Please use this identifier to cite or link to this item:
http://repository.kln.ac.lk/handle/123456789/26788
Title: | First co-infection of malaria and hepatitis E diagnosed in Sri Lanka |
Authors: | Senarathne, S. Rajapakse, S. de Silva, H.J. Seneviratne, S. Chulasiri, P. Fernando, D. |
Keywords: | malaria hepatitis E co-infections |
Issue Date: | 2023 |
Publisher: | Sri Lanka Medical Association |
Citation: | Sri Lanka Medical Association, 136th Anniversary International Medical Congress. 2023; 68 (Supplement S):S101 |
Abstract: | INTRODUCTION: Imported malaria cases continue to be reported in Sri Lanka. Similarly, hepatitis E is also considered a travel associated imported disease in Sri Lanka. This is a report of the first co-infection of malaria and hepatitis E in Sri Lanka. OBJECTIVES: A 21-year-old European who visited Sri Lanka after a 2 months stay in India, was admitted to hospital with fever, vomiting, abdominal pain, and dark-coloured urine on the 4th day after his arrival. On examination, he had splenomegaly but no hepatomegaly. He had thrombocytopaenia; 89% neutrophils; 9% lymphocytes; elevated liver enzymes and hyperbilirubinaemia. Urine was positive for bile pigment. METHODS: Considering his travel history to India, he was tested for malaria. The rapid diagnostic test became positive for Plasmodium falciparum while microscopy showed P. falciparum ring stages with a parasite density of 120/μl. He was treated as for uncomplicated P. falciparum malaria with oral Artemisinin-based Combination Therapy. The patient became fever-free and blood smears became negative after 13 hours following 2 doses of antimalarials. RESULTS: However, his liver functions were further deranged with apparent jaundice (ALT: 250 U/L; AST: 175 U/L; ALP: 130 U/L; GGT: 179 U/L; total bilirubin: 10.65 mg/dL; direct bilirubin: 8.08 mg/dL; indirect bilirubin: 2.57 mg/dL). Further blood tests detected hepatitis E-specific IgM antibodies. He was treated with oral ursodiol but no specific antiviral was given. Following the completion of antimalarials, he was discharged from the hospital upon clinical recovery. CONCLUSION: Clinicians should be vigilant on travel-associated co-infections in patients who are diagnosed with imported malaria. |
Description: | Poster Presentation Abstract (PP 049), 136th Anniversary International Medical Congress, Sri Lanka Medical Association, 25th-28th July 2023, Colombo, Sri Lanka |
URI: | http://repository.kln.ac.lk/handle/123456789/26788 |
ISSN: | 0009-0875 |
Appears in Collections: | Conference Papers |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
Abstract-book-2023-FINAL-VERSION-2.0-101.pdf | 519.17 kB | Adobe PDF | View/Open |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.