Wickramarachchi Ayurveda Institute-Gampaha
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Item Agronomic evaluation of brinjal (Solanum melongena L.) and groundnut (Arachis hypogaea L.) intercropping system(Gampaha Wickramarachchi Ayurveda Institute, 2009) Prashaanth, R.; Seran, T.H.; Brintha, I.; Sivachandiran, S.Item Analgesic Activity of Water Extract of Spilanthes acmella Flowers on Rats(Journal of Trop medical plants, 2001) Peiris, K.P.P.; Silva, G.K.J.; Ratnasooriya, W.D.The objective of this study was to evaluate the analgesic potential of fresh flowers of Spilanthes acmella Murr. (family: Compositae) used by some Sri Lankan traditional medical practitioners to suppress toothache. Different doses of water extract of fresh flowers (111,335 and 671 mg kg-1 ) were orally administered to male rats and their analgesic potential was determined at different post treatment periods by using hot plate and tail flick tests. Sedative potential of the extract was evaluated by using rat hole board technique. The extract was well tolerated. A dose-dependent analgesic activity with a EC50 =313 mg kg-1was evident when evaluated in hot plate but not in tail flick test. This analgesic activity had a rapid onset and short duration of action and was not blocked by naloxone, an opioid receptor antagonist. The mid dose of the also induced significant sedation, It is concluded that the analgesic activity is mediated supra-spinally accompanied with sedation.Item Analysis of Rakthamokshana Treatment in Ayurveda Medical Practice in Sri Lanka(Project Report, Graduate Studies Division, Gampaha Wickramarachchi Ayurveda Institute, University of Kelaniya, Sri Lanka., 2017) Adihetti, C.M.; Dissanayake, K.G.C.Panchakarma treatments has very special place in Ayurvedic medicine & they use in whole Ashtanga Ayurveda. Vamana (emetic theraphy), virechana (purgation theraphy), vasthi (enema theraphy), nasya (erffine theraphy) & rakthamokshana (bloodletting) are the pradhana karmas. Raktamokshana (bloodletting) is a parasurgical procedure directed for the treatment of Raktaja roga (blood-borne diseases) along with many surgical diseases. Rakthamokshana is aimed to eliminate vitiated blood from the body, but as a result vitiated pitta also eliminates. [Ariyawansha, 2007]. In today society there are so many diseases which are caused by vitiated raktha & pitta. By rakthamokshana karma can cure these diseases as it eliminates vitiated raktha & pitta. In this research literary review was done primary data collection by Charaka samhitha (Sharma R.K., (2003)1, Susrutha Samhitha (Sharma P.V. (2010)), Astangahrdaya samhitha (Buddhadasa R. (1964), Secondary data collection by publish scientific data (Index journals), Review articles. In survey review details was collected by a standard questionnaire by 30Ayurvedic & traditional doctors who practice in Sri Lanka & by 30 patients who attended to rakthamokshana karma. Finally collected data was analyzed logically by categorization, priorization, observation, Critical analyzation, discussion, conclusion & recommendation. Jalaukächarana is the supreme therapy among all the bloodletting therapies because of its safety and high efficacy, In this study it was observed by practically, literally and scientifically. Also there are significant combination of places which mentioned to blood let and modern science anatomy. This research paper is a sincere effort to analyze Rakthamokshana treatment in Ayurveda & modern aspect.Item An analysis of the barriers of introducing yoga educational program for school students in Sri Lanka(Gampaha Wickramarachchi Ayurveda Institute, University of Kelaniya, 2014) Dissanayake, H.M.N.R.; Samarakoon, S.M.S.Item Analysis of the mandibular molar dental measurements of skeletal remains of prehistoric and recent human populations in Sri Lanka(Gampaha Wickramarachchi Ayurveda Institute, 2009) Chandimal, K.M.; Yasawardena, S.G.; Adikari, G.Item Analysis of the metal content in Ayurvedic medicated oil; Vāthavidurangādī thaila(Young Ayurveda Researchers' and Innovators' Symposium (YARIS – 2019), Institutional Research Committee, Gampaha Wickramarachchi