Medicine
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This repository contains the published and unpublished research of the Faculty of Medicine by the staff members of the faculty
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Item Recurrence of graft steatosis after liver transplantation for cryptogenic cirrhosis in recently commenced liver transplant program(Springer India, 2016) Siriwardana, R.C.; Niriella, M.A.; Dassanayake, A.S.; Liyanage, C.A.H.; Gunetilleke, B.; de Silva, H.J.Non-alcoholic fatty liver disease (NAFLD) seems to recur in at least one third of patients transplanted for non-alcoholic steatohepatitis (NASH)-related cirrhosis. While, NASH recurrence does not seem to affect overall graft and patient survival up to 10 years, cardiovascular and infection-related morbidity and mortality seem to be increased in these patients. This report looks at the graft histology in patients who were transplanted for NASH-related cirrhosis after short-term follow up. We report a high prevalence of recurrent NAFLD in liver grafts post-transplant among five patients. The degree of steatosis noted among the recipients is alarming.Item Reconstruction of the middle hepatic vein in live donor liver transplantation: will it improve donor liver function?(College of Surgeons of Sri Lanka,, 2014) Liyanage, C.A.H.Right liver graft with the middle hepatic vein sometimes induces postoperative liver failure in donors due to insufficient functional remnant liver volume. Venous drainage of the graft is important for prevention of congestion and proper function of the graft. Therefore right hepatic veins and the tributaries of the middle hepatic vein need reconstruction. The unique technique of reconstructing the middle hepatic vein, the right hepatic vein and the short hepatic veins using allografts and artificial grafts are discussed. Patients who had right hepatic and middle hepatic vein reconstructions had good graft functions and less hepatic congestion. This technique will be useful for preserving liver function in right liver lobe donors in Sri Lanka where more than 31% of the general population has fatty liver disease.