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Levamisole induced toxic epidermal necrolysis in a patient with nephrotic syndrome: A case report

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dc.contributor.author Prasangika, T.G.C.
dc.contributor.author Warnasuriya, W.
dc.contributor.author Mendis, W.J.S.
dc.contributor.author Fernando, M.
dc.contributor.author Jayasinghe, C.
dc.date.accessioned 2016-04-28T05:56:39Z
dc.date.available 2016-04-28T05:56:39Z
dc.date.issued 2016
dc.identifier.citation Proceedings of the 25th Anniversary International Scientific Conference. Faculty of Medicine, University of Kelaniya; 2016: 84 en_US
dc.identifier.uri http://repository.kln.ac.lk/handle/123456789/12831
dc.description Free paper session 1: Non Communicable Diseases OP 3 - 25th Anniversary International Scientific Conference, 6-8 April 2016, Faculty of Medicine,University of Kelaniya, Sri Lanka en_US
dc.description.abstract INTRODUCTION: Toxic epidermal necrolysis (TEN) is an uncommon, potentially life-threatening muco-cutaneous condition, which may occur as an adverse reaction (Type IV hypersensitivity) to a number of drugs. It is characterized by variable degrees of epidermal necrosis and detachment leading to increase morbidity and mortality. We describe the case of a patient with nephrotic syndrome who developed TEN, presumably induced by Levamisole. To our knowledge, this is the first report of TEN arising during levamisole treatment. CASE REPORT: A 11 year old girl, who has steroid dependent nephrotic syndrome, was started on levamisole. She developed skin and mucosal lesions suggestive of TEN 3 weeks after taking levamisole. The diagnosis of TEN in our patient was made clinically and confirmed histologically. Based on the temporal relationship of levamisole therapy and the development of her adverse cutaneous reaction, we concluded that levamisole was the offending agent. CONCLUSION: We report this case to increase awareness of this potential life-threatening complication of levamisole. en_US
dc.language.iso en_US en_US
dc.publisher Faculty of Medicine, University of Kelaniya, Sri Lanka en_US
dc.subject toxic en_US
dc.title Levamisole induced toxic epidermal necrolysis in a patient with nephrotic syndrome: A case report en_US
dc.type Article en_US


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