A Comparative Study on the Anti-microbial efficacy of Two Ayurveda Powders (Prathisarana) Used in Periodontal Disease

Abstract

Kushtadi (KU) and Karanjadi (KR) are prominently used Ayurvedic powders (Prathisarana) in the management of periodontal diseases. This study was carried out for the determination of antimicrobial efficacy of these two drugs using standard Antimicrobial Sensitivity Test against Candida albicans and a fungal culture isolated from a patient. The Antimicrobial Sensitivity Test was performed according to the Well diffusion method having 6 mm diameter wells on Sabouraud Dextrose Agar (SDA). Each well was loaded with test drugs mixed in 20 gl of sterile distilled water and fluconazole 2.5 mg/ml as the positive control. According to the results, KR showed an average Inhibition Zone Diameter (iZD) of 20 mm for the isolated culture while KU did not show any inhibition. The results were similar for Candida albicans and KR showing IZD 18 mm, KU IZD 0 mm while positive control giving an Inhibition of 25 mm. Therefore, it can be concluded that Candida albicans and the isolated culture were sensitive Only for KR making it the only effective drug out of the two drugs tested in this study.