Shalya Shalakya

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    Herbo-electronic device for mosquito repellent and air sterilization
    (Young Ayurveda Researchers' & Innovators' Symposia -YARIS 2019, 2019) Weerasooriya, W.A.A.P.S.; Gunathilaka, T.K.N.C.; Rajapaksha, R.M.M.D.; Gunarathna, B.P.; Wasana, P.D.L.; Peiris, K.P.P.
    Mosquitoes are major problem that spread malaria and other diseases, such as dengue, chikungunya, and Yellow fever. There are two peak seasons for Dengue transmission in Sri Lanka: one is from October to December; another is from May to July. A mosquito repellent doesn't actually kill mosquitoes. Repellents work by making people less attractive to mosquitoes, so they're less likely to bite above chemicals may harm to the skin and respiratory system badly. But there are other options that are deemed "natural" because they are derived from natural materials such as plants.Impregnated with naturally repellent essential oils, the aromatic bands are designed to drive away mosquetos without saturating the skin with repellents. They smell strong, can be sniffed from up to 10 feet away,for more than 20-30 minutes and are nontoxic and adjustable to fit children through adults.They smell good and instill confidence in their active ingredients, but we still found ourselves the time which need exact mosquitoes and gnats repllent. As ingredients of this device we used mixture of citronella oil, cedar oil, lemon-grass oil and coconut oil geranium oil, clove oil,neem oil and known herbal repellents maduruthala,Agil,suduhadun,gugul, katphala, jatamansha, dummala that all derived from plants.the combination of herbo-electronic mosquito repellers, devices fit with repellent mats which release chemicals. The chemicals are heated by a fuel cartridge or circulated by a battery-powered fan. this one does not produce any foul smell, nor should the stuff be applied on the skin or clothes. Repellents have prevented countless cases of malaria, dengue. Transmission by arthropods fever, encephalitis, and other mosquito-borne diseases. Chemical substances that have repellent effects enable us to go places and do things in insect- and disease-infested areas while avoiding disease and it purified of air and that can be used as a air sterilizer in domestic environments and.
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    Valuable Assessment of Quality of Patoladi Lepa: An Ayurvedic Paste
    (Journal of Traditional Medicine and Clinical Naturopathy, open access journal, 2016) Kumaradharmasena, L.S.P.; Fernando, P.I.P.K.; Arawwawala, L.D.A.M.; Kamal, S.; Peiris, K.P.P.
    More than one fourth of world population is suffering from dental caries. It is a burden to governments of both developed and developing countries as they have to spend lot of money on treatments for dental caries. PatoladiLepa is an Ayurvedic paste used for dental caries and it consists of 7 plant ingredients, rock salt and honey. The objective of the current research was to determine the organoleptic properties, pH value, total ash, water soluble ash, acid insoluble ash and heavy metals such as Arsenic (As) and Lead (Pb) in PatoladiLepa using standard protocols. Moreover, Thin Layer Chromatography (TLC) fingerprint was developed for the paste using dichloromethane, cyclohexane and methanol in a ratio of v/v. According to the results, PatoladiLepa appeared to be semi solid, blackish brown with pungent taste. In addition, pH value, total ash, water soluble ash, acid insoluble ash were 5.8± 1 at 290C, 12.1 ± 0.0% w/w, 1.8 ± 0.0% w/w and 0.24 ± 0.0% w/w respectively. As and Pb were not present in PatoladiLepa. In conclusion, quality control parameters were established for PatoladiLepa for the first time.
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    The efficacy of herbal tea as preventive measure for allergic rhinitis
    (International Journal of Multidisciplinary Research and Development, 2019) Peiris, K.P.P.; Samaranayake, G.V.P.; Senadheera, M.P.R.S.
    Allergic rhinitis is an atopic disease. Atopic allergy is a type —I hypersensitivity reaction which produces IgE antibodies to allergens like pollen, dust, etc. In Ayurveda direct reference of allergic rhinitis is not available, but concept of allergy is scientifically explained under 'Asatmaja vyadhi' while its effects are explained in context of hereditary, Viruddhahara, Dushi visha and Ritu sandhi. Various types of Pratishyaya are explained clearly in all Samhita's. However, symptoms of Vataja pratishyaya like Tanu nasa srava (rhinorrhea), Shirah shoola (headache), Kshavathu (sneezing) more related with symptoms of allergic rhinitis. In the present study, patients of allergic rhinitis are evaluated on the basis of general evaluation scale consisting parameters like nasal obstruction, sneezing, itching nose etc. In the clinical study 30 patients were selected in age between 16-60 years irrespective of their sex, religion, occupation and habitat etc. They were treated with herbal tea for 14 days in their tea time 5g of tea bag. All of them were completed the treatment accurately and the follow up study continued up to two weeks after the treatment. According to analysis, it can be concluded that, the herbal tea has been shown reducing the symptoms of allergic rhinitis like nasal obstruction, sneezing, itching. While assessing the total effect of therapy, complete remission was observed in 16.7% (n=5), marked improvement was 33.3% (n=IO) and moderate improvement was 50% (n=15). During follow-up period recurrences were observed in the symptoms of running nose. Therefore it is most suitable as a preventive measure to control and cure the disease.
