Medicine
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This repository contains the published and unpublished research of the Faculty of Medicine by the staff members of the faculty
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Item The characteristics of people with diabetes mellitus in Kalutara District(Sri Lanka Medical Association, 2010) de Silva, A.P.; de Silva, S.H.P.; Rajapakse, L.C.; Jayasinghe, S.; Katulanda, P.; Wijeratne, C.N.; Wijeratne, S.INTRODUCTION AND OBJECTIVES: Diabetes mellitus is on the rise. Although recent studies are available data on ethnic minorities and estate sector are scarce. Aim of this study was to describe selected socio demographic aspects of people with diabetes mellitus in Kalutara District. METHODS: A cross sectional descriptive study was done. One person randomly selected from 20 randomly selected households in each gramasevaka (GS) division. There were 65 random (GS) divisions from all divisional secretariat areas. The data were collected using a pre-tested standard questionnaire. Fasting blood sugar was done to detect diabetes mellitus. RESULTS: Among 1225 screened there were 205 (16.7%) diabetics. Approximately one third was newly detected. There were 107 (52.2%) females in the diabetic group. The highest proportion was observed in the 50-54 and 55-59 age groups (44, 21.5%) and the middle income group (93, 48.9%). Those who were educated from Grade 6 to 0/L contained most of the diabetic patients (75, 39.7%). The prevalence in the urban, rural and estate sectors were 25.5%, 15.5 and 9.2% respectively. The prevalence among Sinhalese, Tamils and Muslims were 19.0%, 9.0% and 22.4% respectively. A gradient can be observed when prevalence was graphed according to the unsatisfactory basic needs index of the GS divisions. The highest proportion (23%) was observed in the richest GS Division. CONCLUSION: The prevalence of diabetes mellitus is high in the Kautara District. A higher prevalence was observed in urban areas, among Muslims and in rich GS divisions.Item The burden of diabetes mellitus in an urban population of Sri Lanka(Sri Lanka Medical Association, 2011) Pinidiyapathirage, M.J.; Kasturiratne, A.; Williams, S.; Wijekoon, N.; Pathmeswaran, A.; Ranawaka, U.K.; Warnakulasuriya, T.; Takeuchi, F.; Kato, N.; Wickremasinghe, A.R.INTRODUCTION AND OBJECTIVES: To describe the burden of diabetes in middle and old aged residents (35-64 years) in an urban area of Sri Lanka. METHODS: A cross-sectional survey was conducted in the Ragama Medical Officer of Health area, in which 2986 participants (1349 men and 1637 women) were randomly selected from the electoral registry between January and December 2007. The participants underwent a physical examination and had their height, weight, waist and hip circumferences and 51ood pressure measured by trained personnel. Blood samples were taken after a 14 hour fast for measurement of glucose, HbAlc and lipids. The prevalence of diabetes (fasting plasma glucose [FPG] >7mmol/L) and impaired fasting glycaemia [IFG] (FPG=5.6-6.9mmol/L) and major predictors of diabetes in Sri Lanka were estimated from the population based data. RESULTS: In the whole sample two thirds of the participants were diagnosed as either people with diabetes (20%) or IFG (45%). Among the diabetics only 23.8% were optimally controlled. Through the present screening, 235 diabetics (7.9%) and 1257 (42.1%) participants with impaired fasting glucose levels were newly identified. Old age (OR=5.1, 55-64 years vs. 35-44 years), male sex (OR=3.1), family history (OR- 2.7), central obesity (OR-1.8), and reduced physical activity (OR=1.3) were significantly associated with increased risk of diabetes. CONCLUSIONS: Our data demonstrate the heavy burden of diabetes in the general population. Short and long term control strategies are required not only for optimal-therapy among those affected but also for nationwide primary prevention of pre-diabetes.