Ayurveda Institute, University of Kelaniya, Yakkala, Sri Lanka, 2019) Jayasinghe, R.N.S.; Weerasooriya, W.M.B.; Rajapakshe, C.S.K.The Ayurvedic medicines of herbo-mineral origin are widely used in Sri Lanka. The metal contamination in such products is frequently reported in recent years. As accumulation of excessive amount of metals in the human body leads to various health hazards, the precise determination of such contaminants is required for safety assurance before usage. The Ayurvedic medicated oil, Vāthavidurangadī Thaila, is a popular medication prescribed by Ayurvedic physicians to treat several diseases and disorders. Therefore, this study was conducted to determine the concentration of selected metals in commercially available samples of Vāthavidurangadī Thaila using Atomic Absorption Spectrometry (AAS). The ten samples of Vāthavidurangadī Thaila collected from Colombo, Kandy, Kalutara, Galle and Gampaha districts were analyzed, for the content of Aluminum (Al), Copper (Cu), Cadmium (Cd), Chromium (Cr) and Lead (Pb) after acid digestion of samples with conc. HNO3 ,H2O2 and 70% HClO4. According to the results, Cu was found in all samples, Cr was detected in six samples but Pb was detected only in four samples. Al, Cu, Cd, Cr and Pb contents in oil samples were found in the range of 0.29-9.54 ppm, 2.34-10.80 ppm, 0.04-0.25 ppm, 3.02-4.39 ppm and 0.98-2.81 ppm respectively. The mean concentration values of Al, Cu, Cd, Cr and Pb were 4.7088 ppm, 4.7844 ppm, 0.0576 ppm, 1.5912 ppm and 0.8568 ppm respectively. The trend of abundance of metals in oil samples of Vāthavidurangadī Thaila followed the sequence of Cu >Al > Cr > Pb >Cd. According to the results, Al and Cr contents in some of the oil samples were higher than the maximum allowable limit recommended by WHO in drinking water. Chromium and Aluminum are not permissible for herbal medicines according to the WHO standards but Cd, Pb, Cu contents in all oil samples were lower than the maximum allowable limit recommended by WHO in herbal medicines.Item Analysis of the properties of Tamalakyadi Kvatha: a critique.(Department of Shalya Shalakya,Gampaha Wickramarachchi Ayurveda Institute,University of Kelaniya,Sri Lanka, 2017) Ranasinghe, R.L.D.S.; Ediriweera, E.R.H.S.S.Tamalakyadi Kvatha is one of the popular decoctions among Ayurveda physicians. It is commonly used for ailments such as Peenasa, Arsha, Shwasa, Kasa and Agnimandya. This comprehensive overview is a step towards analysing Ayurveda pharmacodynamic properties, phytochemical content and bioactivities of the ingredients of Tamalakyadi Kvatha and its utility in the selected diseases. Data were collected from authentic Ayurveda texts and electronic sources. It covers the entire plants of Phyllanthus amarus and Solanum xanthocarpum, pericarp of Terminalia chebula, roots of Solanum trilobatum, Solanum melongina, Adhatoda vasica, Piper chaba and Clerodendrum serrutum, fruits of Piper longum, rhizome of Zingiber officinale, stem of Tinospora cordifolia, and seeds of Piper nigrum. With the predominance of Tikta Rasa (67%), Katu Rasa (67%), Laghu Guna (92%), Ruksha Guna (75%) and Katu Vipaka (50%), Tamalakyadi Kvatha pacies vitiated Kapha Dosha. Due to its Ushna Veerya (75%) it pacies both vitiated Kapha and Vata Dosha. Madhura Vipaka (50%) is capable of pacifying vitiated Pitta Dosha. It also has Deepana (83%), Pachana (83%), Shwasahara (58%), Vatanulomana (58%), Kasahara (50%), Kaphaghna (50%), Jvaraghna (33%) and Sirovirechana (32%) properties. The ingredients are rich with valuable phytochemicals viz; alkaloids, avonoids, glycosides, tannin and volatile oils. These phytochemicals are scientically proven to possess anti-inammatory, anti-cholinergic, antioxidant, antimicrobial, diuretic and hypoglycaemic activities. Therefore, it can be justied that due to its pharmacodynamic properties and bioactivities Tamalakyadi Kvatha can be specically used in the management of Vata Kapha Janya diseases. The administration of this Kvatha is useful in Agnimandya and Arsha since it possesses the properties of Agnivardhaka.Item Analytical study on Navarathna Kalka prepared by classical and conventional methods(Gampaha Wickramarachchi Ayurveda Institute, University of Kelaniya, 2014) Kumara, K.W.D.C.C.; Samarakoon, S.M.S.; Samarathunga, L.M.D.D.K.Item An analytical study on the antimicrobial activity of Visarpahara Tailaya against Candida albicans and Staphylococcus aureus.