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    Standardization of Bakuladi Gandusha against the laboratory specimen of Staphylococcus aureus
    (European Journal of Biomedical and Pharmaceutical Sciences, 2020) Peiris, K.P.P.; Wickramasinghe, A. D.; Weerasooriya, W.A.A.P.S.
    The Ayurveda and Traditional medical systems are used mainly by using herbal and mineral preparations for the treatment of diseases. Ayurveda recommends Gandüsha (mouthwash) as a specialized local therapy for good oral hygiene which maintains and promotes the oral hygiene by exerting the cleansing action to increasing the defense mechanism in the oral cavity. Medicinal plants included in herbal formulas are contained many types of anti- microbial compounds which is naturally occurring and having minimum side effects. In this study Staphylococcus aureus was used to check anti-microbial properties in standardization of Gandusha. According to the observations, Bakuladi Gandusha mostly used in Out Patient Department of Shalakya at Gampaha Wickramarachchi Ayurveda Teaching Hospital, Sri Lanka and has been clinically proved with successful results in patients of periodontal diseases. The main purpose of this study is to identify maximum effective concentration of this Gandusha, which have the anti-bacterial effect against staphylococcus aureus by Anti Bacterial Susceptibility Test (ABST). According to Gandusha paribhasha, Bakuladi decoction was diluted in to series of concentrations. Four samples of decoction on the bacterial strain were evaluated by using well diffusion method to evaluate the highest Inhibitory Zone Diameter (IZD)with in the concentration series for antimicrobial activity. The samples of Bakuladi Gandusha has got the positive antibacterial effect p
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    Comparative study on different treatment modules in the management of Fistula – In - Ano (Bhagandara)
    (International Journal of Current Advanced Research, 2020) Samaranayake, G.V.P.; Pushpakumara, A.A.J.; Peiris, K.P.P.
    Bhagandara is a common disease occurring in the ano-rectal region. Acharya Susruta, the father of surgery has included this disease as one among the Ashtamahagada. It can be correlated with Fistula-in-ano as described in western medical science. Fistula-in-ano is a track lined by granulation tissue which opens deeply in the anal canal or rectum and superficially on the skin around the anus. The incidence of a Fistula-in-ano developing from an anal abscess ranges from 26-38%. The prevalence in men is 12.3 cases per 100 ,000 populations and in women are 5.6 cases per 100,000 populations. The male to female ratio is 1.8: l. The mean age of patients is 38.3 years. This randomized prospective cohort clinical study was done to compare and evaluate the effect of new herbal formulation consisting of Vitex nigundo(root), Crativa adansoni (bark), Ricinus communis (bark), Plumbago indica(root) in managing fistula-in-ano conditions of patients in comparison to the effect of tripala decoction and kshara sutra. The patients were selected according to the selection criteria and randomly assign in to 2 groups (Group A, Group B) consisting of 20 patients for each. The patients of Group A was be treated with, Tripala decoction, kshara sutra and prescribed dietary management. The patients of group B were treated with, new herbal formulation, kshara sutra and prescribed dietary management during the period of 8 weeks. In the group A and group B mean changes or decrement of pain, burning sensation, itching and discharge, P values = 0.00 95% confidence level P < 0.05 both groups are same P=O.()()O. Therefore, no difference between both groups and it shows statistically significant. In the group A mean decrement of length of the fistulous track P value p = 0.005 at confidence level P < 0.05. It shows a significant decrement of the length of fistulous track statistically in 95% confidence level. In the group B mean decrement of length of fistulous track P value p = 0.000 at 95% confidence level P < 0.05. It shows a significant decrement of the length of fistulous track statistically in 95% confidence level. But mean decrement of length of fistulous track of the group B greater than that of group A, which means group B more statistically significant. Finally, based on the observed results and the pharmacodynamic properties of both treatment protocols, it may be concluded that new herbal formulation + kshara sutra + dietary management treatment module is more effective than Tripala decoction + kshara sutra + dietary management in the management of fistula-in-ano.
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    Comparative anti -plaque effect of herbal dental formula
    (International Journal of Current Advanced Research, 2020) Peiris, K.P.P.; Rupasinghe, R.A.A.N.
