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DC Field | Value | Language |
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dc.contributor.author | Atukorala, I. | |
dc.contributor.author | Downie, A. | |
dc.contributor.author | Pathmeswaran, A. | |
dc.contributor.author | Deveza, L.M.A. | |
dc.contributor.author | Chang, T. | |
dc.contributor.author | Zhang, Y. | |
dc.contributor.author | Hunter, D.J. | |
dc.date.accessioned | 2022-02-10T04:06:28Z | |
dc.date.available | 2022-02-10T04:06:28Z | |
dc.date.issued | 2022 | |
dc.identifier.citation | International Journal of Rheumatic Diseases.2022; 5(3):281-294.[Epub 2022 Jan 25] | en_US |
dc.identifier.issn | 1756-1841 | |
dc.identifier.uri | http://repository.kln.ac.lk/handle/123456789/24411 | |
dc.description | Indexed in MEDLINE. | en_US |
dc.description.abstract | Aim: It is unknown if pain in knee osteoarthritis (KOA) follows distinct patterns over the short term. Therefore, the aim of this study was to identify whether persons with a previous history of KOA pain fluctuations have distinct trajectories of pain over 90 days and to examine associations between baseline characteristics and pain trajectories. Method: People with a previous history of KOA were selected from a web-based longitudinal study. Baseline variables were sex, age, being obese/overweight, years of KOA, knee injury, knee buckling, satisfactory Lubben Social Support Score, pain and stress scales, Intermittent Constant Osteoarthritis Pain Score (ICOAP), medication use, and physical activity. Participants completed a Knee Injury and Osteoarthritis Outcomes Score (KOOS) pain subscale (KOOS-p, rated 0 = extreme to 100 = no knee problems) at 10-day intervals for 90 days. Short-term KOOS-p trajectories were identified using latent growth mixture modeling and the baseline risk factors for these pain trajectories were examined. Results: Participants (n = 313) had a mean age of 62.2 (SD ± 8.1) years and and a body mass index of 29.8 (SD ± 6.6) kg/m2 . The three-class latent growth mixture modeling quadratic model with best fit indices was chosen (based on lowest sample-size-adjusted Bayesian Information Criterion, high probability of belonging, interpretability). Three distinct pain trajectory clusters (over 90 days) were identified: low-moderate pain at baseline with large improvement (n = 11), minimal change in pain over 90 days (n = 248), and moderate-high pain with worsening (n = 46). Higher ICOAP (intermittent scale), perceived stress, negative affect score, and knee buckling at baseline were associated with a worse knee pain trajectory (P < 0.05). Conclusions: Persons with KOA showed unique short-term pain trajectories over 90 days, with distinct characteristics at baseline associated with each trajectory. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Wiley on behalf of the Asia Pacific League of Associations for Rheumatology | en_US |
dc.subject | Osteoarthritis | en_US |
dc.subject | Osteoarthritis, Knee | en_US |
dc.title | Short-term pain trajectories in patients with knee osteoarthritis | en_US |
dc.type | Article | en_US |
Appears in Collections: | Journal/Magazine Articles |
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