(Department of Shalya Shalakya,Gampaha Wickramarachchi Ayurveda Institute,University of Kelaniya,Sri Lanka, 2017) Madumali, M.G.B.; Wickramarachchi, W.J.; Karunarathna, E.D.C.; Sudesh, A.D.H.Visarpahara Tailaya is a herbo-mineral preparation recommended to use clinically in the management of eczema, scabies, itches and other types of skin diseases mainly caused by bacteria and fungi. This study was conducted to determine the antimicrobial activity of this drug using the standard Antimicrobial Sensitivity Test against Staphylococcus aureus and Candida albicans. The test was performed according to the Well diffusion Method having 6 mm diameter wells on Mueller Hinton Agar (MHA) for S. aureus and Sabouraud Dextrose Agar (SDA) for C. albicans. As the positive controls, Amoxicillin 10mg/ml was used for S.aureus and Fluconazole 2.5mg /ml for C. albicans. According to the results, the test drug showed an average Inhibition Zone Diameter (IZD) of 12mm for S. aureus and 17mm for C. albicans while the positive controls showed 51mm and 25mm respectively .These results show that the test drug Visarpahara Thailaya is effective for both test organisms with an increased effectiveness for C.albicans compared to S. aureus. Therefore, it is concluded that Visarpahara Tailaya can be effectively used in the management of C. albicans while it is less effective for S. aureus.Item An analytical study to ascertain the usage of Yoga Asana as a supportive measure in management Haemorrhoids(Gampaha Wickramarachchi Ayurveda Institute, University of Kelaniya, 2014) Karandugoda, K.K.I.E.; Perera, B.S.R.Item Ancient native medicine for Leukemia in Sri Lanka(Gampaha Wickramarachchi Ayurveda Institute, University of Kelaniya, 2014) Perera, B.R.P.S.; Perera, B.P.R.Item Antenatal care for reducing ocular and auditory disorders.(Department of Shalya Shalakya,Gampaha Wickramarachchi Ayurveda Institute,University of Kelaniya,Sri Lanka, 2017) Kadam, S.The aim of Garbhini paricharya is to maintain a healthy progeny, i.e., child having long life, good health and fortune, power of supremacy, energy, complexion and healthy sensory organs. Health of all sensory organs (Indriya) of individual can be affected by various factors like Beeja vikriti, diet consumed by mother during antenatal period, consumption of garbhopaghatakarabhavas and diseases occurred during pregnancy. These factors can lead to some disorders of eye or ear, which in turn can affect the whole life of the individual. With the help of Ayurvedic principles, it is possible to prevent from some of these eye and ear disorders to be transmitted to the foetus. For prevention of these disorders, several steps can be followed; preconceptional care, antenatal care and intrapartum and postpartum care. In families having history of eye or ear disorders, preconceptional panchakarma therapy to conception willingcouple and some medicines can be used for preventing transmission of such disorders to the foetus. According to Ayurveda, Indriya utapatti in foetus takes place in the third month and its upachaya in fourth and fth months. During this period, it is important to prescribe specic diet, herbs which can increase the strength of particular organs in order to control some ophthalmic and auditory disorders. An attempt is made in this paper to elaborate the conceptual study of the etiological factors which can affect the functions of eyes and ears. Several measures are suggested to be followed during prenatal and natal period which can increase the strength of these organs and achive Indriyasampannata.Item Anti-bacterial Activity of different extract of Curcuma longa in the management of Fistula in ano(European Journal of Biomedical and Pharmaceutical Sciences, 2017) Pushpakumara, A.A.J.; Jayaratne, D.L; Samaranayake, G.V.P.Ayurvedic parasurgieal treatment procedure Ksharasutra