    Ayurveda and Sri Lankan traditional medical system devotes a significant importance to oral health problems on its preventive aspect rather than curative. This herbal formulation is specified as a dentifrice in Thalpathe Piliyam. But it was not scientifically evaluated. Therefore, this study was carried out to evaluate the effectiveness of reducing plaque accumulation on teeth, maintenance of oral hygiene and compare the efficacy of powder with the novel toothpaste. Forty patients were selected with written consent from Dental OPD. They were randomly divided in to two groups; group A and B (20 patients in each) irrespective of their sex, religion, habitat etc. Group A was advised to brush twice a day for 01 month by using the toothpaste and Group B from same formula as in powder form. Oral Hygiene Index (OHI -S), Calculus Index (CI - S), Debris Index (DI —S) and Plaque Index (P Il) were used as objective criteria. According to the statistical analysis, it can be concluded that clinical effectiveness of toothpaste is more significant than tooth powder. Therefore, long term studies should be carried out to confirm the result.
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    Comparative anti -plaque effect of herbal dental formula
    (International Journal of Current Advanced Research, 2020) Peiris, K.P.P.; Rupasinghe, R.A.A.N.
    Ayurveda and Sri Lankan traditional medical system devotes a significant importance to oral health problems on its preventive aspect rather than curative. This herbal formulation is specified as a dentifrice in Thalpathe Piliyam. But it was not scientifically evaluated. Therefore, this study was carried out to evaluate the effectiveness of reducing plaque accumulation on teeth, maintenance of oral hygiene and compare the efficacy of powder with the novel toothpaste. Forty patients were selected with written consent from Dental OPD. They were randomly divided in to two groups; group A and B (20 patients in each) irrespective of their sex, religion, habitat etc. Group A was advised to brush twice a day for 01 month by using the toothpaste and Group B from same formula as in powder form. Oral Hygiene Index (OHI -S), Calculus Index (CI - S), Debris Index (DI —S) and Plaque Index (P Il) were used as objective criteria. According to the statistical analysis, it can be concluded that clinical effectiveness of toothpaste is more significant than tooth powder. Therefore, long term studies should be carried out to confirm the result.
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    Anti-inflammatory and Analgesic activities of Dashana Samskara Churna and its' paste form
    (Indian Journal of Natural Products and Resources, 2011) Peiris, K.P.P.; Ashok, B.K.; Manjusha, R.; Ravishankar, B.
    Anti-inflammatory and analgesic activities of Dashana Samskara Chuma and its paste form were examined in different animal models. Anti-inflammatory activity was evaluated in acute, sub-acute and chronic inflammatory models and compared with Phenylbutazone, Diclofenac sodium and Dexomethasone standards, respectively. Analgesic activity was evaluated in formalin induced paw licking (chemically induced pain) and tail flick method (thermally induced pain) where Indomethacin and Pentazocine were used as standard drugs, respectively. Test formulation in the form of paste inhibited the carrageenan induced paw oedema (P<0.05), formalin induced paw licking (P
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    Analgesic Activity of Water Extract of Spilanthes acmella Flowers on Rats
    (Journal of Trop medical plants, 2001) Peiris, K.P.P.; Silva, G.K.J.; Ratnasooriya, W.D.
    The objective of this study was to evaluate the analgesic potential of fresh flowers of Spilanthes acmella Murr. (family: Compositae) used by some Sri Lankan traditional medical practitioners to suppress toothache. Different doses of water extract of fresh flowers (111,335 and 671 mg kg-1 ) were orally administered to male rats and their analgesic potential was determined at different post treatment periods by using hot plate and tail flick tests. Sedative potential of the extract was evaluated by using rat hole board technique. The extract was well tolerated. A dose-dependent analgesic activity with a EC50 =313 mg kg-1was evident when evaluated in hot plate but not in tail flick test. This analgesic activity had a rapid onset and short duration of action and was not blocked by naloxone, an opioid receptor antagonist. The mid dose of the also induced significant sedation, It is concluded that the analgesic activity is mediated supra-spinally accompanied with sedation.
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    An Ayurvedic Appraoch in the management of Ashmari (Urolithiasis)
    (International Journal of Current Innovations in Advanced Research, 2019) Samaranayake, G.V.P.; Peiris, K.P.P.; Pushpakumara, A.A.J.
    In ancient centuries urolithiasis was often a disease, with a catastrophic outcome all too often leading to the patient's death. Even today, urolithiasis is the one of the most common affliction of the urinary tract. Detailed medical literature on urolithiasis is available from ancient India. As per classics, Ashmari is included in Ashtamahagada due to its fatal nature. Description of Ashmari is found in almost all Samhita Of Ayurveda as etiopathogenesis, classification, symptomatology, complications and management in a most scientific manner- Modem science also emphasizes on involvement of various factors like heredity, age, sex, metabolic disorders, hydration status, mineral content of water, nutritional deficiency, etc. For urinary stone formation. Urolithiasis typically occurs in middle age which is the most productive years of life. It causes pain, loss of working time, medical expenses, needs for hospitalization as well as it is infrequent cause of renal failure and death. Different management of urolithiasis has been developed in modern system but inspite of all these techniques, surgery remain treatment of choice. Even after surgery patients have to take medicines to check its further recurrence. In this way the need of medicinal treatment is always required.