dc.contributor.author |
Selliah, S. |
en_US |
dc.contributor.author |
de Mel, T. |
en_US |
dc.contributor.author |
Hewamadduma, C.A.A. |
en_US |
dc.contributor.author |
de Tissera, A. |
en_US |
dc.date.accessioned |
2014-10-29T09:14:33Z |
|
dc.date.available |
2014-10-29T09:14:33Z |
|
dc.date.issued |
1995 |
en_US |
dc.identifier.citation |
The Ceylon Medical Journal. 1995; 40(2): pp.97-100 |
en_US |
dc.identifier.issn |
0009-0875 (Print) |
en_US |
dc.identifier.uri |
http://repository.kln.ac.lk/handle/123456789/1252 |
|
dc.description |
Indexed in MEDLINE |
|
dc.description.abstract |
OBJECTIVE:To determine whether inclusion of vitamin E into kidney storage solutions protects metabolism and tubular ultrastructure of stored rat kidney. METHODS: Rat kidneys were flush stored in Marshall's Citrate (MC) and MC + vitamin E (25% of LD 50 and 50% of LD 50) for 24 hours at 0 degrees C. After storage kidney slices were tested for gluconeogenesis and lactate dehydrogenase (LDH) activity, and examined for cellular ultrastructure. RESULTS: Kidneys stored in MC + vitamin E gave higher gluconeogenesis than those stored in MC alone (p < 0.001). Tubular ultrastructure was better preserved in the presence of Vitamin E. CONCLUSIONS: Vitamin E appears to protect the metabolism and ultrastructure of stored rat kidneys. |
|
dc.publisher |
Sri Lanka Medical Association |
en_US |
dc.subject |
Gluconeogenesis-drug effects |
|
dc.subject |
Kidney-metabolism |
|
dc.subject |
Organ Preservation |
|
dc.subject |
Vitamin E-pharmacology |
|
dc.title |
Protective effect of vitamin E in kidney storage solution on renal tissue metabolism in rats |
en_US |
dc.type |
Article |
en_US |
dc.identifier.department |
Physiology |
en_US |
dc.creator.corporateauthor |
Sri Lanka Medical Association |
en_US |