was one of the effective treatment for management of the fistula in ano. Curcuma longa was the one of the main ingredient in a thread. In the present work an attempt hæ; been made to analyn the antibacterial and potential of methanol, ethanol and aqueous extracts of Curcuma longa against E coli S. aureug, Sagalactiae and P_aeruginosa among bacterial strains by disc diffusion method and the antibacterial were determined by masuring the diameter of mne of inhibition. The reports on extraction method using soxhlet extractor The methanol extracts of Curcuma longa p»ssessed the highest antibacterial with a zone of inhibition of 34 mm for, S aureus and lowest 13mm for P. aeruginosa, ethanol extract has range of Of inhibition 3 1 mm-IOmm while lowest antibacterial activities was reported alueous extract range 28mm-l I mm zone Of inhibitionItem Anti-inflammatory and Analgesic activities of Dashana Samskara Churna and its' paste form(Indian Journal of Natural Products and Resources, 2011) Peiris, K.P.P.; Ashok, B.K.; Manjusha, R.; Ravishankar, B.Anti-inflammatory and analgesic activities of Dashana Samskara Chuma and its paste form were examined in different animal models. Anti-inflammatory activity was evaluated in acute, sub-acute and chronic inflammatory models and compared with Phenylbutazone, Diclofenac sodium and Dexomethasone standards, respectively. Analgesic activity was evaluated in formalin induced paw licking (chemically induced pain) and tail flick method (thermally induced pain) where Indomethacin and Pentazocine were used as standard drugs, respectively. Test formulation in the form of paste inhibited the carrageenan induced paw oedema (P<0.05), formalin induced paw licking (PItem Antibacterial Activity of Euphobia antiquorum latex(International Journal of Applied Pharmaceutical Science and Research, 2017) Pushpakumara, A.A.J.,; Jayaratne, D.L.; Samaranayake, G.V.P.Eumorbia antrquorum is a shrub tree Monging to the largest and the rnost family in the plant kingdom. Euphorbiaceae. E emnquram latex was used as a classical binding agent the kshu-a sutra in the management of the anal fistula. In the present study, an attempt made to evaluate the antimicrobial properties of latex Of E. antiquorum on certain microbes. methanolic extract Of the latex prepared. The fractions of methanol extract were tested br their antibacterial activity against the Gram positi•.e bwteria, Streptococus agrlactiæ and aweus Gram negative bacteria Escherichia coli and P. aeruginosa. results revealed that the latex showed minimum inhibition only to E coli and S aureus_ Latex did not antibacterial activity against S agalactiae and P. aerugintßa_ results suggest that the E. anuquorum latex extract account for the antibacterial propcrtics and has a potential use as an antimicrobial agent.Item Antibacterial activity of Kaluduru (Nigella sativa) crude oil against Staphylococci organisms isolated from mastitis cows(Gampaha Wickramarachchi Ayurveda Institute, 2009) Sarjoon, M.A.C.M.; Wijewardana, T.G.; Mahusoon, M.M.Item Antibacterial activity of Maha Thuwāla Thaila against laboratory specimens of Staphylococcus aureus: an experimental study(Young Ayurveda Researchers' and Innovators' Symposium (YARIS – 2019), Institutional Research Committee, Gampaha Wickramarachchi Ayurveda Institute, University of Kelaniya, Yakkala, Sri Lanka, 2019) Thiwanthika, U.A.C.; Vitharana, P.Ayurveda and indigenous herbal preparations are used in the treatment of various types of infectious wounds. They are composed of many herbs which naturally contain anti-microbial compounds. They can be effectively used against bacterial and fungal infections. Maha Thuwāla Thaila is a medicine for external application which is mostly used in indigenous medicine in Sri Lanka to cure chronic wounds, cut-injury wounds, orthopedic wounds and burned wounds. In addition, this oil preparation is clinically used in orthopedic treatment (Sandi Baghna Cikitsa) to cure Sandi Baghna. It consists of many herbs, oils, spices and minerals which have a number of anti-bacterial and anti-fungal compounds. Generally, all types of skin wounds are colonized