Medicine
Permanent URI for this communityhttp://repository.kln.ac.lk/handle/123456789/12
This repository contains the published and unpublished research of the Faculty of Medicine by the staff members of the faculty
Browse
2 results
Search Results
Item Review of the cervical cancer screening programme in the Puttalam district(Sri Lanka Medical Association., 2019) Fernando, Y.K.J.; Pathmeswaran, A.INTRODUCTION & OBJECTIVES: A well implemented screening programme is effective in preventing cervical cancer. ln order to improve programme effectiveness all programmes need to be reviewed periodically. The objective of this study was to review the cervical cancer screening program in Puttalam District. METHODS: Cross sectional descriptive study was done in 2015. Primary and secondary data was collected using data collection sheets, self-administered questionnaires and structured interviews from all stake holders involved in cervical cancer screening program in Puttalam District. RESULTS: Adequate number of clinics were available considering clinic to population ratio of 1: 15000 as the norm, but vacant positions existed in all staff categories. Colposcopes were unavailable and zero stock episodes of consumables were noted at MOH level. Target age group (35 years) Pap smear coverage, number of cervical visualizations, pap smears taken and positive pap smears were indicators used to monitor the programme. Positive cervical cytology reporting time was more than 10 weeks (mean was 72 days, range 2-334). Guidelines relating to quality control; obtaining a pap smear & cytology process and documentation regarding process of follow up care were not available. Coverage of target age group women (35 years) increased from 28.4% (2013) to 32.4 % (2015). Number of cervical cancers prevented could not be calculated as follow-up information was not available. CONCLUSION: Human resources and equipment relating to pap smear screening need improvement. Indicators sensitive to target population; cytology report turn-around time, and quality indicators need to be built in to program, guidelines developed and evaluated. Outcome of screened positives should be followed up and documented.Item Distribution of human papillomavirus genotypes in archival cervical tissue from women with cervical cancer in urban Sri Lanka(Elsevier, 2011) Samarawickrema, N.A.; Tabrizi, S.N.; Hewavisenthi, J.; Leong, T.; Garland, S.M.OBJECTIVE: To identify the contributions of various human papillomavirus (HPV) genotypes in tissue samples from women diagnosed with cervicalcancer in Sri Lanka. METHODS: In a retrospective study, archival cervical tissues samples (n=108) obtained from Sri Lankan women diagnosed with histologically proven invasive squamous cell carcinoma between 2006 and 2007 were tested for HPV. Genotyping of HPV DNA was performed using an INNO-LiPA assay. RESULTS: Overall, 93% of tumor samples tested positive for HPV DNA. HPV types 16 and 18 accounted collectively for 83.4% of the positive samples. CONCLUSION: The findings suggest that the HPV genotypes responsible for causing cervical cancer in Sri Lanka are similar to those reported elsewhere worldwide. Consequently, women in Sri Lanka could benefit from currently available prophylactic HPV vaccines should they be implemented.