level in Dengue Patients a Potential Prognostic Marker of Dengue Hemorrhagic Fever?

Mapalagamage, M.; Handunnetti, S.; Premawansa, G.; Thillainathan, S.; Fernando, T.; Kanapathippillai, K.; Wickremasinghe, R.; de Silva, A.D.; Premawansa, S. (Hindawi Pub. Corp., 2018)

Potential use of total nitrite plus nitrate (NOx) and nitrite (NO2-) separately as surrogate markers for serum nitric oxide in severe dengue and their longitudinal changes along with the progression of infection was studied. ...
Leptospirosis: challenges in diagnosis, and predictors of severity

Rajapakse, S.; Fernando, N.; Niloofa, M.J.R.; de Silva, H.J.; Karunanayake, L.; Premawansa, S.; Handunnetti, S.M. (Ceylon College of Physicians, 2016)

No Abstract available
The ParaSightT-F dipstick test as a routine diagnostic tool for malaria in Sri Lanka

Kodisinghe, H.M.; Perera, K.L.R.L.; Premawansa, S.; Naotunne, T. de S.; Wickremasinghe, A.R.; Mendis, K.N. (Oxford University Press, 1997)

Blood from 1053 persons who presented for treatment at outpatient clinics of government health institutions in Sri Lanka, and 250 who took part in a blood survey for malaria, was examined by thick blood film microscopy ...
Predictive value of hepatic transaminases during febrile phase as a predictor of a severe form of dengue: analysis of adult dengue patients from a tertiary care setting of Sri Lanka

Priyangika, D.K.D.; Premawansa, G.; Adikari, M.; Thillainathan, S.; Premawansa, S.; Jayamanne, B.D.W.; Premaratna, R. (Biomed Central, 2021)

OBJECTIVES: Dengue viral infection is an ongoing epidemic in Sri Lanka, causing significant mortality and morbidity. A descriptive-analytical study was carried out using serologically confirmed Dengue patients during a ...
Protein Carbonyl as a biomarker of oxidative stress in severe Leptospirosis, and its usefulness in differentiating Leptospirosis from Dengue Infections

Fernando, N.; Wickremesinghe, S.; Niloofa, R.; Rodrigo, C.; Karunanayake, L.; de Silva, H.J.; Wickremasinghe, A.R.; Premawansa, S.; Rajapakse, S.; Handunnetti, S.M. (Public Library of Science, 2016)

Pathogenesis of disease severity in leptospirosis is not clearly understood whether it is due to direct damage by pathogen or by adverse immune responses. Knowledge on biomarkers of oxidative stress which could be used in ...

Browsing Journal/Magazine Articles by Author "Premawansa, S."

Browsing Journal/Magazine Articles by Author "Premawansa, S."

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