Browsing Journal/Magazine Articles by Author "Chackrewarthy, S."

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Chemical modifications monitored by electrospray mass-spectrometry: A rapid and simple method for identifying and studying functional residues in protiens and enzymes

Krell, T.; Chackrewarthy, S.; Pitt, A.R.; Elwell, A.; Coggins, J.R. (Munksgaard, 1998)

A simple method to identify functional amino acids in enzymes is described. This method is based on the mass spectrometric detection of molecular weight changes as the consequence of chemical modification of enzymes with ...
Common variants at the GCK, GCKR, G6PC2-ABCB11 andMTNR1B loci are associated with fasting glucose in two Asian populations

Takeuchi, F.; Katsuya, T.; Chackrewarthy, S.; Yamamoto, K.; Fujioka, A.; Serizawa, M.; Fujisawa, T.; Nakashima, E.; Ohnaka, K.; Ikegami, H.; Sugiyama, T.; Nabika, T.; Kasturiratne, A.; Yamaguchi, S.; Kono, S.; Takayanagi, R.; Yamori, Y.; Kobayashi, S.; Ogihara, T.; de Silva, A.; Wickremasinghe, R.; Kato, N. (Springer-Verlag, 2010)
A Comparison between revised NCEP ATP III and IDF definitions in diagnosing metabolic syndrome in an urban Sri Lankan population: the Ragama Health Study

Chackrewarthy, S.; Gunasekara, D.; Pathmeswaran, A.; Wijekoon, C.N.; Ranawaka, U.K.; Kato, N.; Takeuchi, F.; Wickremasinghe, A.R. (Hindawi Publishing Corporation, 2013)

Background. The prevalence of metabolic syndrome (MetS) within individual cohorts varies with the definition used. The aim of this study was to compare the prevalence of MetS between IDF and revised NCEP ATP III criteria ...
Crystallization and preliminary x-ray analysis of shikimate dehydrogenase from Escherichia coli

Maclean, J.; Campbell, S.J.; Pollock, K.; Chackrewarthy, S.; Coggins, J.R.; Lapthorn, A.J. (Wiley-Blackwell, 2000)

Abstract
The Effect of Cassia auriculata and Cardiospermum halicacabum teas on the steady state blood level and toxicity of carbamazepine

Thabrew, M.I.; Munasinghe, C.; Chackrewarthy, S.; Senarath, S. (Elsevier, 2004)

A study was conducted using male Wistar rats as the experimental model, to compare the effects of concurrent administration of herbal tea prepared from dried flowers of Cassia auriculata or aerial parts of Cardiospermum ...
Erythrocyte antioxidant enzymes in patients with cataract

Chandrasena, L.G.; Chackrewarthy, S.; Perera, P.T.; de Silva, D. (Institute for Clinical Science., 2006)

The pathogenesis of cataract has been found to be influenced by a number of factors including oxidative stress. Catalase, glutathione peroxidase (GPX), and superoxide dismutase (SOD) are some of the antioxidant enzymes ...
Evaluation of the hypoglycemic and hypolipidemic effects of an ethylacetate fraction of Artocarpus heterophyllus (jak) leaves in streptozotocin-induced diabetic rats

Chackrewarthy, S.; Thabrew, M.I.; Weerasuriya, M.K.; Jayasekera, S. (Medknow Publications, 2010)

Aqueous extracts of mature leaves of Artocarpus heterophyllus (jak) are used by traditional medical practitioners in Sri Lanka and India for the treatment of diabetes. This study was conducted to investigate the hypoglycemic ...
Micronutrient status and its relationship with nutritional status in preschool children in urban Sri Lanka

Marasinghe, E.; Chackrewarthy, S.; Abeysena, C.; Rajindrajith, S. (HEC Press, Australia, 2015)

OBJECTIVE: To assess the micronutrient status and its relationship with nutritional status in preschool children. METHODS: In a cross sectional study, anthropometric data and fasting blood samples were obtained from 340 ...
Patterns and predictors of mortality in a semi-urban population-based cohort in Sri Lanka: findings from the Ragama Health Study

