Medicine

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Recurrent posterior reversible encephalopathy syndrome in a patient with focal segmental glomerulosclerosis: A case report
(EDORIUM Journals, 2016) Luke, N.V.; Wickramasinghe, S.S.; Ranawaka, U.K.
Introduction: Posterior reversible encephalopathy syndrome (PRES) is a rare clinical syndrome of which the aetiology and pathogenesis still remain unknown. We present a rare case of recurrent PRES in a patient with adult onset nephrotic syndrome due to focal segmental glomerulosclerosis (FSGS). Case Report: A 30-year-old Asian female with FSGS on renal biopsy developed two episodes of PRES with residual neurological deficits without significant hypertension. Both these episodes were preceded by initiation of treatment with calcineurin inhibitors for persistent proteinuria. She was subsequently started on mycophenolate mofetil without further recurrences of PRES. Conclusion: Although PRES is well recognized, this case has a combination of several unusual features that merit special attention.