Medicine
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This repository contains the published and unpublished research of the Faculty of Medicine by the staff members of the faculty
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Item Validation of the Tamil translation of the International Consultation on Incontinence modular Questionnaire on Vaginal Symptoms (ICIQ-VS)(Sri Lanka College of Obstetricians & Gynaecologists, 2016) Ekanayake, C.D.; Wijesinghe, P.S.; Pathmeswaran, A.; Samaranayake, K.U.; Herath, C.; Nishad, A.A.N.OBJECTIVES: To translate and validatethe International Consultation on Incontinence Modular Questionnaire on vaginal symptoms (ICIQ VS) from English to Tamil. METHOD: With permission, ICIQ-VS questionnaire was translated to Tamil and a validation study was done on women attending the gynaecology clinics at district general hospitals, Mannar and Vavuniya. RESULTS: The basic characteristics of women with prolapse (n=63) versus women without prolapse (n=83) were as follows; age 60.68 (SD 11.64), median parity=4 (IQ1-IQ3=3-5), BMI 23.90 kg/m2 (SD 3.36) versus age 40.49 (SD 12.54), median parity=2(IQ1IQ3=1-3), BMI 25.84 kg/m2 (SD 4.84) respectively. Content validity was assessed by the level of missing data which was less than 3% for each item. Internal consistency as assessed by Cronbach’s coefficient alpha score was 0.83 (0.80-0.84). Kappa values for test–retest reliability of individual items ranged from0.59 to 0.74. The questionnaire differentiated between patients and controls in vaginal symptoms score(VSS) (P<0.001), sexual symptoms score(SSS) (p<0.05) and quality of life p<0.001). There was a positive correlation between pelvic organ prolapse quantification system (POP-Q) scores and VSS (rs= 0.67, p<0.001), SSS (rs= 0.26p<0.05) and quality of life (rs = 0.62, p<0.001).Vaginal symptoms (n=24) and quality of life (n=21) showed an improvement following surgery(Wilcoxon matched– pairs signed-rank test p<0.001 and p<0.001 respectively). CONCLUSION: The preliminary results for ICIQ VS (Tamil) validation are satisfactory and once completed it will be invaluable to objectively assess vaginal and sexual symptoms in Tamil speaking population in Sri LankaItem Translation and validation of ICIQ-FLUTS for Tamil-speaking women(Springer, 2017) Ekanayake, C.D.; Pathmeswaran, A.; Nishad, A.A.; Samaranayake, K.U.; Wijesinghe, P.S.AIMS: Research in to lower urinary tract symptoms (LUTS) in women in South Asia is hampered by lack of validated tools. Our aim was to validate the International Consultation on Incontinence Modular Questionnaire on Female Lower Urinary Tract Symptoms (ICIQ-FLUTS) from English to Tamil. METHOD: After translation to Tamil, a validation study was carried out among women attending the gynecology clinic at District General Hospital-Mannar. RESULTS: Content validity assessed by the level of missing data was <2%. Construct validity was assessed by the ability of the questionnaire to identify patients with incontinence (n = 45) from controls (n = 93) using the incontinence score [patients = 7.7 standard deviation (SD) = 4.7, controls = 1.4 SD = 2.2, p < 0.001] and those with symptomatic anterior wall prolapse (n = 16) from controls (n = 93) using voiding symptoms score (patients = 4.8 SD = 2.3, controls = 0.3 SD = 0.8, p < 0.001). Internal consistency was assessed using Cronbach's coefficient alpha score [0.80 (0.77-0.81)]. Test-retest reliability assessed by weighted kappa (κ) ranged from 0.73 to 0.87. Patients with incontinence (n = 30, pretreatment incontinence score = 7.9, SD = 4.9 versus posttreatment incontinence score = 3.3, SD = 3.1) and symptomatic anterior wall prolapse (n = 14, preoperative voiding symptoms score = 4.9 SD = 2.5 versus postoperative voiding symptoms score = 0.9 SD = 1.5) showed an improvement with treatment (Wilcoxon matched--pairs signed-rank test p < 0.001 and p < 0.01, respectively). An incontinence score ≥ 3 (sensitivity = 86.7%, specificity = 78.4%) and a voiding symptoms score ≥ 3 (sensitivity = 87.5%, specificity = 96.2%) detected any form of incontinence and symptomatic anterior wall prolapse, respectively. CONCLUSION: Tamil translation of ICIQ-FLUTS retained the psychometric properties of the original English questionnaire and will be an invaluable tool to detect LUTS among Tamil-speaking women.