Kasturiratne, A.; Ediriweera, D.S.; de Silva, S.T.; Niriella, M.A.; Thulani, U.B.; Pathmeswaran, A.; Dassanayake, A.S.; de Silva, A.P.; Chackrewarthy, S.; Ranawaka, U.; Kato, N.; Wickremasinghe, A.R.; de Silva, H.J. (BMJ Publishing Group Ltd, 2020)

OBJECTIVE: To describe patterns and predictors of mortality in a semi-urban population in Sri Lanka. DESIGN: A prospective population-based cohort study. Setting: Ragama Medical Officer of Health area in the Gampaha district, ...
Physical activity tracking among Sri Lankan adults: findings from a 7-year follow-up of the Ragama Health Study

Pinidiyapathirage, J.; Kasturiratne, A.; Bennie, J.A.; Pathmeswaran, A.; Biddle, S.J.H.; de Silva, H.J.; Chackrewarthy, S.; Dassanayake, A.S.; Ranawaka, U.; Kato, N.; Wickremasinghe, A.R. (SAGE Publications, 2021)

ABSTRACT: Limited data are available on physical activity tracking among adults in low- and middle-income countries. Using a longitudinal design, we assessed trends and correlates of physical activity among Sri Lankan ...
Possible interaction of herbal tea and carbamazepine

Thabrew, M.I.; Munasinghe, T.M.J.; Chackrewarthy, S.; Senarath, S. (De Gruyter, 2003)

A study was conducted using Wistar rats to determine the effect of concurrent administration of a herbal tea prepared from dried flowers of Cassia auriculata and carbamazepine on (a) blood levels of the prescription drug ...
Prevalence and risk factors for non-alcoholic fatty liver disease among adults in an urban Sri Lankan population

Dassanayake, A.S.; Kasturiratne, A.; Rajindrajith, S.; Kalubowila, U.; Chackrewarthy, S.; de Silva, A.P.; Makaya, M.; Mizoue, T.; Kato, N.; Wickremasinghe, A.R.; de Silva, H.J. (Wiley-Blackwell, 2009)

BACKGROUND AND AIMS: Non-alcoholic fatty liver disease (NAFLD) is an emerging problem in the Asia-Pacific region. However, its prevalence and risk factors in Asian (especially South Asian) communities is poorly studied. ...
Risk estimates of cardiovascular diseases in a Sri Lankan community

Ranawaka, U.K.; Wijekoon, C.N.; Pathmeswaran, A.; Kasturiratne, A.; Gunasekara, D.; Chackrewarthy, S.; Kato, N.; Wickremasinghe, A.R. (Sri Lanka Medical Association, 2016)

OBJECTIVES: Quantifying the risk of cardiovascular disease (CVD) in a community is important in planning preventive strategies, but such data are limited from developing countries, especially South Asia. We aimed to estimate ...
Systematic fine-mapping of association with BMI and type 2 diabetes at the FTO locus by integrating results from multiple ethnic groups

Akiyama, K.; Takeuchi, F.; Isono, M.; Chackrewarthy, S.; Nguyen, Q.N.; Wen, W.; Yamamoto, K.; Katsuya, T.; Kasturiratne, A.; Pham, S.T.; Zheng, W.; Matsushita, Y.; Kishimoto, M.; Do, L.D.; Shu, X.O.; Wickremasinghe, A.R.; Kajio, H.; Kato, N. (Public Library of Science, 2014)

BACKGROUND/OBJECTIVE: The 16q12.2 locus in the first intron of FTO has been robustly associated with body mass index (BMI) and type 2 diabetes in genome-wide association studies (GWAS). To improve the resolution of fine-scale ...
Utility of glycosylated haemoglobin in diagnosing diabetes in an urban Sri Lankan community

Wijekoon, C.N.; Pathmeswaran, A.; Chackrewarthy, S.; Kato, N.; Wickremasinghe, A.R. (Sri Lanka Medical Association, 2017)

INTRODUCTION: American Diabetes Association (ADA) has officially endorsed glycosylated haemoglobin (HbA1c) as a diagnostic tool. The recommended cut-off for diagnosing diabetes is  6.5%. OBJECTIVES: To compare use of HbA1c ...

Browsing Journal/Magazine Articles by Author "Chackrewarthy, S."

Browsing Journal/Magazine Articles by Author "Chackrewarthy, S."

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