Medicine
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This repository contains the published and unpublished research of the Faculty of Medicine by the staff members of the faculty
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Item Effect of Mindfulness Meditation on Symptoms of Stress and Depression in Cancer outpatients of Sri Lanka. (MeSADISC study)(Ibn Sina Medical College, 2025-01) Dayasiri, K.; Rajapakshe, D.; Goonewardane, N.D.V.; Jayarathne, COBJECTIVES This intervention study aimed to evaluate mindfulness meditation as a method of treatment for cancer outpatients for stress reduction and control of symptoms of depression and to find out effects of socio demographic differences.METHOD Cancer outpatients were randomly selected on separate clinic dates at the National Cancer Institute of Sri Lanka and were enrolled as cases (n=44) and controls (n=30). Volunteers followed training sessions once weekly in addition to home based mindfulness meditation. All participants were asked to complete the “Beck’s Depression” and “Symptoms of Stress” questionnaires prior to intervention and at each session. Controls were assessed based on the identical questionnaire at start and end of 9 weeks. Both groups were heterogeneous in age, sociodemographic characteristics and cancer types / stage.RESULT At the end of the intervention, patients in the intervention group had significantly lower scores of depressions and stress. Reduction in Beck’s depression score was from 33.21 to 24.56 (p<0.001) in the treatment group, compared to 34.5 to 32.34 (p>0.05) in the control group. Reduction in Symptoms of Stress Inventory from 21.21 to 10.76 (p<0.001) was seen in the intervention group, compared to 22.50 to 25.5 increase in controls. Significant changes (p<0.05) were seen in all age categories, gender, education, income and levels of social interactions.CONCLUSION Mindfulness meditation programme was effective in decreasing levels of depression and stress in people with cancer, irrespective of socio-demographic backgrounds and cancer types or stages.Item Effectiveness of anapana, body scan and metta meditation techniques on chronic neck and shoulder region pain and disability in adult patients in Sri Lanka: study protocol for a cluster clinic-level randomised controlled trial(BioMed Central, 2022) Karunanayake, A.L.; Solomon-Moore, E.; Coghill, N.Background: Chronic neck and shoulder region pain affects many people around the world. This study aims to compare the effectiveness of three 8-week meditation training programmes (each using a different meditation technique: Anapana, Body scan or Metta) on pain and disability in a patient population affected with chronic neck and shoulder region pain, with a usual care control group and with each other. Methods: This four-arm parallel clinic-level randomised controlled trial will be conducted with male and female patients aged 18-65 years, who are affected with chronic neck and shoulder region pain, and who attend one of four clinics held on four different days of the week in a single medical centre in the Colombo North region, Sri Lanka. Clinics will be considered as clusters and randomly allocated to intervention and control arms. Data will be collected using validated questionnaires, clinical examinations and focus groups. To compare primary (differences in changes in pain (Numeric Pain Rating Scale) at 8 weeks) and secondary (differences in changes in pain, physical disability, range of movement and quality of life (SF-36) at 4 and 12 weeks) outcomes between groups, a two-way ANOVA will be used if data are normally distributed. If data are not normally distributed, a nonparametric equivalent (Kruskal-Wallis) will be used. Focus group transcriptions will be thematically analysed using the Richie and Spencer model of qualitative data analysis. Discussion: This is a four-arm trial which describes how three different 8-week meditation technique (Anapana, Body Scan, Metta) interventions will be implemented with adult patients affected with chronic neck and shoulder region pain. The effectiveness of each meditation intervention on the pain, physical and psychosocial disabilities of patients will be compared between groups and with a usual care control group. The results of this study will contribute to recommendations for future meditation interventions for chronic neck and shoulder pain.