Browsing by Subject "Drug Resistance"

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Chloroquine resistant falciparum malaria among security forces personnel in the Northern Province of Sri Lanka

Hapuarachchi, H.A.C.; Dayanath, M.Y.D.; Abeysundara, S.; Bandara, K.B.A.T.; Abeyewickreme, W.; de Silva, N.R. (Sri Lanka Medical Association, 2004)

OBJECTIVE: To determine the occurrence and species distribution of malaria and the extent of chloroquine resistance among security forcespersonnel in a selected region of the Northern Province of Sri Lanka. DESIGN: A ...
Genetic composition of Plasmodium falciparum in relation to drug resistance and disease transmission in Sri Lanka

Hapuarachchi, H. C. (University of Kelaniya, 2006)

Malaria has been an important communicable disease in Sri Lanka. Even though P. vivax is the predominant species, there has been an increase in the proportion of chloroquine resistant P. falciparum infections in the country ...
Isothermal Diagnostic Assays for monitoring single nucleotide polymorphisms in Necator americanus associated with Benzimidazole drug resistance

Rashwan, N.; Bourguinat, C.; Keller, K.; Gunawardena, N.K.; de Silva, N.; Prichard, R. (Public Library of Science, 2016)

BACKGROUND: Soil-transmitted helminths (STHs) are the most prevalent intestinal helminths of humans, and a major cause of morbidity in tropical and subtropical countries. The benzimidazole (BZ) drugs albendazole (ABZ) and ...
Superoxide dismutase and pyruvate ferrodoxin oxidoreductase involvement in mechanisms of metronidazole resistance in Entamoeba histolytica

Samarawickrema, N.A.; Brown, D.M.; Upcroft, J.A.; Thammapalerd, N.; Uproft, P. (Oxford University Press, 1997)

Metronidazole resistance has been induced in an axenic strain of Entamoeba histolytica (HTH-56:MUTM) following continuous exposure to steadily increasing drug concentrations. The drug-resistant line is routinely maintained ...

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