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Evaluation of the efficacy of Melothria maderaspatana in the alleviation of carbon tetrachloride-induced liver dysfunction

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dc.contributor.author Thabrew, M.I. en_US
dc.contributor.author Jayathilake, K.A. en_US
dc.contributor.author Perera, D.J. en_US
dc.date.accessioned 2014-10-29T09:09:58Z
dc.date.available 2014-10-29T09:09:58Z
dc.date.issued 1988 en_US
dc.identifier.citation Journal of Ethnopharmacology. 1988; 23(2-3): pp.305-312 en_US
dc.identifier.issn 0378-8741 (Print) en_US
dc.identifier.issn 1872-7573 (Electronic) en_US
dc.identifier.uri http://repository.kln.ac.lk/handle/123456789/1116
dc.description Indexed in MEDLINE
dc.description.abstract An investigation was carried out to evaluate the ability of Melothria maderaspatana to protect the livers of albino rats from carbon tetrachloride-mediated alterations in liver histopathology and serum levels of alanine aminotransferase, aspartate aminotransferase and alkaline phosphatase. Treatment with an aqueous extract of Melothria aerial parts (either before or after CCl4 administration) markedly decreased CCl4-mediated alterations in liver histopathology as well as serum enzyme levels. Results provide supportive evidence for the folklore view that this plant is a good hepatotonic
dc.publisher Elsevier en_US
dc.subject Carbon Tetrachloride Poisoning
dc.subject Carbon Tetrachloride Poisoning-drug therapy
dc.subject Drug-Induced Liver Injury
dc.subject Drug-Induced Liver Injury-drug therapy
dc.subject Plant Extracts
dc.subject Plant Extracts-therapeutic use
dc.title Evaluation of the efficacy of Melothria maderaspatana in the alleviation of carbon tetrachloride-induced liver dysfunction en_US
dc.type Article en_US
dc.identifier.department Biochemistry en_US
dc.creator.corporateauthor International Society for Ethnopharmacology en_US


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