Hapuarachchi, H.A.C.; Dayanath, M.Y.D.; Bandara, K.B.A.T.; Abeysundara, S.; Abeyewickreme, W.; de Silva, N.R.; Hunt, S.Y.; Sibley, C.H.
(American Society of Tropical Medicine and Hygiene, 2006)
Sulfadoxine-pyrimethamine (SP) is the second-line treatment for Plasmodium falciparum malaria in Sri Lanka. Resistance to SP is caused by point mutations in the dihydrofolate reductase (Pf-dhfr) and dihydropteroate synthase ...