Medicine
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This repository contains the published and unpublished research of the Faculty of Medicine by the staff members of the faculty
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Item Snakebite in children: a two year retrospective review of victims admitted to a tertiary care hospital in sri lanka(Sri Lanka College of Paediatricians, 2010) Jayasinghe, Y.C.; Kasturiratne, A.; Rajindrajith, S.; Samaraweera, S.A.S.G.; de Silva, H.J.INTRODUCTION: Snakebite is an incident which causes great parental concern and medical unease, and envenomation is always more serious in a child. OBJECTIVE: To determine the pattern and characteristics of snake bites in children admitted to a tertiary care hospital in Southwest Sri Lanka. DESIGN, SETTING AND METHOD: A retrospective descriptive study was conducted to collect data on circumstances of the bite, clinical manifestations and management of paediatric victims of snakebite. Patient records of children admitted to the paediatric wards of Colombo North Teaching Hospital, Ragama, from January 2008 to December 2009 were reviewed. RESULTS: Our study population comprised 41 children (1.6 per 1000 admissions). Malerfemale ratio was 23:18. Mean age was 6 (SD=3.46) years. The bites were definite in 4 subjects and circumstantial (fang marks, signs of local and systemic envenomation) in the others. Twenty five (61%) were between 5 to 12 years of age. Nine (22%) bites occurred indoors and 13 (31.7%) in the home garden. In 12 (29.3%) the place of bite was not documented. In 42% the bite took place between 4pm-8pm. The snake species was identified by carers in 19 (46%) and confirmed by a doctor in 16 (39%) by identifying the dead snake. Of the 16 snakes brought for identification., 8 were hump-nosed vipers, 2 were Russell vipers, one was a krait and the rest were non-venomous species. Definite puncture marks were seen in 17 (41.4%) and were on the lower limbs in 11 (26.8%) and on the upper limbs in 6 (14.6%). First aid was given to 12 (29%) of the victims and the median time taken to reach hospital was 30 minutes (range 10 minutes to 15 hours). Nephrotoxicity developed in 1 (2.4%) (Russell viper bite). Antivenom was required by only 4 children in whom Russell viper bite was either suspected or confirmed. Three children developed reactions to antivenom. There were no deaths. None required intensive care. The median stay in hospital was 1 day (range 1-5 days) with 35 (94.6%) children being discharged home within 2 days. CONCLUSIONS: Snakebite in children was mainly diagnosed on circumstantial evidence, and mostly occurred in and around their homes. The outcome was good in all patients probably because the hump-nosed viper or non-venomous snakes were the offenders in most cases in this study.Item Snakebites in children - a five year retrospective review of victims admitted to two hospitals in Sri Lanka(Sri Lanka Medical Association, 2012) Jayasinghe, Y.C.; Kasturiratne, A.; Somaraweera, S.A.S.G.; de Silva, H.J.INTRODUCTION: Snakebite in children causes great parental concern and medical unease. AIMS: To determine characteristics of paediatric snakebite in two hospitals, in the wet zone (Colombo North Teaching Hospital (CNTH) and dry zone (Base Hospital Polonnaruwa-BHP). METHODS: A retrospective study collected data on snakebite by reviewing records of children admitted to CNTH and BHP from January 2007 to December 2011. RESULTS: There were 188 snakebite victims (CNTH 71, BHP 117).Similarities in the two cohorts were (CNTH and BHP -M:F=35:36and 64:53; mean age 6 years (SD3) and 7 years (SD3); definite bites 30(53.6%) and 39(37.5%); circumstantial evidence in 57(80.3%) and 84(71.8%);time of bite: between 4- 8pm 42.6% and 47.2%. Majority of confirmed bites were HNV (60%) in CNTH and Kraits (30.8%) in BHP. Differences in the cohorts were :place of bite: in and around the home, median time from bite to hospital, administration of first aid, antivenom use, intensive care, median (range) duration of hospitalization and deaths (CNTH vs BHP): 37(56.9%) and 29(27.6%),35 vs 102.5 minutes, 21.4% vs 1%, 5.6% vs 17.1%, 1.4% vs 5.1%, 1 (1-7) days vs 2 (1-13), 0 vs 3.4% (Krait bites). CONCLUSIONS: Snakebites occur in ambulatory children, diagnosed mainly on circumstantial evidence and occur in and around homes irrespective of geographic location. Clinical features and outcome depend on offending species and availability of resources.