Medicine
Permanent URI for this communityhttp://repository.kln.ac.lk/handle/123456789/12
This repository contains the published and unpublished research of the Faculty of Medicine by the staff members of the faculty
Browse
4 results
Search Results
Item Psychometric validation of the In-hand manipulation assessment (IHMA)(W.B. Saunders, 2024-11) Liu, K.P.Y.; Chapman, A.; Tsoi, T.L.Y.; Thach, P.; Welage, N.; Tulliani, N.OBJECTIVE To determine the inter-rater reliability, and criterion and discriminant validity of the In-Hand Manipulation Assessment (IHMA) with patients after stroke.DESIGN Participants were videotaped, completing the IHMA and scored by 2 blinded assessors to determine the inter-rater reliability. Stroke participants also completed the Jebsen-Taylor Hand Function Test, and healthy participants completed the Nine-Hole Peg Test to determine the validity of the IHMA.SETTING Community and hospital settings.PARTICIPANTS A total of 46 participants with 22 healthy young adults, 14 healthy older adults and 10 people with stroke.INTERVENTIONS Not applicable.MAIN OUTCOME MEASURES Not applicable.RESULTS The inter-rater reliability of the IHMA was good (for all participants: intraclass correlation coefficient = 0.78-0.98, P≤.001; for stroke participants: Kappa statistics = 0.70-1.00, P≤.001). The IHMA demonstrated good discriminant validity between the healthy young adults and healthy older adults for time and completion scores (Ps=.012 and ≤.001). The criterion validity of the IHMA was moderate to good when compared with the Nine-Hole Peg Test (r = -0.45 to 0.84), but no significant correlation was found with the Jebsen-Taylor Hand Function Test. Modifications to the IHMA tasks and instructions were made based on the performance of participants to improve its clinical utility with people after stroke.CONCLUSIONS The IHMA demonstrated good inter-rater reliability, good discriminant validity, and moderate-to-good criterion validity with the Nine-Hole Peg Test. The proposed modifications to the IHMA will enhance its administration.Item Development and assessment of psychometric properties of model medication adherence (MMA) questionnaire to measure adherence to oral medication among patients with type 2 diabetes mellitus(College of Community Physicians of Sri Lanka, 2023) Perera, S.; Abeysena, C.INTRODUCTION: Medication adherence among patients with type 2 diabetes (DM) is assessed in everyday clinical practice. OBJECTIVES: To develop a questionnaire to measure adherence to oral medication among patients with DM and to assess its psychometric properties METHODS: The “Model Medication Adherence (MMA)” questionnaire was developed using the evidence from literature review and interviews with key stakeholders and patients. Answers were set on a five-point Likert scale that scored from 1 to 5, with 15-73 as the possible range of the total score. MMA was drafted in English and translated to Sinhala language by forward- backward translation. A descriptive cross-sectional study was carried out among adult patients with type 2 DM who attended clinics in Gampaha District General Hospital (DGH). A sample of 150 patients was recruited consecutively. The construct validity of MMA was assessed by Exploratory Factor Analysis (EFA) through Principal Component Analysis (PCA) with Varimax rotation RESULTS: EFA yielded four factors; sick role behaviour, autonomy, forgetfulness, and barriers that explained 64.36% of the variance of the total score of MMA. Internal consistency was acceptable (Cronbach’s alpha 0.73). The testretest reliability coefficient was 0.85 (p=0.01). Acceptability of the MMA was established by non-response items (none) and the time taken to complete (20 minutes). CONCLUSIONS & RECOMMENDATIONS: MMA is a simple valid questionnaire that adds a novel concept to the adherence literature; sick role and autonomy. It has a good factor structure with established construct validity and is recommended to be used in the clinical setting.Item Cross-cultural adaptation and validation of the Leibowitz Social Anxiety Scale (LSAS-SR) sinhala version(Sri Lanka Medical Association, 2020) Hapangama, A.; Kuruppuarachchi, L. A.; de Silva, R.; Wickremasinghe, A.R.; Ravindran, A.; Williams, S. S.No abstract availableItem Association between road accidents and low-grade hepatic encephalopathy among Sri Lankan drivers with cirrhosis: a prospective case control study(Biomed Central, 2016) Subasinghe, S.K.C.E.; Nandimuni, Y.; Ranasinghe, S.; Niriella, M.A.; Miththinda, J.K.N.D.; Dassanayake, A.S.; de Silva, A.P.; de Silva, H.J.BACKGROUND: Low-grade hepatic encephalopathy (LGHE) comprises minimal hepatic encephalopathy (MHE) and grade 1 hepatic encephalopathy. LGHE has no or minimal recognizable symptoms but has mild cognitive and psychomotor deficits. Studies in Western countries have demonstrated increased road accidents (RA) among patients with MHE. Our objective was to investigate the association between Sri Lankan LGHE phenotype and RA. STUDY DESIGN AND METHODS: A prospective, case–control study was conducted in the University Medical Unit, North Colombo Teaching Hospital, Ragama Sri Lanka. Patients with cirrhosis of any aetiology, without OHE, who had been driving during previous 1 month were included. A similar number of age matched, healthy control drivers were also enrolled. Both groups were subjected to five pencil-paper based psychometric tests used to detect LGHE in cirrhotics. Self-reported RA during the previous 1 month were recorded: categorized as ‘major’ when resulted in hospitalization of the involved, ‘minor’ when there were injuries, but not serious enough for hospitalization of the involved and ‘other’ when limited to damages to vehicle or environment without injuries. RESULTS: Among 55 drivers with cirrhosis and LGHE [males, median age 53 years (range 30–60)], 7 (12.7 %) reported RA compared to 6 (10.9 %) among 55 controls [males; median age 51 years (range 30–60)]. There were no ‘major’ accidents in either group. 2/55 (3.6 %) cases and 2/55 (3.6 %) controls reported ‘minor’ accidents. CONCLUSION: There was no increased frequency of RA among Sri Lankan drivers with LGHE compared to healthy controls. This is with the limitation of the study based only on self reported RA.