Medicine
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This repository contains the published and unpublished research of the Faculty of Medicine by the staff members of the faculty
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Item Profile of paediatric respiratory diseases requiring hospital admission(Sri Lanka Medical Association, 2012) Subasinghe, V.; Karunasekera, W.; Fernando, A.D.; Lakmini, C.; Weerasooriya, L.; Hathagoda, W.INTRODUCTION: Respiratory tract disorders cause significant mortality and morbidity in children worldwide. OBJECTIVES: To study the pattern of respiratory diseases and its seasonal variation among children. METHODS: A descriptive study was conducted at University Paediatric Unit, Colombo North Teaching Hospital in 2010 and 2011. All children below 12 years admitted with respiratory tract diseases (ICD-10 classification) were recruited into the study. Data collection forms were filled by medical officers using patient records. RESULTS: Total of 2651 (1370 in 2010; 1281 in 2011) were admitted with respiratory diseases. In respective years, 53% (2010) and 55%(2011) were males. Highest number of admissions was during infancy (27.2%). During consecutive years 2010 and 2011, 43.0% and 45.2% had unspecified lower respiratory tract infections (LRT1); 29.9% and 29.4% had upper respiratory tract infections (URTI); 10.7% and 12.4% had bronchial asthma; 1.8% and 2.2% had pneumonia; 5.9% and 8.9% had bronchiolitis. Stabilization at ETU was needed in 8.5%. Median duration of hospital stay was 3 (range 1-60) days. No follow-up was required in a majority (82.5%). Admissions due to respiratory diseases peaked in June (2010-20.1% and 2011-16.0%) and were mainly due to LRTI-52.0%, URTI-28.4%. Admissions with bronchial asthma were higher during the first half of the year (2010-86.3% and 2011-80.5%). Deaths were 18 (1.3%) in 2010 and 6 (0.5%) in 2011. CONCLUSIONS: Respiratory tract infections peak in June whereas asthma is precipitated in early months of the year. Over one-fourth of patients had URTI and was unnecessarily admitted.Item Knowledge and attitudes on Cervical Cancer and Its prevention amongst primigravid women(Sri Lanka Medical Association, 2014) de Silva, A.H.W.; Kasturiratne, A.; Subasinghe, V.; Samarawickrema, N.; Garland, S.M.; Wickremasinghe, A.R.INTRODUCTION AND OBJECTIVES: To describe knowledge and attitudes on cervical cancer and its prevention amongst primigravid women METHODS: A descriptive cross-sectional study was conducted amongst primigravid women aged 18-35 years attending the antenatal clinics of Colombo North Teaching Hospital in 2013. Data were collected using a pretested self-administered questionnaire on their booking visit. RESULTS: 667 participated in the study. Mean age (SD) was 23.9 (4.4) years. Majority (67.5%) had passed G.C.E. Ordinary Level. 30% had heard about cervical cancer but only 11% knew of its viral aetiology.40% identified cervical cancer as a common cancer in Sri Lanka. 8% considered it to be familial and only 15% knew its transmissibility through sex. Knowledge on human papilloma virus (HPV) was very low. 9% had heard about the Papanicolaou test while only 50% of them knew that it could detect cervical cancer at a treatable stage. Only 5.4% had heard about HPV and 5.8% about a vaccine against HPV. Of the respondents who have heard about HPV 70% (21/39) knew that the infection can be prevented by a vaccine.10.5% strongly accepted undergoing periodical Papanicolaou tests as a good health practice while 45% did not know to comment. 21% had no fear but 5% felt embarrassed to participate in testing. Oniy 21% accepted it as a safe test. The association between the level of education and the knowledge of public health importance of cervical cancer was statistically significant (p=0.02). CONCLUSIONS: Knowledge on cervical cancer and preventive methods are low amongst primigravid women. Attitude towards the Papanicolaou test is poor.Item Association between child maltreatment and constipation: a school Based survey using Rome III Criteria(Lippincott Williams and Wilkins, 2014) Rajindrajith, S.; Devanarayana, N.M.; Lakmini, C.; Subasinghe, V.; de Silva, D.G.H.; Benninga, M.A.Child abuse leads to multiple physical and psychosomatic sequelae. The aim of the present study was to evaluate the association between child abuse and constipation among schoolchildren. METHODS: Children 13 to 18 years of age were selected from 4 semiurban schools in Gampaha District, Sri Lanka. A self-administered questionnaire was used for data collection. Information regarding socio demographic factors and gastrointestinal symptoms, child abuse, and somatisation were collected. Constipation was diagnosed using Rome III criteria. RESULTS: A total of 1792 children were included in the analysis (boys 975 [54.4%], mean age 14.4 years, standard deviation [SD] 1.3 years). One hundred thirty-eight (7.7%) fulfilled Rome III criteria for constipation. The number of children exposed to physical, emotional, and sexual abuse were, respectively, 438 (24.4%), 396 (22.1%), and 51 (2.8%). The prevalence of constipation was significantly higher in those exposed to sexual (5.8% vs 2.6% P = 0.03), emotional (40.9% vs 20.8%, P < 0.0001), and physical abuse (41.6% vs 23.2%, P < 0.0001). Mean somatisation score was higher in the total group of abused children with constipation (mean 18.6, SD 12.5) compared with those without (mean 13.9, SD 12.3; P = 0.027). Children with a history of abuse did not seek health care more often than children without this history. Patient-perceived severity of bowel symptoms was higher in children with physical abuse (23.7 vs 19.7 P = 0.001) and emotional abuse (25.4 vs 19.3 P < 0.0001). CONCLUSIONS: Childhood constipation shows a significant association with physical, sexual, and emotional abuse. Children with constipation complain of more somatic symptoms and bowel symptoms when they are exposed to abuse.