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Title: | Is splenic stiffness measurement(SSM) better than Baveno VII criteria to predict oesophageal and cardio- fundal varices in patients with compensated advanced liver cell disease (cACLD)? |
Authors: | de Silva, A.P. Niriella, M.A. Nishad, A.A.N. Samarawickrama, V.T. Jayasundara, H. Ranawaka, C.K. de Silva, S.T. Withanage, M. Ediriweera, D. de Silva, H.J. |
Keywords: | Cirrhosis Varices Liver stiffness Splenic stiffness |
Issue Date: | 2023 |
Publisher: | Sri Lanka Medical Association |
Citation: | Sri Lanka Medical Association, 136th Anniversary International Medical Congress. 2023; 68 (Supplement S):S15 |
Abstract: | INTRODUCTION: Liver and splenic stiffness measurements (LSM and SSM) using transient elastography (TE) are being increasingly used as a screening tool to predict varices. OBJECTIVES: We aimed to test the utility of Baveno-VII criteria (LSM>25kPa, LSM>20kPa with platelet count <130,000 and LSM>15kPa with platelet count <110,000) and SSM to predict oesophageal and cardio-fundal varices in a cohort of Sri Lankan patients with aALCD. METHODS: Consecutive patients with newly diagnosed Child’s class A cALCD (non-viral, BMI<30) were recruited prospectively. They underwent upper gastrointestinal endoscopy by an endoscopist followed by a Fibroscan by an operator who is unaware of endoscopy findings using ECHOSENS-Fibroscan-502 to measure LSM and SSM. Validity measurements of three Baveno-VII criteria and SSM values to predict oesophageal and cardio-fundal varices were calculated. RESULTS: One hundred and seventy-four individuals were recruited [Mean (95%CI) age 61.4 (59.7-62.8) years, 110 males], and 106 had varices. Our results indicate that the three Baveno VII criteria had sensitivities of 61%, 63% and 42%, and specificities of 79%, 77% and 87%. SSM>30kPa alone or in combination with LSM>15kPa had sensitivity of 81&75%, specificity of 72&83%, PPV of 82&87%, NPV of 71&67% and accuracy of 78&78% consecutively to predict oesophageal and cardio-fundal varices. CONCLUSION: Baveno VII criteria had low sensitivity but high specificity to predict oesophageal and cardio-fundal varices. SSM>30kPa alone or in combination with LSM>15kPa seemed to predict oesophageal and cardio-fundal varices better. |
Description: | Oral Presentation Abstract (OP 012), 136th Anniversary International Medical Congress, Sri Lanka Medical Association, 25th-28th July 2023, Colombo, Sri Lanka |
URI: | http://repository.kln.ac.lk/handle/123456789/26768 |
ISSN: | 0009-0875 |
Appears in Collections: | Conference Papers |
Files in This Item:
File | Description | Size | Format | |
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Abstract-book-2023-FINAL-VERSION-2.0-15.pdf | 519.34 kB | Adobe PDF | View/Open |
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