by various types of bacteria. Common among these bacteria types is Staphylococcus aureus which is considered the classic opportunist bacteria which takes advantage of broken skin or other entry sites to cause an infection. But efficacy of this oil against Staphylococcus aureus in wounds is not scientifically evaluated. The purpose of this study was to evaluate tthe ant-bacterial activity of Maha Thuwāla Thaila against the laboratory specimen of Staphylococcus aureus by using Anti-bacterial Susceptibility Test (ABST). In this study Amoxicillin (5 mg/ml) was used as a positive control. The tested oil sample has shown 8.83 mm mean inhibitory zone diameter while positive control showed 39.33 mm of mean diameter. This result concludes that the tested samples of Maha Thuwāla Thaila showed less significant anti-bacterial activity against the laboratory specimens of Staphylococcus aureus bacteria under these laboratory conditionsItem Antibacterial activity of two different Prathisaranas against periodontitis.(Department of Shalya Shalakya,Gampaha Wickramarachchi Ayurveda Institute,University of Kelaniya,Sri Lanka, 2017) Abegunasekara, N.S.; Peiris, K.P.P.; Sudesh, A.D.H.'Kushtaadi Choorna and Shwethamanjana Choorna' are used in the treatment ofDanthamulagatha Roga such as Sheethada, Danthaweshta and Upakusha. These formulations are used specially as a local treatment. Staphylococcus aureus and Methicillin resistant Staphylococcus aureus (MRSA) are main causative organisms of periodontal diseases. The present study was carried out to determine the antibacterial activity of Kushtaadi choorna andShwethamanjana choorna using agar well diffusion method in comparison with standard antibiotic Amoxicillin against the Staphylococcus aureus (ATCC 25923) and Methicillin resistant Staphylococcus aureus (MRSA). The samples of Prathisarana were prepared in ne powder form, Amoxicillin as positive control and triplicates were made for each test. Observation was recorded by measuring the diameter of the inhibitory zones surrounding the wells. According to the results, inhibitory effect of both Prathisarana samples were signicantfor Staphylococcus aureus and Methicillin resistant Staphylococcus aureus (MRSA).Item Antimicrobial Efficacy of Selected Ayurveda Formula against Laboratory Specimen of Staphylococcus aureus(International Journal of Scientific and Research Publications, 2020) Dissanayake, K.G.C.; Karunarathna, S. B. M. M. M.Selected formula consisted of tllree ingredients including dried leaves of Azadirachta indica, dried seeds of Sesamum indicum and Bees' honey which is clinically use for open wounds. The current study was designed as a microbiological assay and the key objective was to evaluate the antibacterial efficacy of TNK against laboratory specimen of Staphylococcus aureus (ATCC25923). The Anti-Bacterial Sensitivity Test was conducted according to the Kirby Bauer method using Agar Well Diffusion method by comparing the effect of Amoxicillin as the positive controller and distilled water as the negative controller in triplicates. The testing drug was assessed as DI and D2 in concentration ratios respectively. Results of the study were obtained through the diameter measurement of inhibitory zone and assessed using one - sample T — test DI depicted p value as 0.024 and T - test was 4.44. D2 depicted p value as 0.100 and T- test was 1.89. Comparing to the positive control drug, the hypothesis was generated as Ho: μ ≤19 mm and H1 : μ>19 mm Referring to hypothesis, Hoof DI was rejected and HoofD2 was not rejected. The significant level was considered less tllan 5%. D2 concentration of TNK was significant against laboratory specimen of Staphylococcus aureus_ The study suggests that the TNK is consisted with an extrinsic effective antibacterial application for infected wounds which were caused by Staphylococcus aureus_ Further clinical study on human subjects will verify the efficacy of TNK in clinical manifestations.Item Antipoisonous (vishaghana) effect of Ghee: a review(Gampaha Wickramarachchi Ayurveda Institute, University of Kelaniya, 2014) Wijesinghe, W.A.M.S.; Karandugoda, K.K.I.E.