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Browsing by Author "Lee, C.F."

Browsing by Author "Lee, C.F."

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  • Baseline characteristics and treatment response of patients from the Philippines in the CHIMES study 
    Navarro, J.C.; Gan, H.H.; Lao, A.Y.; Baroque, A.C.; Hiyadan, J.H.; Chua, C.L.; San Jose, M.C.; Advincula, J.M.; Lee, C.F.; Bousser, M.G.; Chen, C.L.; CHIMES Study Investigators (38); de Silva, H.A. CHIMES Study Investigator; Ranawaka, U. CHIMES Study Investigator; Wijekoon, N. CHIMES Study Investigator (Wiley-Blackwell, 2014)
    BACKGROUND: The CHIMES Study compared MLC601 with placebo in patients with ischemic stroke of intermediate severity in the preceding 72 h. Sites from the Philippines randomized 504 of 1099 (46%) patients in the study. We ...
  • Chinese medicine NeuroAiD efficacy on stroke recovery - extension study (CHIMES-E): A multicenter study of long-term efficacy 
    Venketasubramanian, N.; Young, S.H.; Tay, S.S.; Umapathi, T.; Lao, A.Y.; Gan, H.H.; Baroque II, A.C.; Navarro, J.C.; Chang, H.M.; Advincula, J.M.; Muengtaweepongsa, S.; Chan, B.P.; Chua, C.L.; Wijekoon, N.; de Silva, H.A.; Hiyadan, J.H.; Suwanwela, N.C.; Wong, K.S.; Poungvarin, N.; Eow, G.B.; Lee, C.F.; Chen, C.L. (Karger Publisher, 2015)
    BACKGROUND: The CHInese Medicine NeuroAiD Efficacy on Stroke recovery (CHIMES) study was an international randomized double-blind placebo-controlled trial of MLC601 (NeuroAiD) in subjects with cerebral infarction of ...
  • Chinese medicine neuroaid efficacy on stroke recovery: a double-blind, placebo-controlled, randomized study 
    Chen, C.L.; Young, S.H.; Gan, H.H.; Singh, R.; Lao, A.Y.; Baroque, A.C.; Chang, H.M.; Hiyadan, J.H.; Chua, C.L.; Advincula, J.M.; Muengtaweepongsa, S.; Chan, B.P.; de Silva, H.A.; Towanabut, S.; Suwanwela, N.C.; Poungvarin, N.; Chankrachang, S.; Wong, K.S.; Eow, G.B.; Navarro, J.C.; Venketasubramanian, N.; Lee, C.F.; Bousser, M.G.; CHIMES Study Investigators (Lippincott Williams and Wilkins, 2013)
    BACKGROUND AND PURPOSE: Previous clinical studies suggested benefit for post stroke recovery when MLC601 was administered between 2 weeks and 6 months of stroke onset. The Chinese Medicine Neuroaid Efficacy on Stroke ...
  • Effect of Combined Treatment with MLC601 (NeuroAiDTM) and Rehabilitation on Post-Stroke Recovery: The CHIMES and CHIMES-E Studies 
    Suwanwela, N.C.; Chen, C.L.H.; Lee, C.F.; Young, S.H.; Tay, S.S.; Umapathi, T.; Lao, A.Y.; Gan, H.H.; Baroque li, A.C.; Navarro, J.C.; Chang, H.M.; Advincula, J.M.; Muengtaweepongsa, S.; Chan, B.P.L.; Chua, C.L.; Wijekoon, N.; de Silva, H.A.; Hiyadan, J.H.B.; Wong, K.S.L.; Poungyarin, N.; Eow, G.B; Venketasubramanian, N.; CHIMES-E Study Investigators (Karger, 2018)
    BACKGROUND AND PURPOSE: MLC601 has been shown in preclinical studies to enhance neurorestorative mechanisms after stroke. The aim of this post hoc analysis was to assess whether combining MLC601 and rehabilitation has an ...
  • Effects of MLC601 on early vascular events in patients after stroke: the CHIMES study 
    Chen, C.L.; Venketasubramanian, N.; Lee, C.F.; Wong, K.S.; Bousser, M.G.; CHIMES Study Investigators; de Silva, A. with 38 CHIMES Study Investigators (Lippincott Williams and Wilkins, 2013)
    BACKGROUND AND PURPOSE: Early vascular events are an important cause of morbidity and mortality in the first 3 months after a stroke. We aimed to investigate the effects of MLC601 on the occurrence of early vascular events ...
  • Prognostic factors and pattern of long-term recovery with MLC601 (NeuroAiD™) in the chinese medicine neuroAiD efficacy on stroke recovery - extension study 
    Venketasubramanian, N.; Lee, C.F.; Young, S.H.; Tay, S.S.; Umapathi, T.; Lao, A.Y.; Gan, H.H.; Chua, C.L.; Wijekoon, N.; de Silva, H.A.; Hiyadan, J.H.; Suwanwela, N.C.; Wong, K.S.; Poungvarin, N.; Eow, G.B.; Chen, C.L.; CHIMES-E Study Investigators (Karger, 2017)
    BACKGROUND: The Chinese Medicine NeuroAiD Efficacy on Stroke recovery - Extension (CHIMES-E) study is among the few acute stroke trials with long-term outcome data. We aimed to evaluate the recovery pattern and the influence ...
  • Synergistic effect of combining MLC601 and rehabilitation on post-stroke recovery: The Chimes-E Study 
    Suwanwela, N.; Lee, C.F.; Christopher, L.H.; Chen; Sherry, H.; Young; Tay, S.S.; Umapathi, T.; Lao, A.Y.; Gan, H.H.; Alejandro, C.; Baroque; Jose, C.; Navarro; Hang, H.M.; Joel, M.; Advincula; Muengtaweepongsa, S.; Chan, B.P.L.; Chua, C.L.C.; Wijekoon, N.; de Silva, H.A.; Hiyadan, J.H.B.; Wong, K.S.L.; Poungvarin, N.; Eow, G.B.; Venketasubramanian, N. (Asia Pacific Stroke Organization, Hong Kong Stroke Society and Jiangsu Stroke Association & karger publishing, 2017)
    BACKGROUND AND RATIONALE: MLC601 has been shown to enhance natural neuro-repair mechanisms after stroke and may also facilitate rehabilitation-stimulated recovery processes. We aimed to assess the effect of MLC601 and ...

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