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Clostridium difficile infection in inflammatory bowel disease patients in Sri Lanka

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dc.contributor.author Waraketiya, P.R.
dc.contributor.author de Silva, A.P.
dc.contributor.author Wijesinghe, N.T.
dc.contributor.author Waraketiya, P.R.
dc.contributor.author Wijewantha, H.S.
dc.contributor.author Chandrasena, L.G.
dc.contributor.author Pathmeswaran, A.
dc.contributor.author de Silva, H.J.
dc.date.accessioned 2016-04-01T08:23:08Z
dc.date.available 2016-04-01T08:23:08Z
dc.date.issued 2012
dc.identifier.citation Sri Lanka Medical Association, 125th International Medical Congress. 2012;57 Suppliment1: 150 en_US
dc.identifier.issn 0009-0895
dc.identifier.uri http://repository.kln.ac.lk/handle/123456789/12427
dc.description Poster Presentation Abstract (PP 163), 125th Anniversary Scientific Medical Congress, Sri Lanka Medical Association, June 2012 Colombo, Sri Lanka en_US
dc.description.abstract INTRODUCTION: Over the last decade an increase in Clostridium difficile associated diarrhoea (CDAD) has been observed among Caucasians (1%). The frequency of CDAD is very high in Caucasian IBD patients; 8.7% in one study of IBD patients in remission. This has led to guidelines recommending routine screening for CDAD in IBD. Clinical impressions are that CDAD is rare among Sri Lankans. AIMS: This study was conducted to determine the frequency of CDAD in a cohort of Sri Lankan IBD patients and healthy controls. METHODS: Cases [n=154] were histologically confirmed IBD patients, in clinical remission. The controls [n=100) were non-IBD patients who presented to medical clinics without diarrhoea and with no exposure to antibiotics for up to 8 weeks prior to recruitment. Immunoassays for Clostridium difficile toxins A and B were performed on stool samples obtained from both groups. RESULTS: The frequency of CDAD was 0.7% (n=l) and 0% (n=0) in IBD patients and controls respectively. CONCLUSIONS: Compared to Caucasians, CDAD was very rare in this cohort of Sri Lankans, including those with IBD. Routine screening for CDAD does not seem necessary in our setting. en_US
dc.language.iso en_US en_US
dc.publisher Sri Lanka Medical Association en_US
dc.subject Clostridium difficile infection en_US
dc.title Clostridium difficile infection in inflammatory bowel disease patients in Sri Lanka en_US
dc.type Article en_US


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