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Browsing Journal/Magazine Articles by Author "Lalloo, D.G."

Browsing Journal/Magazine Articles by Author "Lalloo, D.G."

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  • Multiple-dose activated charcoal in yellow oleander poisoning 
    de Silva, H.A.; Pathmeswaran, A.; Lalloo, D.G.; de Silva, H.J.; Aronson, J.K. (Lancet Publishing Group, 2008)
    Comment on : Michael Eddleston and colleagues (Lancet. 2008 Feb 16;371(9612):579-87)study. No Abstract Available
  • Neurophysiological findings in patients 1 year after snake bite induced neurotoxicity in Sri Lanka 
    Bell, D.J.; Wijegunasinghe, D.; Samarakoon, S.; Palipana, H.; Gunasekera, S.; de Silva, H.A.; Lalloo, D.G.; Ranawaka, U.K.; de Silva, H.J. (Oxford University Press, 2010)
    Snake bite causes significant morbidity and mortality in Sri Lanka. Snake venoms contain neurotoxins that block neuromuscular junction transmission. Presynaptic neurotoxicity most commonly causes destruction of nerve ...
  • Neurotoxicity in snakebite--the limits of our knowledge 
    Ranawaka, U.K.; Lalloo, D.G.; de Silva, H.J. (Public Library of Science, 2013)
    Snakebite is classified by the WHO as a neglected tropical disease. Envenoming is a significant public health problem in tropical and subtropical regions. Neurotoxicity is a key feature of some envenomings, and there are ...
  • Poor diagnostic accuracy of commercial antibody-based assays for the diagnosis of acute Chikungunya infection 
    Blacksell, S.D.; Tanganuchitcharnchai, A.; Jarman, R.G.; Gibbons, R.V.; Paris, D.H.; Bailey, M.S.; Day, N.P.; Premaratna, R.; Lalloo, D.G.; de Silva, H.J. (American Society for Microbiology, 2011)
    A Sri Lankan fever cohort (n = 292 patients; 17.8% prevalence) was used to assess two standard diagnostic Chikungunya IgM tests. The immunochromatographic test (ICT) acute sample sensitivity (SN) was 1.9 to 3.9%, and ...
  • Population pharmacokinetics of an Indian F(ab')2 snake antivenom in patients with Russell's Viper (Daboia russelii) bites 
    Isbister, G.K.; Maduwage, K.; Saiao, A.; Buckley, N.A.; Jayamanne, S.F.; Seyed, S.; Mohamed, F.; Chathuranga, U.; Mendes, A.; Abeysinghe, C.; Karunathilake, H.; Gawarammana, I.; Lalloo, D.G.; de Silva, H.J. (Public Library of Science, 2015)
    BACKGROUND: There is limited information on antivenom pharmacokinetics. This study aimed to investigate the pharmacokinetics of an Indian snake antivenom in humans with Russell's viper bites. METHODS/PRINCIPAL FINDINGS: ...
  • A Randomized Controlled Trial of a brief Intervention for delayed psychological effects in snakebite victims 
    Wijesinghe, C.A.; Williams, S.S.; Kasturiratne, A.; Dolawaththa, N.; Wimalaratne, P.; Wijewickrema, B.; Jayamanne, S.F.; Isbister, G.K.; Dawson, A.H.; Lalloo, D.G.; de Silva, H.J. (Public Library of Science, 2015)
    BACKGROUND: Snakebite results in delayed psychological morbidity and negative psycho-social impact. However, psychological support is rarely provided to victims. AIM: To assess the effectiveness of a brief intervention ...
  • A Randomized controlled trial of fresh frozen plasma for coagulopathy in Russell's viper (Daboia russelii) envenoming 
    Isbister, G.K.; Jayamanne, S.; Mohamed, F.; Dawson, A.H.; Maduwage, K.; Gawarammana, I.; Lalloo, D.G.; de Silva, H.J.; Scorgie, F.E.; Lincz, L.F.; Buckley, N.A. (Wiley-Blackwell, 2017)
    BACKGROUND: Russell's viper (Daboia russelii) envenoming is a major health issue in South Asia and causes venom induced consumption coagulopathy (VICC). OBJECTIVES: We investigated the effect of fresh frozen plasma (FFP) ...
  • Snake antivenom for snake venom induced consumption coagulopathy 
    Maduwage, K.; Buckley, N.A.; de Silva, H.J.; Lalloo, D.G.; Isbister, G.K. (Update Software, 2015)
    BACKGROUND : Snake venom induced consumption coagulopathy is a major systemic effect of envenoming. Observational studies suggest that antivenom improves outcomes for venom induced consumption coagulopathy in some snakebites ...
  • Snakebite: the true disease burden has yet to be determined 
    de Silva, H.J.; Kasturiratne, A.; Pathmeswaran, A.; Lalloo, D.G. (Sri Lanka Medical Association, 2013)
    Venomous snakes are a significant cause of morbidity and mortality, particularly in tropical and subtropical countries in Africa, Asia, Oceania and Latin America. Most snake bites occur in the rural tropics, and result in ...
  • The Socio-economic burden of snakebite in Sri Lanka 
    Kasturiratne, A.; Pathmeswaran, A.; Wickremasinghe, A.R.; Jayamanne, S.F.; Dawson, A.; Isbister, G.K.; de Silva, H.J.; Lalloo, D.G. (Public Library of Science, 2017)
    BACKGROUND: Snakebite is a major problem affecting the rural poor in many of the poorest countries in the tropics. However, the scale of the socio-economic burden has rarely been studied. We undertook a comprehensive ...
  • Underestimation of snakebite mortality by hospital statistics in the Monaragala District of Sri Lanka 
    Fox, S.; Rathuwithana, A.C.; Kasturiratne, A.; Lalloo, D.G.; de Silva, H.J. (Oxford University Press, 2006)
    Estimates of snakebite mortality are mostly based on hospital data, although these may considerably underestimate the problem. In order to determine the accuracy of hospital-based statistics, data on snakebite mortality ...

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