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DC Field | Value | Language |
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dc.contributor.author | Peiris, D. | - |
dc.contributor.author | Pathmeswaran, A. | - |
dc.contributor.author | Jayasinghe, U.N. | - |
dc.date.accessioned | 2015-10-05T04:08:37Z | - |
dc.date.available | 2015-10-05T04:08:37Z | - |
dc.date.issued | 2005 | - |
dc.identifier.citation | The Ceylon Medical Journal. 2005; 50(Supplement 1):14 | en_US |
dc.identifier.issn | 0009-0875 (Print) | - |
dc.identifier.uri | http://repository.kln.ac.lk/handle/123456789/9912 | - |
dc.description | Oral Presentation Abstract (OP18), 118th Annual Scientific Sessions, Sri Lanka Medical Association, 2005 Colombo, Sri Lanka | en_US |
dc.description.abstract | OBJECTIVES: To assess the success of treatment of ALL within the constraints of a specialized unit in Sri Lanka METHODS: We analysed 51 consecutive cases of ALL presenting to a single unit within a 65 month period from 01-6-1999. (Prospective data from June 2002). Difficulties and constraints that we encountered are described. Diagnosis was made by bone marrow morphology. Treatment was with UKALL X Protocol until March 2002. Thereafter a modified MRC 99 protocol was adopted. Results: 51 children were treated and followed up for 1 month to 56 months, (average of 20 months each). There were 31 males (60%). The median age was 4.2 years. 43 children were within 2-10 year age group. Eight children had initial white cell count of more than 50 x 109/mm3. Remission was induced in 47 (92%) with induction therapy. There were no induction cTeaths. Four children (8%) were resistant to induction. Eleven children (24%) relapsed during the follow up period. Of the relapses, 9 are living with a median survival of 17 months. There were 8 deaths. There are 43 survivors at the end of study period. Based on survival analysis done by the Kaplan- Meier method, it was estimated 89, 85, and 78% of patients could survive for 1. 2 and 3 years respectively. CONCLUSIONS: We conclude that Childhood ALL could be treated safely within the setting described and early results are encouraging. (In leading centers in the developed world, probability of relapse free 5 year survival is around 80% + 8) | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | Sri Lanka Medical Association | en_US |
dc.subject | lymphoblastic leukemia | en_US |
dc.title | Early experience in treatment of childhood acute lymphoblastic leukemia (ALL) | en_US |
dc.type | Article | en_US |
Appears in Collections: | Conference Papers |
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