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DC Field | Value | Language |
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dc.contributor.author | Manamperi, N.H. | en_US |
dc.contributor.author | Athapaththu, A.M.M.H. | en_US |
dc.contributor.author | Premawansa, G. | en_US |
dc.contributor.author | Wellawaththage, C. | en_US |
dc.contributor.author | Jayarathna, T. D. S. S. | en_US |
dc.contributor.author | Abeyewickreme, W. | en_US |
dc.contributor.author | Hapugoda, M.D. | en_US |
dc.date.accessioned | 2015-08-29T21:33:47Z | en_US |
dc.date.available | 2015-08-29T21:33:47Z | en_US |
dc.date.issued | 2010 | en_US |
dc.identifier.citation | Tropical Diseases Future Threats and New Paradigms, Proceedings of the Joint International Tropical Medicine Meeting & International Malaria Colloquium 2010 :239 | en_US |
dc.identifier.uri | http://repository.kln.ac.lk/handle/123456789/9359 | en_US |
dc.description | Poster Presentation Abstract (No. 70) of Joint International Tropical Medicine Meeting (JITMM 2010) & International Malaria Colloquium (IMC2010) 1-3 December 2010 Bangkok, Thailand | en_US |
dc.description.abstract | OBJECTIVES: Sri Lanka has experienced explosive outbreaks of dengue infection in 2009 and 2010. It has been identified that DEN- 3 and DEN- 2 were the predominant serotypes with DEN-1 and DEN- 4 circulating at a lower level in previous dengue outbreaks during 2003-2006, Objective of this study was to identify the circulating serotype/s during 2009 - 2010 outbreaks. METHODOLOGY: A prospective study was carried out at North Colombo Teaching Hospital, Sri Lanka during December 2009-August 2010. Clinically suspected dengue patients, with fever less than 5 days were recruited. An interviewer administered questionnaire was filled for each patient, by a Medical Officer. Venous blood samples confirmed for the presence of dengue virus by RT-PCR were typed by Semi-Nested PCR. RESULTS: Out of the 209 patients recruited in the study 80 (38%) were positive for dengue virus by RT-PCR. Of the positives, 43 (54%) were typed and circulation of all 4 serotypes was observed- Of the 43 positives, presence of DEN-1, DEN-2, DEN-3 and DEN-4 serotypes was 34 (79%), 3 (7%), 2 (5%) and 3 (7%) respectively DEN-1 was the predominant serotype in the recent epidemics which was circulating at a low level in previous epidemics. In DEN-1 infected patients, the mean platelet value was 58,588/ rnm3 and the mean PCV value was 41.4%. Associated symptoms such as headache, retro-orbital pain, neck pain and limb pain were present in 94% (32/34), 59% (20/34), 24% (8/34J and 91% (31/34) patients respectively. Bleeding manifestation developed in 47 % (16/34) patients. The mortality rate ranged from 0.7%- 1.0% during the recent outbreaks. Acknowledgement: Financial and technical assistance from the International Centre for Genetic Engineering and Biotechnology (ICGEB CRP/ SRI08-02) and the International Atomic Energy Agency (IAEA SRI 5/042) is gratefully acknowledged. | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | Faculty of Tropical Medicine, Mahidol University | en_US |
dc.subject | Dengue | en_US |
dc.subject | Dengue-epidemiology | en_US |
dc.title | Shifting of circulating serotypes in dengue outbreaks during 2009/2010 in Sri lanka | en_US |
dc.type | Conference Abstract | en_US |
dc.identifier.department | Parasitology | en_US |
dc.identifier.department | Molecular Medicine Unit | en_US |
dc.creator.corporateauthor | Parasitology and Tropical Medicine Association of Thailand | en_US |
dc.creator.corporateauthor | SEAMEO Regional Tropical Medicine and Public Health Network | en_US |
dc.creator.corporateauthor | TROPMED Alumni Association | en_US |
Appears in Collections: | Conference Papers |
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