Medicine
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This repository contains the published and unpublished research of the Faculty of Medicine by the staff members of the faculty
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Item Validity of the Sinhala version of the general health questionnaires item 12 and 30: Using different sampling strategies and scoring methods(Ibn Sina Academy of Medieval Medicine & Sciences, 2016) Abeysena, H.T.C.S.; Jayawardana, P.L.; Peiris, M.U.P.K.; Rodrigo, A.OBJECTIVE: To determine the criterion validity of the Sinhala version of the General Health Questionnaire-12 (GHQ-12) and GHQ-30 employing different sampling designs and scoring methods. METHODS: This was a descriptive cross-sectional study including 374 patients. The GHQ-30 was completed by the participants using likert scale and then converted into standard score. The ‘Clinical Examination’ was done blindly to the GHQ score as the reference standard. Total study sample was considered as a representative sample taken consecutively. Case-reference design included 126 cases and 126 randomly selected controls based on reference standard. Test result-based designs included two groups of positive and negative GHQ, based on the optimal cut-off level. Cut-off levels were determined by using three criteria. In addition stratum specific likelihood (SSLR) ratio also considered. RESULTS: Applying consecutive sampling design, for the GHQ-12, the optimal cut-off levels were 9/10 using likert score and 2/3 using standard score and for the GHQ-30, 25/26 using likert score and 6/7 using standard score. The optimal cut-off level depends on the different sampling designs employed in addition to criteria for determining cut-off levels. The SSLR of>1 was useful for determining optimal cut-off level. Irrespective of the scoring methods, application of case-reference design tends to be overestimation of the specificity with high threshold values and test result-based design tends to be overestimation of the sensitivity, compared to consecutive sampling. Using likert scoring method, the sensitivities were higher than standard scoring method. CONCLUSIONS: The optimal cut-off levels depend on the sampling design and the scoring method employed and criteria to determine cut-off levels.Item Validation of Kessler's psychological distress scale among the Sinhalese population in Sri Lanka(SAARC Psychiatric Federation, 2011) Wijeratne, L.T.; Williams, S.S.; Rodrigo, M.D.A.; Peiris, M.U.P.K.; Kawamura, N.; Wickremasinghe, A.R.OBJECTIVE: Kessler's psychological distress scales, KlO and K6 are short rating scales designed to screen psychiatric morbidity in the population. Despite being increasingly popular elsewhere, they have not been validated in Sri Lanka. We examined the validity of these scales among the Sinhala speaking population in the Gampaha district of Sri Lanka. DESIGN: The English language version of the KiD and K6 questionnaire were translated into Sinhala using standard methods. The KiD and K6 scores for 27 healthy and 37 psychiatrically ill individuals were compared with the Structured Clinical Interview for DSM disorders (SClD) outcome categories. RESULTS: The KiD and K6 were sensitive and specific in detecting mental illness, especially depression. Those with schizophrenia had scores similar to healthy individuals. We suggest cut offs of 12 for KiD and 7 for K6 having 9D% sensitivity and 81% specificity for both scales. INTERPRETATION: KiD and K6 are valid screening tools for non-psychotic psychiatric illness among the Sinhala speaking population in Sri Lanka. They can be used in psychiatric epidemiological studies.